Optical coherence tomography and polarimetry of superficial skin biopsies
The goal. Of this study was to develop and assess the efficacy of polarization probing of biotissues in vitro. The method is based on the determination of polarization parameters of scattered radiation. Materials and methods. The well-known superficial epidermis stripping method was applied using th...
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| Format: | Article |
| Language: | English |
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State Scientific Center of Dermatovenereology and Cosmetology
2017-08-01
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| Series: | Vestnik Dermatologii i Venerologii |
| Subjects: | |
| Online Access: | https://www.vestnikdv.ru/jour/article/view/109 |
| _version_ | 1797721834030891008 |
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| author | S. R. Utz D. A. Zimnyakov E. M. Galkina E. M. Reshetnikova |
| author_facet | S. R. Utz D. A. Zimnyakov E. M. Galkina E. M. Reshetnikova |
| author_sort | S. R. Utz |
| collection | DOAJ |
| description | The goal. Of this study was to develop and assess the efficacy of polarization probing of biotissues in vitro. The method is based on the determination of polarization parameters of scattered radiation. Materials and methods. The well-known superficial epidermis stripping method was applied using the Sulfacrylate self-sterile medical adhesive. Small portions of thin layers of the adhesive were applied to slide plates and then to different skin sites. The corneous layer in the normal condition and in case of skin diseases (psoriasis, lichen acuminatus, discoid lupus erythematosus, alopecia, itching and demodectic mange) was examined based on the optical coherence tomography (OCT) method using the 0CS1300SS device (Thorlabs Inc, USA). Results. The authors obtained pictures visualizing the structural organization of different layers of the epidermis using the superficial epidermis biopsy method in case of lichen acuminatus, hyperkeratosis, itching and other skin diseases. Conclusion. This method ensures non-invasive high-precision measurement of the structure of different layers of the epidermis, which may be useful both for research purposes and practical dermatology. |
| first_indexed | 2024-03-12T09:39:56Z |
| format | Article |
| id | doaj.art-3a1461733e6344afb26dd6cf131f16fc |
| institution | Directory Open Access Journal |
| issn | 0042-4609 2313-6294 |
| language | English |
| last_indexed | 2024-03-12T09:39:56Z |
| publishDate | 2017-08-01 |
| publisher | State Scientific Center of Dermatovenereology and Cosmetology |
| record_format | Article |
| series | Vestnik Dermatologii i Venerologii |
| spelling | doaj.art-3a1461733e6344afb26dd6cf131f16fc2023-09-02T13:20:28ZengState Scientific Center of Dermatovenereology and CosmetologyVestnik Dermatologii i Venerologii0042-46092313-62942017-08-0101859110.25208/0042-4609-2015-0-1-85-91108Optical coherence tomography and polarimetry of superficial skin biopsiesS. R. Utz0D. A. Zimnyakov1E. M. Galkina2E. M. Reshetnikova3Saratov State Medical University named after V.I. RazumovskyYuri Gagarin State Technical University of SaratovSaratov State Medical University named after V.I. RazumovskySaratov State Medical University named after V.I. RazumovskyThe goal. Of this study was to develop and assess the efficacy of polarization probing of biotissues in vitro. The method is based on the determination of polarization parameters of scattered radiation. Materials and methods. The well-known superficial epidermis stripping method was applied using the Sulfacrylate self-sterile medical adhesive. Small portions of thin layers of the adhesive were applied to slide plates and then to different skin sites. The corneous layer in the normal condition and in case of skin diseases (psoriasis, lichen acuminatus, discoid lupus erythematosus, alopecia, itching and demodectic mange) was examined based on the optical coherence tomography (OCT) method using the 0CS1300SS device (Thorlabs Inc, USA). Results. The authors obtained pictures visualizing the structural organization of different layers of the epidermis using the superficial epidermis biopsy method in case of lichen acuminatus, hyperkeratosis, itching and other skin diseases. Conclusion. This method ensures non-invasive high-precision measurement of the structure of different layers of the epidermis, which may be useful both for research purposes and practical dermatology.https://www.vestnikdv.ru/jour/article/view/109поверхностная биопсия кожиоптическая когерентная томографияполяризацияструктура эпидермисадерматозыsuperficial skin biopsyoptical coherence tomographypolarizationstructure of epidermisdermatoses |
| spellingShingle | S. R. Utz D. A. Zimnyakov E. M. Galkina E. M. Reshetnikova Optical coherence tomography and polarimetry of superficial skin biopsies Vestnik Dermatologii i Venerologii поверхностная биопсия кожи оптическая когерентная томография поляризация структура эпидермиса дерматозы superficial skin biopsy optical coherence tomography polarization structure of epidermis dermatoses |
| title | Optical coherence tomography and polarimetry of superficial skin biopsies |
| title_full | Optical coherence tomography and polarimetry of superficial skin biopsies |
| title_fullStr | Optical coherence tomography and polarimetry of superficial skin biopsies |
| title_full_unstemmed | Optical coherence tomography and polarimetry of superficial skin biopsies |
| title_short | Optical coherence tomography and polarimetry of superficial skin biopsies |
| title_sort | optical coherence tomography and polarimetry of superficial skin biopsies |
| topic | поверхностная биопсия кожи оптическая когерентная томография поляризация структура эпидермиса дерматозы superficial skin biopsy optical coherence tomography polarization structure of epidermis dermatoses |
| url | https://www.vestnikdv.ru/jour/article/view/109 |
| work_keys_str_mv | AT srutz opticalcoherencetomographyandpolarimetryofsuperficialskinbiopsies AT dazimnyakov opticalcoherencetomographyandpolarimetryofsuperficialskinbiopsies AT emgalkina opticalcoherencetomographyandpolarimetryofsuperficialskinbiopsies AT emreshetnikova opticalcoherencetomographyandpolarimetryofsuperficialskinbiopsies |