Genetic Background Influences Adaptation To Cardiac Hypertrophy and Ca2+ Handling Gene Expression

Genetic Background Influences Adaptation To Cardiac Hypertrophy and Ca2+ Handling Gene Expression

Genetic variability has a profound effect on the development of cardiac hypertrophy in response to stress. Consequently, using a variety of inbred mouse strains with known genetic profiles may be powerful models for studying the response to cardiovascular stress. To explore this approach we looked a...

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Bibliographic Details
Main Authors: Steve B Waters, Doug eDiak, Matthew eZuckerman, Lara eLeoni, Paul Harvey Goldspink, Brian B Roman
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-03-01
Series:Frontiers in Physiology
Subjects:
Gene Expression
Heart
Hemodynamics
Hypertrophy
Mouse
Ca2+-handling
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphys.2013.00011/full

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