Application of comprehensive unit-based safety program model to improve chemotherapy-induced nausea and vomiting in patients with ovarian cancer: a retrospective study
Abstract Background To explore the effect of intervention programs constructed under the guidance of the comprehensive unit-based safety program (CUSP) model on chemotherapy-induced nausea and vomiting (CINV) in patients with ovarian cancer. Method According to the time of admission, 90 ovarian canc...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2023-07-01
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| Series: | Journal of Ovarian Research |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s13048-023-01230-1 |
| _version_ | 1797774011157970944 |
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| author | Aihua Liu Min Li Zhuo Liu Xinxin Xie Wen Yao Jingmin Wang Tingting Zhao Jie Yang |
| author_facet | Aihua Liu Min Li Zhuo Liu Xinxin Xie Wen Yao Jingmin Wang Tingting Zhao Jie Yang |
| author_sort | Aihua Liu |
| collection | DOAJ |
| description | Abstract Background To explore the effect of intervention programs constructed under the guidance of the comprehensive unit-based safety program (CUSP) model on chemotherapy-induced nausea and vomiting (CINV) in patients with ovarian cancer. Method According to the time of admission, 90 ovarian cancer chemotherapy patients in the first affiliated Hospital of Anhui Medical University from June 2019 to September 2020 were divided into an intervention group and a control group with 45 cases each. Both groups of patients received routine intervention, and the intervention group implemented the CUSP program on this basis. The intervention lasted 8 months. Before and after the intervention, the patients in the ward were used the Multinational Association of Supportive Care in Cancer (MASCC) Antiemesis Tool, the Functional Living Index-Emesis (FLIE), and the Hospital Anxiety and Depression Scale (HADS) for the effect evaluation. Results After the intervention, the degree of nausea and vomiting frequency in the intervention group were significantly lower than that in the control group, especially the degree of nausea in the delayed phase (P < 0.05). The score of the functional living index-emesis in the intervention group was significantly higher than that in the control group (P < 0.05), and the anxiety and depression in the intervention group were significantly relieved compared to the control group (P < 0.05). Conclusion The intervention program guided by the CUSP model can significantly alleviate patients’ nausea and vomiting, improve the quality of life, and relieve anxiety and depression. The CUSP model is suitable for clinical practice and has guiding significance for clinical work. |
| first_indexed | 2024-03-12T22:14:44Z |
| format | Article |
| id | doaj.art-3a1d129768d341d98396666034d9e55c |
| institution | Directory Open Access Journal |
| issn | 1757-2215 |
| language | English |
| last_indexed | 2024-03-12T22:14:44Z |
| publishDate | 2023-07-01 |
| publisher | BMC |
| record_format | Article |
| series | Journal of Ovarian Research |
| spelling | doaj.art-3a1d129768d341d98396666034d9e55c2023-07-23T11:22:30ZengBMCJournal of Ovarian Research1757-22152023-07-011611910.1186/s13048-023-01230-1Application of comprehensive unit-based safety program model to improve chemotherapy-induced nausea and vomiting in patients with ovarian cancer: a retrospective studyAihua Liu0Min Li1Zhuo Liu2Xinxin Xie3Wen Yao4Jingmin Wang5Tingting Zhao6Jie Yang7Department of Gynaecology, The First Affiliated Hospital of Anhui Medical UniversityDepartment of Gynaecology, The First Affiliated Hospital of Anhui Medical UniversityDepartment of Gynaecology, The First Affiliated Hospital of Anhui Medical UniversityDepartment of nursing management, The First Affiliated Hospital of Anhui Medical UniversityDepartment of Gynaecology, The First Affiliated Hospital of Anhui Medical UniversityDepartment of Gynaecology, The First Affiliated Hospital of Anhui Medical UniversityDepartment of Gynaecology, The First Affiliated Hospital of Anhui Medical UniversityDepartment of Gynaecology, The First Affiliated Hospital of Anhui Medical UniversityAbstract Background To explore the effect of intervention programs constructed under the guidance of the comprehensive unit-based safety program (CUSP) model on chemotherapy-induced nausea and vomiting (CINV) in patients with ovarian cancer. Method According to the time of admission, 90 ovarian cancer chemotherapy patients in the first affiliated Hospital of Anhui Medical University from June 2019 to September 2020 were divided into an intervention group and a control group with 45 cases each. Both groups of patients received routine intervention, and the intervention group implemented the CUSP program on this basis. The intervention lasted 8 months. Before and after the intervention, the patients in the ward were used the Multinational Association of Supportive Care in Cancer (MASCC) Antiemesis Tool, the Functional Living Index-Emesis (FLIE), and the Hospital Anxiety and Depression Scale (HADS) for the effect evaluation. Results After the intervention, the degree of nausea and vomiting frequency in the intervention group were significantly lower than that in the control group, especially the degree of nausea in the delayed phase (P < 0.05). The score of the functional living index-emesis in the intervention group was significantly higher than that in the control group (P < 0.05), and the anxiety and depression in the intervention group were significantly relieved compared to the control group (P < 0.05). Conclusion The intervention program guided by the CUSP model can significantly alleviate patients’ nausea and vomiting, improve the quality of life, and relieve anxiety and depression. The CUSP model is suitable for clinical practice and has guiding significance for clinical work.https://doi.org/10.1186/s13048-023-01230-1Comprehensive unit-based safety programChemotherapy-induced nausea and vomitingOvarian cancerQuality of lifeAnxietyDepression |
| spellingShingle | Aihua Liu Min Li Zhuo Liu Xinxin Xie Wen Yao Jingmin Wang Tingting Zhao Jie Yang Application of comprehensive unit-based safety program model to improve chemotherapy-induced nausea and vomiting in patients with ovarian cancer: a retrospective study Journal of Ovarian Research Comprehensive unit-based safety program Chemotherapy-induced nausea and vomiting Ovarian cancer Quality of life Anxiety Depression |
| title | Application of comprehensive unit-based safety program model to improve chemotherapy-induced nausea and vomiting in patients with ovarian cancer: a retrospective study |
| title_full | Application of comprehensive unit-based safety program model to improve chemotherapy-induced nausea and vomiting in patients with ovarian cancer: a retrospective study |
| title_fullStr | Application of comprehensive unit-based safety program model to improve chemotherapy-induced nausea and vomiting in patients with ovarian cancer: a retrospective study |
| title_full_unstemmed | Application of comprehensive unit-based safety program model to improve chemotherapy-induced nausea and vomiting in patients with ovarian cancer: a retrospective study |
| title_short | Application of comprehensive unit-based safety program model to improve chemotherapy-induced nausea and vomiting in patients with ovarian cancer: a retrospective study |
| title_sort | application of comprehensive unit based safety program model to improve chemotherapy induced nausea and vomiting in patients with ovarian cancer a retrospective study |
| topic | Comprehensive unit-based safety program Chemotherapy-induced nausea and vomiting Ovarian cancer Quality of life Anxiety Depression |
| url | https://doi.org/10.1186/s13048-023-01230-1 |
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