Extraneural metastatic gliosarcoma: A case report and review of the literature

Extraneural metastasis of gliosarcoma (GS) is a rare event. In this report, we describe a 15-year-old girl with a frontal GS who underwent complete resection, but developed tumor recurrence requiring a second operation after 3 years. Eight months after the second operation, she presented with a left...

Full description

Bibliographic Details
Main Authors: Thara Tunthanathip, Niti Tawaranurak, Kanet Kanjanapradit
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2020-01-01
Series:Glioma
Subjects:
Online Access:http://www.jglioma.com/article.asp?issn=2589-6113;year=2020;volume=3;issue=2;spage=76;epage=81;aulast=Tunthanathip
_version_ 1819058377850880000
author Thara Tunthanathip
Niti Tawaranurak
Kanet Kanjanapradit
author_facet Thara Tunthanathip
Niti Tawaranurak
Kanet Kanjanapradit
author_sort Thara Tunthanathip
collection DOAJ
description Extraneural metastasis of gliosarcoma (GS) is a rare event. In this report, we describe a 15-year-old girl with a frontal GS who underwent complete resection, but developed tumor recurrence requiring a second operation after 3 years. Eight months after the second operation, she presented with a left postauricular mass. The clinical, neuroimaging, and histopathological findings were described. We also conducted a literature review and identified 26 cases of GS with extraneural metastasis, including the current report. The prognosis of GS with extracranial metastasis was poor, with a median survival of approximately 8.0 months. The common metastatic organs were the lungs (65.4%), liver (34.6%), and skeleton (23.1%). We also discuss the pathogenesis of GS with extraneural metastasis. We report an unusual case of a pediatric patient with GS with extraneural metastasis, with a long survival. GS with extraneural metastasis should be considered as a differential diagnosis in patients with soft-tissue masses. This work was approved by the Ethics Committee of the Faculty of Medicine, Prince of Songkla University, Thailand (REC 62-259-10-1) on September 9, 2019.
first_indexed 2024-12-21T13:54:14Z
format Article
id doaj.art-3a20712e2f0e4eab8ccdeacaa2bae7cb
institution Directory Open Access Journal
issn 2589-6113
2589-6121
language English
last_indexed 2024-12-21T13:54:14Z
publishDate 2020-01-01
publisher Wolters Kluwer Medknow Publications
record_format Article
series Glioma
spelling doaj.art-3a20712e2f0e4eab8ccdeacaa2bae7cb2022-12-21T19:01:36ZengWolters Kluwer Medknow PublicationsGlioma2589-61132589-61212020-01-0132768110.4103/glioma.glioma_7_20Extraneural metastatic gliosarcoma: A case report and review of the literatureThara TunthanathipNiti TawaranurakKanet KanjanapraditExtraneural metastasis of gliosarcoma (GS) is a rare event. In this report, we describe a 15-year-old girl with a frontal GS who underwent complete resection, but developed tumor recurrence requiring a second operation after 3 years. Eight months after the second operation, she presented with a left postauricular mass. The clinical, neuroimaging, and histopathological findings were described. We also conducted a literature review and identified 26 cases of GS with extraneural metastasis, including the current report. The prognosis of GS with extracranial metastasis was poor, with a median survival of approximately 8.0 months. The common metastatic organs were the lungs (65.4%), liver (34.6%), and skeleton (23.1%). We also discuss the pathogenesis of GS with extraneural metastasis. We report an unusual case of a pediatric patient with GS with extraneural metastasis, with a long survival. GS with extraneural metastasis should be considered as a differential diagnosis in patients with soft-tissue masses. This work was approved by the Ethics Committee of the Faculty of Medicine, Prince of Songkla University, Thailand (REC 62-259-10-1) on September 9, 2019.http://www.jglioma.com/article.asp?issn=2589-6113;year=2020;volume=3;issue=2;spage=76;epage=81;aulast=Tunthanathipextracranial metastasisextraneural metastasisgliosarcomahigh-grade gliomamalignant glioma
spellingShingle Thara Tunthanathip
Niti Tawaranurak
Kanet Kanjanapradit
Extraneural metastatic gliosarcoma: A case report and review of the literature
Glioma
extracranial metastasis
extraneural metastasis
gliosarcoma
high-grade glioma
malignant glioma
title Extraneural metastatic gliosarcoma: A case report and review of the literature
title_full Extraneural metastatic gliosarcoma: A case report and review of the literature
title_fullStr Extraneural metastatic gliosarcoma: A case report and review of the literature
title_full_unstemmed Extraneural metastatic gliosarcoma: A case report and review of the literature
title_short Extraneural metastatic gliosarcoma: A case report and review of the literature
title_sort extraneural metastatic gliosarcoma a case report and review of the literature
topic extracranial metastasis
extraneural metastasis
gliosarcoma
high-grade glioma
malignant glioma
url http://www.jglioma.com/article.asp?issn=2589-6113;year=2020;volume=3;issue=2;spage=76;epage=81;aulast=Tunthanathip
work_keys_str_mv AT tharatunthanathip extraneuralmetastaticgliosarcomaacasereportandreviewoftheliterature
AT nititawaranurak extraneuralmetastaticgliosarcomaacasereportandreviewoftheliterature
AT kanetkanjanapradit extraneuralmetastaticgliosarcomaacasereportandreviewoftheliterature