Estimating the transfer rates of bacterial plasmids with an adapted Luria-Delbrück fluctuation analysis.

To increase our basic understanding of the ecology and evolution of conjugative plasmids, we need reliable estimates of their rate of transfer between bacterial cells. Current assays to measure transfer rate are based on deterministic modeling frameworks. However, some cell numbers in these assays c...

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Bibliographic Details
Main Authors: Olivia Kosterlitz, Adamaris Muñiz Tirado, Claire Wate, Clint Elg, Ivana Bozic, Eva M Top, Benjamin Kerr
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-07-01
Series:PLoS Biology
Online Access:https://doi.org/10.1371/journal.pbio.3001732