CD44 expressed by myeloid cells promotes glioma invasion

CD44 expressed by myeloid cells promotes glioma invasion

Glioblastoma multiforme (GBM) is one of the most common and malignant brain tumors in adulthood with a median survival of only 15 months. This poor prognosis is related to GBM’s ability to extensively infiltrate the surrounding brain parenchyma resulting in diffuse spread of neoplastic cells in the...

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Bibliographic Details
Main Authors: Ekaterina L. Ivanova, Barbara Costa, Tanja Eisemann, Sabrina Lohr, Pavle Boskovic, Viktoria Eichwald, Jasmin Meckler, Manfred Jugold, Veronique Orian-Rousseau, Heike Peterziel, Peter Angel
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Oncology
Subjects:
glioblastoma
CD44
tumor microenvironment
microglia
TLR2
MMP9
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.969787/full

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