The Impact of Organised Screening Programs on Breast Cancer Stage at Diagnosis for Canadian Women Aged 40–49 and 50–59
The relationship between Canadian mammography screening practices for women 40–49 and breast cancer (BC) stage at diagnosis in women 40–49 and 50–59 years was assessed using data from the Canadian Cancer Registry, provincial/territorial screening practices, and screening information from the Canadia...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-08-01
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| Series: | Current Oncology |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1718-7729/29/8/444 |
| _version_ | 1797432284447506432 |
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| author | Anna N. Wilkinson Jean-Michel Billette Larry F. Ellison Michael A. Killip Nayaar Islam Jean M. Seely |
| author_facet | Anna N. Wilkinson Jean-Michel Billette Larry F. Ellison Michael A. Killip Nayaar Islam Jean M. Seely |
| author_sort | Anna N. Wilkinson |
| collection | DOAJ |
| description | The relationship between Canadian mammography screening practices for women 40–49 and breast cancer (BC) stage at diagnosis in women 40–49 and 50–59 years was assessed using data from the Canadian Cancer Registry, provincial/territorial screening practices, and screening information from the Canadian Community Health Survey. For the 2010 to 2017 period, women aged 40–49 were diagnosed with lesser relative proportions of stage I BC (35.7 vs. 45.3%; <i>p</i> < 0.001), but greater proportions of stage II (42.6 vs. 36.7%, <i>p</i> < 0.001) and III (17.3 vs. 13.1%, <i>p</i> < 0.001) compared to women 50–59. Stage IV was lower among women 40–49 than 50–59 (4.4% vs. 4.8%, <i>p</i> = 0.005). Jurisdictions with organised screening programs for women 40–49 with annual recall (screeners) were compared with those without (comparators). Women aged 40–49 in comparator jurisdictions had higher proportions of stages II (43.7% vs. 40.7%, <i>p</i> < 0.001), III (18.3% vs. 15.6%, <i>p</i> < 0.001) and IV (4.6% vs. 3.9%, <i>p</i> = 0.001) compared to their peers in screener jurisdictions. Based on screening practices for women aged 40–49, women aged 50–59 had higher proportions of stages II (37.2% vs. 36.0%, <i>p</i> = 0.003) and III (13.6% vs. 12.3%, <i>p</i> < 0.001) in the comparator versus screener groups. The results of this study can be used to reassess the optimum lower age for BC screening in Canada. |
| first_indexed | 2024-03-09T09:58:09Z |
| format | Article |
| id | doaj.art-3a28d12cee8c48f1b8f94050a4c26109 |
| institution | Directory Open Access Journal |
| issn | 1198-0052 1718-7729 |
| language | English |
| last_indexed | 2024-03-09T09:58:09Z |
| publishDate | 2022-08-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Current Oncology |
| spelling | doaj.art-3a28d12cee8c48f1b8f94050a4c261092023-12-01T23:35:33ZengMDPI AGCurrent Oncology1198-00521718-77292022-08-012985627564310.3390/curroncol29080444The Impact of Organised Screening Programs on Breast Cancer Stage at Diagnosis for Canadian Women Aged 40–49 and 50–59Anna N. Wilkinson0Jean-Michel Billette1Larry F. Ellison2Michael A. Killip3Nayaar Islam4Jean M. Seely5Department of Family Medicine, Faculty of Medicine, University of Ottawa, Ottawa, ON K1H 8L6, CanadaCentre for Population Health Data at Statistics Canada, Ottawa, ON K1A 0T6, CanadaCentre for Population Health Data at Statistics Canada, Ottawa, ON K1A 0T6, CanadaSchool of Medicine, University of Limerick, V94 T9PX Limerick, IrelandClinical Epidemiology Program, The Ottawa Hospital Research Institute, Ottawa, ON K1H 8L6, CanadaDepartment of Radiology, The Ottawa Hospital Research Institute, University of Ottawa, Ottawa, ON K1H 8L6, CanadaThe relationship between Canadian mammography screening practices for women 40–49 and breast cancer (BC) stage at diagnosis in women 40–49 and 50–59 years was assessed using data from the Canadian Cancer Registry, provincial/territorial screening practices, and screening information from the Canadian Community Health Survey. For the 2010 to 2017 period, women aged 40–49 were diagnosed with lesser relative proportions of stage I BC (35.7 vs. 45.3%; <i>p</i> < 0.001), but greater proportions of stage II (42.6 vs. 36.7%, <i>p</i> < 0.001) and III (17.3 vs. 13.1%, <i>p</i> < 0.001) compared to women 50–59. Stage IV was lower among women 40–49 than 50–59 (4.4% vs. 4.8%, <i>p</i> = 0.005). Jurisdictions with organised screening programs for women 40–49 with annual recall (screeners) were compared with those without (comparators). Women aged 40–49 in comparator jurisdictions had higher proportions of stages II (43.7% vs. 40.7%, <i>p</i> < 0.001), III (18.3% vs. 15.6%, <i>p</i> < 0.001) and IV (4.6% vs. 3.9%, <i>p</i> = 0.001) compared to their peers in screener jurisdictions. Based on screening practices for women aged 40–49, women aged 50–59 had higher proportions of stages II (37.2% vs. 36.0%, <i>p</i> = 0.003) and III (13.6% vs. 12.3%, <i>p</i> < 0.001) in the comparator versus screener groups. The results of this study can be used to reassess the optimum lower age for BC screening in Canada.https://www.mdpi.com/1718-7729/29/8/444breast cancerscreening mammographystage shiftregistriespreventionrecommendations |
| spellingShingle | Anna N. Wilkinson Jean-Michel Billette Larry F. Ellison Michael A. Killip Nayaar Islam Jean M. Seely The Impact of Organised Screening Programs on Breast Cancer Stage at Diagnosis for Canadian Women Aged 40–49 and 50–59 Current Oncology breast cancer screening mammography stage shift registries prevention recommendations |
| title | The Impact of Organised Screening Programs on Breast Cancer Stage at Diagnosis for Canadian Women Aged 40–49 and 50–59 |
| title_full | The Impact of Organised Screening Programs on Breast Cancer Stage at Diagnosis for Canadian Women Aged 40–49 and 50–59 |
| title_fullStr | The Impact of Organised Screening Programs on Breast Cancer Stage at Diagnosis for Canadian Women Aged 40–49 and 50–59 |
| title_full_unstemmed | The Impact of Organised Screening Programs on Breast Cancer Stage at Diagnosis for Canadian Women Aged 40–49 and 50–59 |
| title_short | The Impact of Organised Screening Programs on Breast Cancer Stage at Diagnosis for Canadian Women Aged 40–49 and 50–59 |
| title_sort | impact of organised screening programs on breast cancer stage at diagnosis for canadian women aged 40 49 and 50 59 |
| topic | breast cancer screening mammography stage shift registries prevention recommendations |
| url | https://www.mdpi.com/1718-7729/29/8/444 |
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