SELECTION CRITERIA OF COMPOUNDS FOR DEVELOPMENT OF HIGH-POTENT ANALGESICS AND OTHER CNS DRUGS

SELECTION CRITERIA OF COMPOUNDS FOR DEVELOPMENT OF HIGH-POTENT ANALGESICS AND OTHER CNS DRUGS

The global opioid crisis requires a paradigm shift in medical use of opioids, the development of methodology to reduce illicit drug use, and development of drug addiction treatment and antidotes. USA target program - HEAL Initiative is implemented under the scientific guidance of NIH with active par...

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Bibliographic Details
Main Authors:	A. V. Sosnov, F. M. Semchenko, V. N. Tohmahchi, A. A. Sosnova, M. I. Vlasov, A. S. Radilov, D. V. Krivorotov
Format:	Article
Language:	Russian
Published:	LLC Center of Pharmaceutical Analytics (LLC «CPHA») 2019-01-01
Series:	Разработка и регистрация лекарственных средств
Subjects:	анальгетик опиоид морфин олисеридин аналоги фентанила пролекарство солекарство опиоидный кризис морфиновый эквивалент терапевтический индекс коэффициент распределения фармакокинетика неинъекционная лекарственная форма антидот
Online Access:	https://www.pharmjournal.ru/jour/article/view/614

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