Artificial intelligence in estimating fractional flow reserve: a systematic literature review of techniques

Abstract Background Fractional Flow Reserve (FFR) is the gold standard for the functional evaluation of coronary arteries, which is effective in selecting patients for revascularization, avoiding unnecessary procedures, and reducing treatment costs. However, its use is limited due to invasiveness, h...

Full description

Bibliographic Details
Main Authors: Arefinia Farhad, Rabiei Reza, Hosseini Azamossadat, Ghaemian Ali, Roshanpoor Arash, Aria Mehrad, Khorrami Zahra
Format: Article
Language:English
Published: BMC 2023-08-01
Series:BMC Cardiovascular Disorders
Subjects:
Online Access:https://doi.org/10.1186/s12872-023-03447-w
_version_ 1797578313263218688
author Arefinia Farhad
Rabiei Reza
Hosseini Azamossadat
Ghaemian Ali
Roshanpoor Arash
Aria Mehrad
Khorrami Zahra
author_facet Arefinia Farhad
Rabiei Reza
Hosseini Azamossadat
Ghaemian Ali
Roshanpoor Arash
Aria Mehrad
Khorrami Zahra
author_sort Arefinia Farhad
collection DOAJ
description Abstract Background Fractional Flow Reserve (FFR) is the gold standard for the functional evaluation of coronary arteries, which is effective in selecting patients for revascularization, avoiding unnecessary procedures, and reducing treatment costs. However, its use is limited due to invasiveness, high cost, and complexity. Therefore, the non-invasive estimation of FFR using artificial intelligence (AI) methods is crucial. Objective This study aimed to identify the AI techniques used for FFR estimation and to explore the features of the studies that applied AI techniques in FFR estimation. Methods The present systematic review was conducted by searching five databases, PubMed, Scopus, Web of Science, IEEE, and Science Direct, based on the search strategy of each database. Results Five hundred seventy-three articles were extracted, and by applying the inclusion and exclusion criteria, twenty-five were finally selected for review. The findings revealed that AI methods, including Machine Learning (ML) and Deep Learning (DL), have been used to estimate the FFR. Conclusion This study shows that AI methods can be used non-invasively to estimate FFR, which can help physicians diagnose and treat coronary artery occlusion and provide significant clinical performance for patients.
first_indexed 2024-03-10T22:20:09Z
format Article
id doaj.art-3a2cba9346e648b79404d8f38271a40f
institution Directory Open Access Journal
issn 1471-2261
language English
last_indexed 2024-03-10T22:20:09Z
publishDate 2023-08-01
publisher BMC
record_format Article
series BMC Cardiovascular Disorders
spelling doaj.art-3a2cba9346e648b79404d8f38271a40f2023-11-19T12:18:21ZengBMCBMC Cardiovascular Disorders1471-22612023-08-0123111010.1186/s12872-023-03447-wArtificial intelligence in estimating fractional flow reserve: a systematic literature review of techniquesArefinia Farhad0Rabiei Reza1Hosseini Azamossadat2Ghaemian Ali3Roshanpoor Arash4Aria Mehrad5Khorrami Zahra6Department of Health Information Technology and Management, School of Allied Medical Sciences, Shahid Beheshti University of Medical SciencesDepartment of Health Information Technology and Management, School of Allied Medical Sciences, Shahid Beheshti University of Medical SciencesDepartment of Health Information Technology and Management, School of Allied Medical Sciences, Shahid Beheshti University of Medical SciencesCardiovascular Research Center, Mazandaran University of Medical SciencesDepartment of Computer Science, Sama Technical and Vocational Training College, Tehran Branch (Tehran), Islamic Azad University (IAU)Department of Information Technology and Computer Engineering and Ophthalmic Epidemiology Research Center, Azarbaijan Shahid Madani UniversityResearch Institute for Ophthalmology and Vision Science, Shahid Beheshti University of Medical SciencesAbstract Background Fractional Flow Reserve (FFR) is the gold standard for the functional evaluation of coronary arteries, which is effective in selecting patients for revascularization, avoiding unnecessary procedures, and reducing treatment costs. However, its use is limited due to invasiveness, high cost, and complexity. Therefore, the non-invasive estimation of FFR using artificial intelligence (AI) methods is crucial. Objective This study aimed to identify the AI techniques used for FFR estimation and to explore the features of the studies that applied AI techniques in FFR estimation. Methods The present systematic review was conducted by searching five databases, PubMed, Scopus, Web of Science, IEEE, and Science Direct, based on the search strategy of each database. Results Five hundred seventy-three articles were extracted, and by applying the inclusion and exclusion criteria, twenty-five were finally selected for review. The findings revealed that AI methods, including Machine Learning (ML) and Deep Learning (DL), have been used to estimate the FFR. Conclusion This study shows that AI methods can be used non-invasively to estimate FFR, which can help physicians diagnose and treat coronary artery occlusion and provide significant clinical performance for patients.https://doi.org/10.1186/s12872-023-03447-wMachine learningFractional Flow ReverseFunctional evaluation
spellingShingle Arefinia Farhad
Rabiei Reza
Hosseini Azamossadat
Ghaemian Ali
Roshanpoor Arash
Aria Mehrad
Khorrami Zahra
Artificial intelligence in estimating fractional flow reserve: a systematic literature review of techniques
BMC Cardiovascular Disorders
Machine learning
Fractional Flow Reverse
Functional evaluation
title Artificial intelligence in estimating fractional flow reserve: a systematic literature review of techniques
title_full Artificial intelligence in estimating fractional flow reserve: a systematic literature review of techniques
title_fullStr Artificial intelligence in estimating fractional flow reserve: a systematic literature review of techniques
title_full_unstemmed Artificial intelligence in estimating fractional flow reserve: a systematic literature review of techniques
title_short Artificial intelligence in estimating fractional flow reserve: a systematic literature review of techniques
title_sort artificial intelligence in estimating fractional flow reserve a systematic literature review of techniques
topic Machine learning
Fractional Flow Reverse
Functional evaluation
url https://doi.org/10.1186/s12872-023-03447-w
work_keys_str_mv AT arefiniafarhad artificialintelligenceinestimatingfractionalflowreserveasystematicliteraturereviewoftechniques
AT rabieireza artificialintelligenceinestimatingfractionalflowreserveasystematicliteraturereviewoftechniques
AT hosseiniazamossadat artificialintelligenceinestimatingfractionalflowreserveasystematicliteraturereviewoftechniques
AT ghaemianali artificialintelligenceinestimatingfractionalflowreserveasystematicliteraturereviewoftechniques
AT roshanpoorarash artificialintelligenceinestimatingfractionalflowreserveasystematicliteraturereviewoftechniques
AT ariamehrad artificialintelligenceinestimatingfractionalflowreserveasystematicliteraturereviewoftechniques
AT khorramizahra artificialintelligenceinestimatingfractionalflowreserveasystematicliteraturereviewoftechniques