Water Intake and Adiposity Outcomes among Overweight and Obese Individuals: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

Background: Water consumption is believed to be a key factor in weight management strategies, yet the existing literature on the subject yields inconsistent findings. To systematically assess the scientific evidence regarding the effect of water intake on adiposity, we conducted a systematic review...

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Main Authors: Qiao-Yi Chen, Jaewon Khil, NaNa Keum
Format: Article
Language:English
Published: MDPI AG 2024-03-01
Series:Nutrients
Subjects:
Online Access:https://www.mdpi.com/2072-6643/16/7/963
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author Qiao-Yi Chen
Jaewon Khil
NaNa Keum
author_facet Qiao-Yi Chen
Jaewon Khil
NaNa Keum
author_sort Qiao-Yi Chen
collection DOAJ
description Background: Water consumption is believed to be a key factor in weight management strategies, yet the existing literature on the subject yields inconsistent findings. To systematically assess the scientific evidence regarding the effect of water intake on adiposity, we conducted a systematic review and meta-analysis of randomized controlled trials (RCTs) among overweight and obese populations. Methods: PubMed and Embase were searched for relevant articles published up to December 2023. The summary weighted mean difference (WMD) and 95% confidence interval (CI) were estimated using the DerSimonian–Laird random-effects model. Results: In this meta-analysis of eight RCTs, interventions to promote water intake or to substitute water for other beverages as compared to the control group resulted in a summary WMD of −0.33 kg (95% CI = −1.75–1.08, <i>I</i><sup>2</sup> = 78%) for body weight, −0.23 kg/m<sup>2</sup> (95% CI = −0.55–0.09, <i>I</i><sup>2</sup> = 0%) for body mass index (BMI), and 0.05 cm (95% CI = −1.20–1.30, <i>I</i><sup>2</sup> = 40%) for waist circumference (WC). Among RCTs substituting water for artificially sweetened beverages, summary WMD was 1.82 kg (95% CI = 0.97–2.67, <i>I</i><sup>2</sup> = 0%) for body weight and 1.23 cm (95% CI = −0.03–2.48, <i>I</i><sup>2</sup> = 0%) for WC. Conversely, among RCTs substituting water for sugar-sweetened beverages, summary WMD was −0.81 kg (95% CI = −1.66–0.03, <i>I</i><sup>2</sup> = 2%) for body weight and −0.96 cm (95% CI = −2.06–0.13, <i>I</i><sup>2</sup> = 0%) for WC. Conclusions: In conclusion, water intake may not significantly impact adiposity among overweight and obese individuals. However, replacing sugar-sweetened beverages with water might offer a modest benefit in inducing weight loss.
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spelling doaj.art-3a3455059dfe484fb22486fa2641f9402024-04-12T13:24:14ZengMDPI AGNutrients2072-66432024-03-0116796310.3390/nu16070963Water Intake and Adiposity Outcomes among Overweight and Obese Individuals: A Systematic Review and Meta-Analysis of Randomized Controlled TrialsQiao-Yi Chen0Jaewon Khil1NaNa Keum2Department of Food Science and Biotechnology, Dongguk University, Goyang 10326, Republic of KoreaDepartment of Food Science and Biotechnology, Dongguk University, Goyang 10326, Republic of KoreaDepartment of Food Science and Biotechnology, Dongguk University, Goyang 10326, Republic of KoreaBackground: Water consumption is believed to be a key factor in weight management strategies, yet the existing literature on the subject yields inconsistent findings. To systematically assess the scientific evidence regarding the effect of water intake on adiposity, we conducted a systematic review and meta-analysis of randomized controlled trials (RCTs) among overweight and obese populations. Methods: PubMed and Embase were searched for relevant articles published up to December 2023. The summary weighted mean difference (WMD) and 95% confidence interval (CI) were estimated using the DerSimonian–Laird random-effects model. Results: In this meta-analysis of eight RCTs, interventions to promote water intake or to substitute water for other beverages as compared to the control group resulted in a summary WMD of −0.33 kg (95% CI = −1.75–1.08, <i>I</i><sup>2</sup> = 78%) for body weight, −0.23 kg/m<sup>2</sup> (95% CI = −0.55–0.09, <i>I</i><sup>2</sup> = 0%) for body mass index (BMI), and 0.05 cm (95% CI = −1.20–1.30, <i>I</i><sup>2</sup> = 40%) for waist circumference (WC). Among RCTs substituting water for artificially sweetened beverages, summary WMD was 1.82 kg (95% CI = 0.97–2.67, <i>I</i><sup>2</sup> = 0%) for body weight and 1.23 cm (95% CI = −0.03–2.48, <i>I</i><sup>2</sup> = 0%) for WC. Conversely, among RCTs substituting water for sugar-sweetened beverages, summary WMD was −0.81 kg (95% CI = −1.66–0.03, <i>I</i><sup>2</sup> = 2%) for body weight and −0.96 cm (95% CI = −2.06–0.13, <i>I</i><sup>2</sup> = 0%) for WC. Conclusions: In conclusion, water intake may not significantly impact adiposity among overweight and obese individuals. However, replacing sugar-sweetened beverages with water might offer a modest benefit in inducing weight loss.https://www.mdpi.com/2072-6643/16/7/963water intakeadipositysystematic reviewmeta-analysisrandomized controlled trialweight loss
spellingShingle Qiao-Yi Chen
Jaewon Khil
NaNa Keum
Water Intake and Adiposity Outcomes among Overweight and Obese Individuals: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Nutrients
water intake
adiposity
systematic review
meta-analysis
randomized controlled trial
weight loss
title Water Intake and Adiposity Outcomes among Overweight and Obese Individuals: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
title_full Water Intake and Adiposity Outcomes among Overweight and Obese Individuals: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
title_fullStr Water Intake and Adiposity Outcomes among Overweight and Obese Individuals: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
title_full_unstemmed Water Intake and Adiposity Outcomes among Overweight and Obese Individuals: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
title_short Water Intake and Adiposity Outcomes among Overweight and Obese Individuals: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
title_sort water intake and adiposity outcomes among overweight and obese individuals a systematic review and meta analysis of randomized controlled trials
topic water intake
adiposity
systematic review
meta-analysis
randomized controlled trial
weight loss
url https://www.mdpi.com/2072-6643/16/7/963
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AT jaewonkhil waterintakeandadiposityoutcomesamongoverweightandobeseindividualsasystematicreviewandmetaanalysisofrandomizedcontrolledtrials
AT nanakeum waterintakeandadiposityoutcomesamongoverweightandobeseindividualsasystematicreviewandmetaanalysisofrandomizedcontrolledtrials