Construction of diazepine-containing spiroindolines via annulation reaction of α-halogenated N-acylhydrazones and isatin-derived MBH carbonates

Construction of diazepine-containing spiroindolines via annulation reaction of α-halogenated N-acylhydrazones and isatin-derived MBH carbonates

A straightforward synthetic protocol for the efficient construction of diazepine-containing spiroindolines has been developed and proceeds through a by base-promoted annulation reaction of α-halogenated N-acylhydrazones and isatin-derived MBH carbonates. The reaction mechanism of this formal [4 + 3]...

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Bibliographic Details
Main Authors:	Xing Liu, Wenjing Shi, Jing Sun, Chao-Guo Yan
Format:	Article
Language:	English
Published:	Beilstein-Institut 2023-12-01
Series:	Beilstein Journal of Organic Chemistry
Subjects:	acylhydrazone annulation azepine mbh carbonate spirooxindole
Online Access:	https://doi.org/10.3762/bjoc.19.143

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