Effects of Supplementation with Bee Pollen and Propolis on Growth Performance and Serum Metabolites of Rabbits: A Meta-Analysis

The objective of this study was to evaluate the effects of bee pollen (BP) and propolis (PRO) supplementation on rabbits’ productive performance and serum metabolites through a meta-analysis. Sixteen peer-reviewed publications were included in the data set. The rabbit strains used in the studies inc...

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Main Authors: María Inés Sierra-Galicia, Raymundo Rodríguez-de Lara, José Felipe Orzuna-Orzuna, Alejandro Lara-Bueno, Rodolfo Ramírez-Valverde, Marianela Fallas-López
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Animals
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Online Access:https://www.mdpi.com/2076-2615/13/3/439
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Summary:The objective of this study was to evaluate the effects of bee pollen (BP) and propolis (PRO) supplementation on rabbits’ productive performance and serum metabolites through a meta-analysis. Sixteen peer-reviewed publications were included in the data set. The rabbit strains used in the studies included in the data set were New Zealand White, V-line, Rex, and V-line crosses. Weighted mean differences (WMD) between treatments supplemented with BP or PRO and control treatments were used to assess the magnitude of the effect. BP supplementation decreased (<i>p</i> < 0.001) daily feed intake (DFI) and feed conversion ratio (FCR); however, increased (<i>p</i> < 0.001) average daily gain (ADG) and hot carcass yield (HCY). PRO supplementation reduced DFI (<i>p</i> = 0.041) and FCR (<i>p</i> < 0.001), and increased ADG (<i>p</i> < 0.001) and HCY (<i>p</i> = 0.005). In blood serum, BP supplementation increased total antioxidant capacity (TAC; <i>p</i> = 0.002) and decreased serum creatinine concentration (<i>p</i> = 0.049). Likewise, decreased serum levels of aspartate aminotransferase (AST), alanine aminotransferase (ALT), and malondialdehyde (MDA) were detected in response to BP supplementation (<i>p</i> < 0.05). PRO supplementation increased the TAC in blood serum (<i>p</i> = 0.018); however, decreased serum concentrations of AST, ALT, and MDA were observed (<i>p</i> < 0.05). In conclusion, BP or PRO supplementation can be used as a natural growth promoter in rabbits, and both can also improve rabbits' antioxidant status. However, BP or PRO supplementation does not affect rabbits' renal or hepatic health status.
ISSN:2076-2615