Effects of Inappropriate Acetylsalicylic Acid Use on Non-fatal Bleedings

Aim:This study aims to assess of using asetylsalicyclic acid (ASA) on non-fatal major and minor bleeding events in patients with inappropriate, primary and secondary prevention groups.Methods:Nine thousand, six hundred and fifty-one patients were screened within a one-year period. Patients using ASA...

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Main Authors: Mustafa Öztürk, Oğuzhan Ekrem Turan
Format: Article
Language:English
Published: Galenos Yayinevi 2019-12-01
Series:Haseki Tıp Bülteni
Subjects:
Online Access: http://www.hasekidergisi.com/archives/archive-detail/article-preview/effects-of-nappropriate-acetylsalicylic-acid-use-o/31993
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author Mustafa Öztürk
Oğuzhan Ekrem Turan
author_facet Mustafa Öztürk
Oğuzhan Ekrem Turan
author_sort Mustafa Öztürk
collection DOAJ
description Aim:This study aims to assess of using asetylsalicyclic acid (ASA) on non-fatal major and minor bleeding events in patients with inappropriate, primary and secondary prevention groups.Methods:Nine thousand, six hundred and fifty-one patients were screened within a one-year period. Patients using ASA for primary and secondary prevention were recorded. A total of 736 patients using ASA were divided into three groups as inappropriate, appropriate primary and secondary prevention.Results:One hundred and two (14%) patients were using ASA inappropriately. The duration of ASA use was 82.9±71.3 months. Thirteen (1.8%) major (11 gastrointestinal, one intraocular, one intracranial) and 29 minor (3.9%) bleedings had occurred. Eleven (2.5%) major bleeding events had occurred in secondary prevention group and one (0.5%) in appropriate and one (1%) in inappropriate primary prevention group (p=0.16). Nineteen (4.4%) and 10 (5.1%) minor bleeding events were seen in appropriate and secondary prevention groups, respectively and there was no minor bleeding event occurred in inappropriate primary prevention group (p=0.078).Conclusion:Our study showed that inappropriate ASA use did not increase the risk of non-fatal major and minor bleeding events. It may be reasonable to consider that patients without a history of occlusive vascular disease are less prone to non-fatal bleeding events compared to those with occlusive vascular disease.
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spelling doaj.art-3a3d345103e34936b78371de6a7543f82023-02-15T16:10:39ZengGalenos YayineviHaseki Tıp Bülteni1302-00722147-26882019-12-0157439640410.4274/haseki.galenos.2019.513113049054Effects of Inappropriate Acetylsalicylic Acid Use on Non-fatal BleedingsMustafa Öztürk0Oğuzhan Ekrem Turan1 University of Health Sciences, Erzurum Training and Research Hospital, Clinic of Cardiology, Erzurum, Turkey Karadeniz Technical University Faculty of Medicine, Department of Cardiology, Trabzon, Turkey Aim:This study aims to assess of using asetylsalicyclic acid (ASA) on non-fatal major and minor bleeding events in patients with inappropriate, primary and secondary prevention groups.Methods:Nine thousand, six hundred and fifty-one patients were screened within a one-year period. Patients using ASA for primary and secondary prevention were recorded. A total of 736 patients using ASA were divided into three groups as inappropriate, appropriate primary and secondary prevention.Results:One hundred and two (14%) patients were using ASA inappropriately. The duration of ASA use was 82.9±71.3 months. Thirteen (1.8%) major (11 gastrointestinal, one intraocular, one intracranial) and 29 minor (3.9%) bleedings had occurred. Eleven (2.5%) major bleeding events had occurred in secondary prevention group and one (0.5%) in appropriate and one (1%) in inappropriate primary prevention group (p=0.16). Nineteen (4.4%) and 10 (5.1%) minor bleeding events were seen in appropriate and secondary prevention groups, respectively and there was no minor bleeding event occurred in inappropriate primary prevention group (p=0.078).Conclusion:Our study showed that inappropriate ASA use did not increase the risk of non-fatal major and minor bleeding events. It may be reasonable to consider that patients without a history of occlusive vascular disease are less prone to non-fatal bleeding events compared to those with occlusive vascular disease. http://www.hasekidergisi.com/archives/archive-detail/article-preview/effects-of-nappropriate-acetylsalicylic-acid-use-o/31993 acetylsalicylic acidprimary preventionnon-fatal bleeding
spellingShingle Mustafa Öztürk
Oğuzhan Ekrem Turan
Effects of Inappropriate Acetylsalicylic Acid Use on Non-fatal Bleedings
Haseki Tıp Bülteni
acetylsalicylic acid
primary prevention
non-fatal bleeding
title Effects of Inappropriate Acetylsalicylic Acid Use on Non-fatal Bleedings
title_full Effects of Inappropriate Acetylsalicylic Acid Use on Non-fatal Bleedings
title_fullStr Effects of Inappropriate Acetylsalicylic Acid Use on Non-fatal Bleedings
title_full_unstemmed Effects of Inappropriate Acetylsalicylic Acid Use on Non-fatal Bleedings
title_short Effects of Inappropriate Acetylsalicylic Acid Use on Non-fatal Bleedings
title_sort effects of inappropriate acetylsalicylic acid use on non fatal bleedings
topic acetylsalicylic acid
primary prevention
non-fatal bleeding
url http://www.hasekidergisi.com/archives/archive-detail/article-preview/effects-of-nappropriate-acetylsalicylic-acid-use-o/31993
work_keys_str_mv AT mustafaozturk effectsofinappropriateacetylsalicylicaciduseonnonfatalbleedings
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