Panuveitis in Sweet syndrome

Ocular manifestations of Sweet syndrome, or acute febrile neutrophilic dermatosis, are usually limited to the anterior segment. We report the case of a patient with bilateral panuveitis and retinal vasculitis associated with Sweet syndrome. A 45-year-old Asian female with an undiagnosed febrile illn...

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Main Authors: Kelvin Ngan, James C Y Leong, Helen Long
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2020-01-01
Series:Indian Journal of Ophthalmology
Subjects:
Online Access:http://www.ijo.in/article.asp?issn=0301-4738;year=2020;volume=68;issue=9;spage=2004;epage=2006;aulast=Ngan
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author Kelvin Ngan
James C Y Leong
Helen Long
author_facet Kelvin Ngan
James C Y Leong
Helen Long
author_sort Kelvin Ngan
collection DOAJ
description Ocular manifestations of Sweet syndrome, or acute febrile neutrophilic dermatosis, are usually limited to the anterior segment. We report the case of a patient with bilateral panuveitis and retinal vasculitis associated with Sweet syndrome. A 45-year-old Asian female with an undiagnosed febrile illness with rash presented with bilateral panuveitis with haemorrhagic occlusive retinal vasculitis. Skin biopsy confirmed Sweet Syndrome. Intraocular inflammation resolved with a combination of topical and systemic corticosteroids as well as intravenous cyclophosphamide, with resulting permanent severe right visual impairment. Although an uncommon condition, Sweet syndrome should be considered in any febrile patient with skin lesions and uveitis.
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spelling doaj.art-3a41425dcbd04e08b529ba3aed00de7b2022-12-21T19:04:49ZengWolters Kluwer Medknow PublicationsIndian Journal of Ophthalmology0301-47381998-36892020-01-016892004200610.4103/ijo.IJO_1667_19Panuveitis in Sweet syndromeKelvin NganJames C Y LeongHelen LongOcular manifestations of Sweet syndrome, or acute febrile neutrophilic dermatosis, are usually limited to the anterior segment. We report the case of a patient with bilateral panuveitis and retinal vasculitis associated with Sweet syndrome. A 45-year-old Asian female with an undiagnosed febrile illness with rash presented with bilateral panuveitis with haemorrhagic occlusive retinal vasculitis. Skin biopsy confirmed Sweet Syndrome. Intraocular inflammation resolved with a combination of topical and systemic corticosteroids as well as intravenous cyclophosphamide, with resulting permanent severe right visual impairment. Although an uncommon condition, Sweet syndrome should be considered in any febrile patient with skin lesions and uveitis.http://www.ijo.in/article.asp?issn=0301-4738;year=2020;volume=68;issue=9;spage=2004;epage=2006;aulast=Nganacute febrile neutrophilic dermatosispanuveitisretinal vasculitissweet syndromeuveitis
spellingShingle Kelvin Ngan
James C Y Leong
Helen Long
Panuveitis in Sweet syndrome
Indian Journal of Ophthalmology
acute febrile neutrophilic dermatosis
panuveitis
retinal vasculitis
sweet syndrome
uveitis
title Panuveitis in Sweet syndrome
title_full Panuveitis in Sweet syndrome
title_fullStr Panuveitis in Sweet syndrome
title_full_unstemmed Panuveitis in Sweet syndrome
title_short Panuveitis in Sweet syndrome
title_sort panuveitis in sweet syndrome
topic acute febrile neutrophilic dermatosis
panuveitis
retinal vasculitis
sweet syndrome
uveitis
url http://www.ijo.in/article.asp?issn=0301-4738;year=2020;volume=68;issue=9;spage=2004;epage=2006;aulast=Ngan
work_keys_str_mv AT kelvinngan panuveitisinsweetsyndrome
AT jamescyleong panuveitisinsweetsyndrome
AT helenlong panuveitisinsweetsyndrome