IRAG2 Interacts with IP<sub>3</sub>-Receptor Types 1, 2, and 3 and Regulates Intracellular Ca<sup>2+</sup> in Murine Pancreatic Acinar Cells

IRAG2 Interacts with IP<sub>3</sub>-Receptor Types 1, 2, and 3 and Regulates Intracellular Ca<sup>2+</sup> in Murine Pancreatic Acinar Cells

The inositol 1,4,5-triphosphate receptor-associated 2 (IRAG2) is also known as Jaw1 or lymphoid-restricted membrane protein (LRMP) and shares homology with the inositol 1,4,5-triphosphate receptor-associated cGMP kinase substrate 1 (IRAG1). IRAG1 interacts with inositol trisphosphate receptors (IP&l...

Full description

Bibliographic Details
Main Authors:	Sally Prüschenk, Michael Majer, Rainer Schreiber, Jens Schlossmann
Format:	Article
Language:	English
Published:	MDPI AG 2021-12-01
Series:	International Journal of Molecular Sciences
Subjects:	Ca<sup>2+</sup> signaling IP<sub>3</sub>R IRAG IRAG1 IRAG2 Jaw1
Online Access:	https://www.mdpi.com/1422-0067/22/24/13409

Similar Items

Function of IRAG2 Is Modulated by NO/cGMP in Murine Platelets
by: Sally Prüschenk, et al.
Published: (2022-06-01)

Loss of PKGIβ/IRAG1 Signaling Causes Anemia-Associated Splenomegaly
by: Michael Majer, et al.
Published: (2021-05-01)

Novel Functional Features of cGMP Substrate Proteins IRAG1 and IRAG2
by: Sally Prüschenk, et al.
Published: (2023-06-01)

IRAG1 Deficient Mice Develop PKG1β Dependent Pulmonary Hypertension
by: Siladitta Biswas, et al.
Published: (2020-10-01)

THE REALITY OF THE RELATIONSHIP BETWEEN AGRICULTURAL RESEARCH AND EXTENSION ORGANIZATIONS IN IRAQ
by: Anan Al-Ansari, et al.
Published: (2020-09-01)

LRMP inhibits cAMP potentiation of HCN4 channels by disrupting intramolecular signal transduction
by: Colin H Peters, et al.
Published: (2024-04-01)

Regulation of HCN Channels by Protein Interactions
by: Colin H. Peters, et al.
Published: (2022-06-01)

Structural Aspects of Pt(η<sup>3</sup>–P<sup>1</sup>C<sub>2</sub>X<sup>1</sup>C<sub>2</sub>P<sup>2</sup>)(Y) Derivative Types
by: Milan Melník, et al.
Published: (2023-09-01)

Agonist-Induced Ca<sup>2+</sup> Signaling in HEK-293-Derived Cells Expressing a Single IP<sub>3</sub> Receptor Isoform
by: Ekaterina N. Kochkina, et al.
Published: (2024-03-01)

A Ni(II) Coordination Polymer as a Multifunctional Luminescent Sensor for Detection of UO<sub>2</sub><sup>2+</sup>, Cr<sub>2</sub>O<sub>7</sub><sup>2−</sup>, CrO<sub>4</sub><sup>2−</sup> and Nitrofurantoin
by: Yun-Shan Xue, et al.
Published: (2023-06-01)

Catalytic Effect of CO<sub>2</sub> and H<sub>2</sub>O Molecules on <sup>•</sup>CH<sub>3</sub> + <sup>3</sup>O<sub>2</sub> Reaction
by: Mohamad Akbar Ali, et al.
Published: (2022-06-01)

Organomonophosphines in Pt(η<sup>3</sup>-X<sup>1</sup>X<sup>2</sup>X<sup>3</sup>)(PR<sub>3</sub>), (X = N<sup>1</sup>, N<sup>2</sup>, N<sup>3</sup>; S<sup>1</sup>, S<sup>2</sup>, S<sup>3</sup>; or Te<sup>1</sup>, Te<sup>2</sup>, Te<sup>3</sup>) Derivatives: Structural Aspects
by: Milan Melník, et al.
Published: (2023-06-01)

Initial Steps in the Reaction of H<sub>2</sub>O<sub>2</sub> with Fe<sup>2+</sup> and Fe<sup>3+</sup> Ions: Inconsistency in the Free Radical Theory
by: Mordechai L. Kremer
Published: (2023-02-01)

H<sub>2</sub>O<sub>2</sub>/Ca<sup>2+</sup>/Zn<sup>2+</sup> Complex Can Be Considered a “Collaborative Sensor” of the Mitochondrial Capacity?
by: Ester Sara Di Filippo, et al.
Published: (2022-02-01)

Preparation of Eu<sub>0.075</sub>Tb<sub>0.925</sub>-Metal Organic Framework as a Fluorescent Probe and Application in the Detection of Fe<sup>3+</sup> and Cr<sub>2</sub>O<sub>7</sub><sup>2−</sup>
by: Jie Yin, et al.
Published: (2021-11-01)

Enhanced Fluorescence Characteristics of SrAl<sub>2</sub>O<sub>4</sub>: Eu<sup>2+</sup>, Dy<sup>3+</sup> Phosphor by Co-Doping Gd<sup>3+</sup> and Anti-Counterfeiting Application
by: Peng Gao, et al.
Published: (2023-07-01)

Highly Luminous Ba<sub>2</sub>SiO<sub>4−δ</sub>N<sub>2/3δ</sub>:Eu<sup>2+</sup> Phosphor for NUV-LEDs: Origin of PL-Enhancement by N<sup>3−</sup>-Substitution
by: Donghyeon Kim, et al.
Published: (2020-04-01)

Resonant Ionic, Covalent Bond, and Steric Characteristics Present in <sup>1</sup>Σ<sub>u</sub><sup>+</sup> States of Li<sub>2</sub>
by: Michiko Ahn Furudate, et al.
Published: (2022-05-01)

The Complex Effects of PKM2 and PKM2:IP<sub>3</sub>R Disruption on Intracellular Ca<sup>2+</sup> Handling and Cellular Functions
by: Fernanda O. Lemos, et al.
Published: (2023-10-01)

Construction of a Two-Dimensional GO/Ti<sub>3</sub>C<sub>2</sub>T<sub>X</sub> Composite Membrane and Investigation of Mg<sup>2+</sup>/Li<sup>+</sup> Separation Performance
by: Zhenhua Feng, et al.
Published: (2023-10-01)

Biological Regulatory Network (BRN) Analysis and Molecular Docking Simulations to Probe the Modulation of IP<sub>3</sub>R Mediated Ca<sup>2+</sup> Signaling in Cancer
by: Humaira Ismatullah, et al.
Published: (2020-12-01)

Synthesis of Green-Emitting Gd<sub>2</sub>O<sub>2</sub>S:Pr<sup>3+</sup> Phosphor Nanoparticles and Fabrication of Translucent Gd<sub>2</sub>O<sub>2</sub>S:Pr<sup>3+</sup> Scintillation Ceramics
by: Zhigang Sun, et al.
Published: (2020-08-01)

Adsorption of Hydrated Pr<sup>3+</sup> and NH<sub>4</sub><sup>+</sup>/Mg<sup>2+</sup> Ions onto the (001) Surface of Montmorillonite: A DFT Analysis with Experimental Verification
by: Zhiqiang Zou, et al.
Published: (2022-11-01)

A Highly Selective and Sensitive Sequential Recognition Probe Zn<sup>2+</sup> and H<sub>2</sub>PO<sub>4</sub><sup>−</sup> Based on Chiral Thiourea Schiff Base
by: Shan Yang, et al.
Published: (2023-05-01)

Preparation of Ag-TiO<sub>2</sub>/Sr<sub>4</sub>Al<sub>14</sub>O<sub>25</sub>:Eu<sup>2+</sup>,Dy<sup>3+</sup> Photocatalyst on Phosphor Beads and Its Photoreaction Characteristics
by: Seong-Rak Eun, et al.
Published: (2021-02-01)

Pentacoordinate Carbon Atoms in a Ferrocene Dication Derivative—[Fe(Si<sub>2</sub>-<i>η</i><sup>5</sup>-C<sub>5</sub>H<sub>2</sub>)<sub>2</sub>]<sup>2+</sup>
by: Shilpa Shajan, et al.
Published: (2022-09-01)

Embracing [XY<sub>3</sub>]<i><sup>m–</sup></i> and [XY<sub>4</sub>]<i><sup>m–</sup></i> Anions in Salts of [M(bpy)<sub>3</sub>]<i><sup>q</sup></i><sup>+</sup>
by: Edwin C. Constable, et al.
Published: (2023-01-01)

Design, Synthesis, and Characterization of a Novel Blue-Green Long Afterglow BaYAl<sub>3</sub>O<sub>7</sub>:Eu<sup>2</sup><sup>+</sup>, Nd<sup>3</sup><sup>+</sup> Phosphor and Its Anti-Counterfeiting Application
by: Jiao Wu, et al.
Published: (2023-08-01)

Ambroxol-Enhanced Frequency and Amplitude of Beating Cilia Controlled by a Voltage-Gated Ca<sup>2+</sup> Channel, Cav1.2, via pH<sub>i</sub> Increase and [Cl<sup>−</sup>]<sub>i</sub> Decrease in the Lung Airway Epithelial Cells of Mice
by: Takashi Nakahari, et al.
Published: (2023-11-01)

Effect of Mixed Li<sup>+</sup>/Na<sup>+</sup>-ion Electrolyte on Electrochemical Performance of Na<sub>4</sub>Fe<sub>3</sub>(PO<sub>4</sub>)<sub>2</sub>P<sub>2</sub>O<sub>7</sub> in Hybrid Batteries
by: Nina V. Kosova, et al.
Published: (2019-04-01)

Research on Molecular Structure and Electronic Properties of Ln<sup>3+</sup> (Ce<sup>3+</sup>, Tb<sup>3+</sup>, Pr<sup>3+</sup>)/Li<sup>+</sup> and Eu<sup>2+</sup> Co-Doped Sr<sub>2</sub>Si<sub>5</sub>N<sub>8</sub> via DFT Calculation
by: Ziqian Yin, et al.
Published: (2021-03-01)

Synthesis, Photoluminescent Characteristics and Eu<sup>3+</sup>-Induced Phase Transitions in Sr<sub>3</sub>Zr<sub>2</sub>O<sub>7</sub>:Eu<sup>3+</sup> Red Phosphors
by: Nianmin Chen, et al.
Published: (2023-04-01)

Up-Conversion Luminescence and Optical Temperature Sensing Behaviour of Y<sub>2</sub>O<sub>3</sub>:Ho<sup>3+</sup>, Yb<sup>3+</sup> Phosphors
by: Vhahangwele Makumbane, et al.
Published: (2023-08-01)

Investigation of Exfoliation Efficiency of 6H-SiC Implanted Sequentially with He<sup>+</sup> and H<sub>2</sub><sup>+</sup> Ions
by: Guoqiang You, et al.
Published: (2022-04-01)

Spectroscopic Study of the Salicyladazine Derivative–UO<sub>2</sub><sup>2+</sup> Complex and Its Immobilization to Mesoporous Silica
by: Sujin Park, et al.
Published: (2019-05-01)

Tuning the Red-to-Green-Upconversion Luminescence Intensity Ratio of Na<sub>3</sub>ScF<sub>6</sub>: 20% Yb<sup>3+</sup>, 2% Er<sup>3+</sup> Particles by Changes in Size
by: Yongling Zhang, et al.
Published: (2023-03-01)

Simultaneous Removal of Hg<sup>0</sup> and H<sub>2</sub>S over a Regenerable Fe<sub>2</sub>O<sub>3</sub>/AC Catalyst
by: Junwei Wang, et al.
Published: (2022-03-01)

Smart Mn<sup>7+</sup> Sensing via Quenching on Dual Fluorescence of Eu<sup>3+</sup> Complex-Modified TiO<sub>2</sub> Nanoparticles
by: Wenbin Yang, et al.
Published: (2021-12-01)

First Terrestrial Occurrence of Kaitianite (Ti<sup>3+</sup><sub>2</sub>Ti<sup>4+</sup>O<sub>5</sub>) from the Upper Mantle beneath Mount Carmel, Israel
by: Chi Ma, et al.
Published: (2023-08-01)

The pH Value Control of Morphology and Luminescence Properties of Gd<sub>2</sub>O<sub>2</sub>S: Tb<sup>3+</sup> Phosphors
by: Peng Jiang, et al.
Published: (2022-01-01)