Aspirin’s effect on kinetic parameters of cells contributes to its role in reducing incidence of advanced colorectal adenomas, shown by a multiscale computational study
Aspirin intake has been shown to lead to significant protection against colorectal cancer, for example with an up to twofold reduction in colorectal adenoma incidence rates at higher doses. The mechanisms contributing to protection are not yet fully understood. While aspirin is an anti-inflammatory...
Main Authors: | Yifan Wang, C Richard Boland, Ajay Goel, Dominik Wodarz, Natalia L Komarova |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2022-04-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/71953 |
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