The Importance of Multimodality Imaging in the Diagnosis and Management of Patients with Infiltrative Cardiomyopathies: An Update
Infiltrative cardiomyopathies (ICMs) comprise a broad spectrum of inherited and acquired conditions (mainly amyloidosis, sarcoidosis, and hemochromatosis), where the progressive buildup of abnormal substances within the myocardium results in left ventricular hypertrophy and manifests as restrictive...
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MDPI AG
2021-02-01
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| Series: | Diagnostics |
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| Online Access: | https://www.mdpi.com/2075-4418/11/2/256 |
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| author | Radu Sascău Larisa Anghel Alexandra Clement Mădălina Bostan Rodica Radu Cristian Stătescu |
| author_facet | Radu Sascău Larisa Anghel Alexandra Clement Mădălina Bostan Rodica Radu Cristian Stătescu |
| author_sort | Radu Sascău |
| collection | DOAJ |
| description | Infiltrative cardiomyopathies (ICMs) comprise a broad spectrum of inherited and acquired conditions (mainly amyloidosis, sarcoidosis, and hemochromatosis), where the progressive buildup of abnormal substances within the myocardium results in left ventricular hypertrophy and manifests as restrictive physiology. Noninvasive multimodality imaging has gradually eliminated endomyocardial biopsy from the diagnostic workup of infiltrative cardiac deposition diseases. However, even with modern imaging techniques’ widespread availability, these pathologies persist in being largely under- or misdiagnosed. Considering the advent of novel, revolutionary pharmacotherapies for cardiac amyloidosis, the archetypal example of ICM, a standardized diagnostic approach is warranted. Therefore, this review aims to emphasize the importance of contemporary cardiac imaging in identifying specific ICM and improving outcomes via the prompt initiation of a targeted treatment. |
| first_indexed | 2024-03-09T05:16:50Z |
| format | Article |
| id | doaj.art-3a47d2b49c604671b1c94a25f7ff5d32 |
| institution | Directory Open Access Journal |
| issn | 2075-4418 |
| language | English |
| last_indexed | 2024-03-09T05:16:50Z |
| publishDate | 2021-02-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Diagnostics |
| spelling | doaj.art-3a47d2b49c604671b1c94a25f7ff5d322023-12-03T12:44:02ZengMDPI AGDiagnostics2075-44182021-02-0111225610.3390/diagnostics11020256The Importance of Multimodality Imaging in the Diagnosis and Management of Patients with Infiltrative Cardiomyopathies: An UpdateRadu Sascău0Larisa Anghel1Alexandra Clement2Mădălina Bostan3Rodica Radu4Cristian Stătescu5Internal Medicine Department, “Grigore T. Popa” University of Medicine and Pharmacy, 700503 Iași, RomaniaInternal Medicine Department, “Grigore T. Popa” University of Medicine and Pharmacy, 700503 Iași, RomaniaCardiology Department, Cardiovascular Diseases Institute “Prof. Dr. George I.M.Georgescu”, 700503 Iași, RomaniaInternal Medicine Department, “Grigore T. Popa” University of Medicine and Pharmacy, 700503 Iași, RomaniaInternal Medicine Department, “Grigore T. Popa” University of Medicine and Pharmacy, 700503 Iași, RomaniaInternal Medicine Department, “Grigore T. Popa” University of Medicine and Pharmacy, 700503 Iași, RomaniaInfiltrative cardiomyopathies (ICMs) comprise a broad spectrum of inherited and acquired conditions (mainly amyloidosis, sarcoidosis, and hemochromatosis), where the progressive buildup of abnormal substances within the myocardium results in left ventricular hypertrophy and manifests as restrictive physiology. Noninvasive multimodality imaging has gradually eliminated endomyocardial biopsy from the diagnostic workup of infiltrative cardiac deposition diseases. However, even with modern imaging techniques’ widespread availability, these pathologies persist in being largely under- or misdiagnosed. Considering the advent of novel, revolutionary pharmacotherapies for cardiac amyloidosis, the archetypal example of ICM, a standardized diagnostic approach is warranted. Therefore, this review aims to emphasize the importance of contemporary cardiac imaging in identifying specific ICM and improving outcomes via the prompt initiation of a targeted treatment.https://www.mdpi.com/2075-4418/11/2/256infiltrative cardiomyopathiesmultimodality imagingamyloidosissarcoidosishemochromatosis |
| spellingShingle | Radu Sascău Larisa Anghel Alexandra Clement Mădălina Bostan Rodica Radu Cristian Stătescu The Importance of Multimodality Imaging in the Diagnosis and Management of Patients with Infiltrative Cardiomyopathies: An Update Diagnostics infiltrative cardiomyopathies multimodality imaging amyloidosis sarcoidosis hemochromatosis |
| title | The Importance of Multimodality Imaging in the Diagnosis and Management of Patients with Infiltrative Cardiomyopathies: An Update |
| title_full | The Importance of Multimodality Imaging in the Diagnosis and Management of Patients with Infiltrative Cardiomyopathies: An Update |
| title_fullStr | The Importance of Multimodality Imaging in the Diagnosis and Management of Patients with Infiltrative Cardiomyopathies: An Update |
| title_full_unstemmed | The Importance of Multimodality Imaging in the Diagnosis and Management of Patients with Infiltrative Cardiomyopathies: An Update |
| title_short | The Importance of Multimodality Imaging in the Diagnosis and Management of Patients with Infiltrative Cardiomyopathies: An Update |
| title_sort | importance of multimodality imaging in the diagnosis and management of patients with infiltrative cardiomyopathies an update |
| topic | infiltrative cardiomyopathies multimodality imaging amyloidosis sarcoidosis hemochromatosis |
| url | https://www.mdpi.com/2075-4418/11/2/256 |
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