Cost-Utility of the eHealth Application ‘Oncokompas’, Supporting Incurably Ill Cancer Patients to Self-Manage Their Cancer-Related Symptoms: Results of a Randomized Controlled Trial
Evidence on the cost-effectiveness of eHealth in palliative care is scarce. Oncokompas, a fully automated behavioral intervention technology, aims to support self-management in cancer patients. This study aimed to assess the cost-utility of the eHealth application Oncokompas among incurably ill canc...
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2022-08-01
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| Series: | Current Oncology |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1718-7729/29/9/486 |
| _version_ | 1827662049059012608 |
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| author | Anouk S. Schuit Karen Holtmaat Veerle M. H. Coupé Simone E. J. Eerenstein Josée M. Zijlstra Corien Eeltink Annemarie Becker-Commissaris Lia van Zuylen Myra E. van Linde C. Willemien Menke-van der Houven van Oordt Dirkje W. Sommeijer Nol Verbeek Koop Bosscha Rishi Nandoe Tewarie Robert-Jan Sedee Remco de Bree Alexander de Graeff Filip de Vos Pim Cuijpers Irma M. Verdonck-de Leeuw Femke Jansen |
| author_facet | Anouk S. Schuit Karen Holtmaat Veerle M. H. Coupé Simone E. J. Eerenstein Josée M. Zijlstra Corien Eeltink Annemarie Becker-Commissaris Lia van Zuylen Myra E. van Linde C. Willemien Menke-van der Houven van Oordt Dirkje W. Sommeijer Nol Verbeek Koop Bosscha Rishi Nandoe Tewarie Robert-Jan Sedee Remco de Bree Alexander de Graeff Filip de Vos Pim Cuijpers Irma M. Verdonck-de Leeuw Femke Jansen |
| author_sort | Anouk S. Schuit |
| collection | DOAJ |
| description | Evidence on the cost-effectiveness of eHealth in palliative care is scarce. Oncokompas, a fully automated behavioral intervention technology, aims to support self-management in cancer patients. This study aimed to assess the cost-utility of the eHealth application Oncokompas among incurably ill cancer patients, compared to care as usual. In this randomized controlled trial, patients were randomized into the intervention group (access to Oncokompas) or the waiting-list control group (access after three months). Healthcare costs, productivity losses, and health status were measured at baseline and three months. Intervention costs were also taken into account. Non-parametric bootstrapping with 5000 replications was used to obtain 95% confidence intervals around the incremental costs and quality-adjusted life years (QALYs). A probabilistic approach was used because of the skewness of cost data. Altogether, 138 patients completed the baseline questionnaire and were randomly assigned to the intervention group (69) or the control group (69). In the base case analysis, mean total costs and mean total effects were non-significantly lower in the intervention group (−€806 and −0.01 QALYs). The probability that the intervention was more effective and less costly was 4%, whereas the probability of being less effective and less costly was 74%. Among patients with incurable cancer, Oncokompas does not impact incremental costs and seems slightly less effective in terms of QALYs, compared to care as usual. Future research on the costs of eHealth in palliative cancer care is warranted to assess the generalizability of the findings of this study. |
| first_indexed | 2024-03-10T00:19:40Z |
| format | Article |
| id | doaj.art-3a47e0cbe6194f9ca1f1a13d7602a847 |
| institution | Directory Open Access Journal |
| issn | 1198-0052 1718-7729 |
| language | English |
| last_indexed | 2024-03-10T00:19:40Z |
| publishDate | 2022-08-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Current Oncology |
| spelling | doaj.art-3a47e0cbe6194f9ca1f1a13d7602a8472023-11-23T15:45:36ZengMDPI AGCurrent Oncology1198-00521718-77292022-08-012996186620210.3390/curroncol29090486Cost-Utility of the eHealth Application ‘Oncokompas’, Supporting Incurably Ill Cancer Patients to Self-Manage Their Cancer-Related Symptoms: Results of a Randomized Controlled TrialAnouk S. Schuit0Karen Holtmaat1Veerle M. H. Coupé2Simone E. J. Eerenstein3Josée M. Zijlstra4Corien Eeltink5Annemarie Becker-Commissaris6Lia van Zuylen7Myra E. van Linde8C. Willemien Menke-van der Houven van Oordt9Dirkje W. Sommeijer10Nol Verbeek11Koop Bosscha12Rishi Nandoe Tewarie13Robert-Jan Sedee14Remco de Bree15Alexander de Graeff16Filip de Vos17Pim Cuijpers18Irma M. Verdonck-de Leeuw19Femke Jansen20Department Clinical, Neuro and Developmental Psychology, Vrije Universiteit Amsterdam, Van der Boechorststraat 7-9, 1081 BT Amsterdam, The NetherlandsDepartment Clinical, Neuro and Developmental Psychology, Vrije Universiteit Amsterdam, Van der Boechorststraat 7-9, 1081 BT Amsterdam, The NetherlandsCancer Treatment and Quality of Life, Cancer Center Amsterdam, 1081 HV Amsterdam, The NetherlandsCancer Treatment and Quality of Life, Cancer Center Amsterdam, 1081 HV Amsterdam, The NetherlandsCancer Treatment and Quality of Life, Cancer Center Amsterdam, 1081 HV Amsterdam, The NetherlandsCancer Treatment and Quality of Life, Cancer Center Amsterdam, 1081 HV Amsterdam, The NetherlandsCancer Treatment and Quality of Life, Cancer Center Amsterdam, 1081 HV Amsterdam, The NetherlandsCancer Treatment and Quality of Life, Cancer Center Amsterdam, 1081 HV Amsterdam, The NetherlandsCancer Treatment and Quality of Life, Cancer Center Amsterdam, 1081 HV Amsterdam, The NetherlandsCancer Treatment and Quality of Life, Cancer Center Amsterdam, 1081 HV Amsterdam, The NetherlandsCancer Treatment and Quality of Life, Cancer Center Amsterdam, 1081 HV Amsterdam, The NetherlandsDepartment of Oncology, St. Antonius Hospital, Soestwetering 1, 3543 AZ Utrecht, The NetherlandsDepartment of Surgery, Jeroen Bosch Hospital, Henri Dunantstraat 1, 5223 GZ Den Bosch, The NetherlandsDepartment of Neurosurgery, Haaglanden MC, Lijnbaan 32, 2512 VA The Hague, The NetherlandsDepartment of Otolaryngology, Head and Neck Surgery, Haaglanden MC, Lijnbaan 32, 2512 VA The Hague, The NetherlandsDepartment of Head and Neck Surgical Oncology, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX Utrecht, The NetherlandsDepartment of Medical Oncology, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX Utrecht, The NetherlandsDepartment of Medical Oncology, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX Utrecht, The NetherlandsDepartment Clinical, Neuro and Developmental Psychology, Vrije Universiteit Amsterdam, Van der Boechorststraat 7-9, 1081 BT Amsterdam, The NetherlandsDepartment Clinical, Neuro and Developmental Psychology, Vrije Universiteit Amsterdam, Van der Boechorststraat 7-9, 1081 BT Amsterdam, The NetherlandsCancer Treatment and Quality of Life, Cancer Center Amsterdam, 1081 HV Amsterdam, The NetherlandsEvidence on the cost-effectiveness of eHealth in palliative care is scarce. Oncokompas, a fully automated behavioral intervention technology, aims to support self-management in cancer patients. This study aimed to assess the cost-utility of the eHealth application Oncokompas among incurably ill cancer patients, compared to care as usual. In this randomized controlled trial, patients were randomized into the intervention group (access to Oncokompas) or the waiting-list control group (access after three months). Healthcare costs, productivity losses, and health status were measured at baseline and three months. Intervention costs were also taken into account. Non-parametric bootstrapping with 5000 replications was used to obtain 95% confidence intervals around the incremental costs and quality-adjusted life years (QALYs). A probabilistic approach was used because of the skewness of cost data. Altogether, 138 patients completed the baseline questionnaire and were randomly assigned to the intervention group (69) or the control group (69). In the base case analysis, mean total costs and mean total effects were non-significantly lower in the intervention group (−€806 and −0.01 QALYs). The probability that the intervention was more effective and less costly was 4%, whereas the probability of being less effective and less costly was 74%. Among patients with incurable cancer, Oncokompas does not impact incremental costs and seems slightly less effective in terms of QALYs, compared to care as usual. Future research on the costs of eHealth in palliative cancer care is warranted to assess the generalizability of the findings of this study.https://www.mdpi.com/1718-7729/29/9/486palliative careeHealthcost-utility analysiscost evaluationincurable cancerquality of life |
| spellingShingle | Anouk S. Schuit Karen Holtmaat Veerle M. H. Coupé Simone E. J. Eerenstein Josée M. Zijlstra Corien Eeltink Annemarie Becker-Commissaris Lia van Zuylen Myra E. van Linde C. Willemien Menke-van der Houven van Oordt Dirkje W. Sommeijer Nol Verbeek Koop Bosscha Rishi Nandoe Tewarie Robert-Jan Sedee Remco de Bree Alexander de Graeff Filip de Vos Pim Cuijpers Irma M. Verdonck-de Leeuw Femke Jansen Cost-Utility of the eHealth Application ‘Oncokompas’, Supporting Incurably Ill Cancer Patients to Self-Manage Their Cancer-Related Symptoms: Results of a Randomized Controlled Trial Current Oncology palliative care eHealth cost-utility analysis cost evaluation incurable cancer quality of life |
| title | Cost-Utility of the eHealth Application ‘Oncokompas’, Supporting Incurably Ill Cancer Patients to Self-Manage Their Cancer-Related Symptoms: Results of a Randomized Controlled Trial |
| title_full | Cost-Utility of the eHealth Application ‘Oncokompas’, Supporting Incurably Ill Cancer Patients to Self-Manage Their Cancer-Related Symptoms: Results of a Randomized Controlled Trial |
| title_fullStr | Cost-Utility of the eHealth Application ‘Oncokompas’, Supporting Incurably Ill Cancer Patients to Self-Manage Their Cancer-Related Symptoms: Results of a Randomized Controlled Trial |
| title_full_unstemmed | Cost-Utility of the eHealth Application ‘Oncokompas’, Supporting Incurably Ill Cancer Patients to Self-Manage Their Cancer-Related Symptoms: Results of a Randomized Controlled Trial |
| title_short | Cost-Utility of the eHealth Application ‘Oncokompas’, Supporting Incurably Ill Cancer Patients to Self-Manage Their Cancer-Related Symptoms: Results of a Randomized Controlled Trial |
| title_sort | cost utility of the ehealth application oncokompas supporting incurably ill cancer patients to self manage their cancer related symptoms results of a randomized controlled trial |
| topic | palliative care eHealth cost-utility analysis cost evaluation incurable cancer quality of life |
| url | https://www.mdpi.com/1718-7729/29/9/486 |
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