Value Frameworks for Vaccines: Which Dimensions Are Most Relevant?

In addition to more narrow criteria such as safety, effectiveness and cost-effectiveness, vaccines can also be evaluated based on broader criteria such as their economic impact, contribution to disease eradication objectives, caregiver aspects, financial protection offered, equity or social acceptab...

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Main Authors: Jeroen Luyten, Roselinde Kessels, Corinne Vandermeulen, Philippe Beutels
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Vaccines
Subjects:
Online Access:https://www.mdpi.com/2076-393X/8/4/628
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author Jeroen Luyten
Roselinde Kessels
Corinne Vandermeulen
Philippe Beutels
author_facet Jeroen Luyten
Roselinde Kessels
Corinne Vandermeulen
Philippe Beutels
author_sort Jeroen Luyten
collection DOAJ
description In addition to more narrow criteria such as safety, effectiveness and cost-effectiveness, vaccines can also be evaluated based on broader criteria such as their economic impact, contribution to disease eradication objectives, caregiver aspects, financial protection offered, equity or social acceptability. We summarize a survey executed in a sample of the population (<i>n</i> = 1000) in Flanders, Belgium, in which we investigated support for using these broader criteria to evaluate vaccines for funding decisions. By means of both favourable and unfavourable framings of a hypothetical vaccine across 40 value dimensions, we find support for the view that people indeed consider a broad range of medical and socio-economic criteria relevant. Several of these are not incorporated in standard evaluation frameworks for vaccines. The different results we find for different framings highlight the importance of developing a consistent a priori value framework for vaccine evaluation, rather than evaluating vaccines on an ad hoc basis.
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spelling doaj.art-3a483e535f3f4052ad76611695c722a82023-11-20T18:48:08ZengMDPI AGVaccines2076-393X2020-10-018462810.3390/vaccines8040628Value Frameworks for Vaccines: Which Dimensions Are Most Relevant?Jeroen Luyten0Roselinde Kessels1Corinne Vandermeulen2Philippe Beutels3KU Leuven, Department of Public Health and Primary Care, Leuven Institute for Healthcare Policy, Kapucijnenvoer 35, PO 7001, 3000 Leuven, BelgiumDepartment of Data Analytics and Digitalization, Maastricht University, P.O. Box 616, 6200 MD Maastricht, The NetherlandsKU Leuven, Department of Public Health and Primary Care, Leuven University Vaccinology Centre, Kapucijnenvoer 35, PO 7001, 3000 Leuven, BelgiumCentre for Health Economics Research and Modelling Infectious Diseases, Vaccine and Infectious Disease Institute, University of Antwerp, Universiteitsplein 1, 2610 Wilrijk, BelgiumIn addition to more narrow criteria such as safety, effectiveness and cost-effectiveness, vaccines can also be evaluated based on broader criteria such as their economic impact, contribution to disease eradication objectives, caregiver aspects, financial protection offered, equity or social acceptability. We summarize a survey executed in a sample of the population (<i>n</i> = 1000) in Flanders, Belgium, in which we investigated support for using these broader criteria to evaluate vaccines for funding decisions. By means of both favourable and unfavourable framings of a hypothetical vaccine across 40 value dimensions, we find support for the view that people indeed consider a broad range of medical and socio-economic criteria relevant. Several of these are not incorporated in standard evaluation frameworks for vaccines. The different results we find for different framings highlight the importance of developing a consistent a priori value framework for vaccine evaluation, rather than evaluating vaccines on an ad hoc basis.https://www.mdpi.com/2076-393X/8/4/628vaccine evaluationhealth technology assessmentevaluation spacepublic preferencespublic involvement
spellingShingle Jeroen Luyten
Roselinde Kessels
Corinne Vandermeulen
Philippe Beutels
Value Frameworks for Vaccines: Which Dimensions Are Most Relevant?
Vaccines
vaccine evaluation
health technology assessment
evaluation space
public preferences
public involvement
title Value Frameworks for Vaccines: Which Dimensions Are Most Relevant?
title_full Value Frameworks for Vaccines: Which Dimensions Are Most Relevant?
title_fullStr Value Frameworks for Vaccines: Which Dimensions Are Most Relevant?
title_full_unstemmed Value Frameworks for Vaccines: Which Dimensions Are Most Relevant?
title_short Value Frameworks for Vaccines: Which Dimensions Are Most Relevant?
title_sort value frameworks for vaccines which dimensions are most relevant
topic vaccine evaluation
health technology assessment
evaluation space
public preferences
public involvement
url https://www.mdpi.com/2076-393X/8/4/628
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