Plakofuranolactone as a Quorum Quenching Agent from the Indonesian Sponge Plakortis cf. lita

Plakofuranolactone as a Quorum Quenching Agent from the Indonesian Sponge Plakortis cf. lita

There is an urgent need for novel strategies to fight drug resistance and multi-drug resistance. As an alternative to the classic antibiotic therapy, attenuation of the bacteria virulence affecting their Quorum sensing (QS) system is a promising approach. Quorum sensing (QS) is a genetic regulation...

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Bibliographic Details
Main Authors: Valeria Costantino, Gerardo Della Sala, Kumar Saurav, Roberta Teta, Rinat Bar-Shalom, Alfonso Mangoni, Laura Steindler
Format: Article
Language:English
Published: MDPI AG 2017-02-01
Series:Marine Drugs
Subjects:
antibacterial from marine sponges
antivirulence lead compounds
quorum sensing system
plakofuranolactone
quorum quenching activity
marine sponges
Plakortis lita
Pseudomonas aeruginosa
reporter gene assays
Online Access:http://www.mdpi.com/1660-3397/15/3/59

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http://www.mdpi.com/1660-3397/15/3/59

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