The Associations of Vitamin D with Ovarian Reserve Markers and Depression: A Narrative Literature Review
Since the identification of vitamin D receptors in both the female reproductive tract and the central nervous system, further data have shown that vitamin D is involved in the processes of reproductive and mental health. This paper reviews current research on the associations of vitamin D with ovari...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-12-01
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| Series: | Nutrients |
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| Online Access: | https://www.mdpi.com/2072-6643/16/1/96 |
| _version_ | 1797358318028587008 |
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| author | Gyun-Ho Jeon |
| author_facet | Gyun-Ho Jeon |
| author_sort | Gyun-Ho Jeon |
| collection | DOAJ |
| description | Since the identification of vitamin D receptors in both the female reproductive tract and the central nervous system, further data have shown that vitamin D is involved in the processes of reproductive and mental health. This paper reviews current research on the associations of vitamin D with ovarian reserve markers and depression and discusses the potential role of vitamin D in their relationships. There have been numerous studies reporting that vitamin D was significantly related to ovarian reserve markers and depression in basic or clinical research, but some observational and interventional clinical studies have shown inconsistent results. Nevertheless, recent meta-analyses of interventional studies have provided promising results showing that vitamin D supplementation significantly improves ovarian reserve metrics, especially in a subgroup of women with normal or diminished ovarian reserve, and decreases depressive symptoms and risk. The demonstration of an association of vitamin D with both ovarian reserve and depression could suggest that vitamin D may be another important key in explaining female reproductive depression. Larger-scale studies in standardized settings will be needed in order to gain further insight into the role of vitamin D in female reproduction and depression. |
| first_indexed | 2024-03-08T15:00:11Z |
| format | Article |
| id | doaj.art-3a4db32501c74ea7a614332a46b36e23 |
| institution | Directory Open Access Journal |
| issn | 2072-6643 |
| language | English |
| last_indexed | 2024-03-08T15:00:11Z |
| publishDate | 2023-12-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Nutrients |
| spelling | doaj.art-3a4db32501c74ea7a614332a46b36e232024-01-10T15:05:31ZengMDPI AGNutrients2072-66432023-12-011619610.3390/nu16010096The Associations of Vitamin D with Ovarian Reserve Markers and Depression: A Narrative Literature ReviewGyun-Ho Jeon0Department of Obstetrics and Gynecology, Haeundae Paik Hospital, Inje University School of Medicine, Busan 48108, Republic of KoreaSince the identification of vitamin D receptors in both the female reproductive tract and the central nervous system, further data have shown that vitamin D is involved in the processes of reproductive and mental health. This paper reviews current research on the associations of vitamin D with ovarian reserve markers and depression and discusses the potential role of vitamin D in their relationships. There have been numerous studies reporting that vitamin D was significantly related to ovarian reserve markers and depression in basic or clinical research, but some observational and interventional clinical studies have shown inconsistent results. Nevertheless, recent meta-analyses of interventional studies have provided promising results showing that vitamin D supplementation significantly improves ovarian reserve metrics, especially in a subgroup of women with normal or diminished ovarian reserve, and decreases depressive symptoms and risk. The demonstration of an association of vitamin D with both ovarian reserve and depression could suggest that vitamin D may be another important key in explaining female reproductive depression. Larger-scale studies in standardized settings will be needed in order to gain further insight into the role of vitamin D in female reproduction and depression.https://www.mdpi.com/2072-6643/16/1/96vitamin Dovarian reserveanti-Müllerian hormonedepressionreproductioncentral nervous system |
| spellingShingle | Gyun-Ho Jeon The Associations of Vitamin D with Ovarian Reserve Markers and Depression: A Narrative Literature Review Nutrients vitamin D ovarian reserve anti-Müllerian hormone depression reproduction central nervous system |
| title | The Associations of Vitamin D with Ovarian Reserve Markers and Depression: A Narrative Literature Review |
| title_full | The Associations of Vitamin D with Ovarian Reserve Markers and Depression: A Narrative Literature Review |
| title_fullStr | The Associations of Vitamin D with Ovarian Reserve Markers and Depression: A Narrative Literature Review |
| title_full_unstemmed | The Associations of Vitamin D with Ovarian Reserve Markers and Depression: A Narrative Literature Review |
| title_short | The Associations of Vitamin D with Ovarian Reserve Markers and Depression: A Narrative Literature Review |
| title_sort | associations of vitamin d with ovarian reserve markers and depression a narrative literature review |
| topic | vitamin D ovarian reserve anti-Müllerian hormone depression reproduction central nervous system |
| url | https://www.mdpi.com/2072-6643/16/1/96 |
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