Protective Effect of Morocco Carob Honey Against Lead-Induced Anemia and Hepato-Renal Toxicity
Background/Aims: Natural honey has many biological activities including protective effect against toxic materials. The aim of this study was to evaluate the protective effect of carob honey against lead-induced hepato-renal toxicity and lead-induced anemia in rabbits. Methods: Twenty four male rabbi...
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| Format: | Article |
| Language: | English |
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Cell Physiol Biochem Press GmbH & Co KG
2016-06-01
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| Series: | Cellular Physiology and Biochemistry |
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| Online Access: | http://www.karger.com/Article/FullText/445610 |
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| author | Aicha Fassi Fihri Noori S. Al-Waili Redouan El-Haskoury Meryem Bakour Afaf Amarti Mohammad J. Ansari Badiaa Lyoussi |
| author_facet | Aicha Fassi Fihri Noori S. Al-Waili Redouan El-Haskoury Meryem Bakour Afaf Amarti Mohammad J. Ansari Badiaa Lyoussi |
| author_sort | Aicha Fassi Fihri |
| collection | DOAJ |
| description | Background/Aims: Natural honey has many biological activities including protective effect against toxic materials. The aim of this study was to evaluate the protective effect of carob honey against lead-induced hepato-renal toxicity and lead-induced anemia in rabbits. Methods: Twenty four male rabbits were allocated into four groups six rabbits each; group 1: control group, received distilled water (0.1 ml / kg.b.wt /daily); group 2: received oral lead acetate (2 g/kg.b.wt/daily); group 3: treated with oral honey (1g /kg.b.wt/daily) and oral lead (2 g/kg.b.wt/daily), and group 4: received oral honey (1 g/kg.b.wt/daily). Honey and lead were given daily during 24 days of experimentation. Laboratory tests and histopathological evaluations of kidneys were done. Results: Oral administration of lead induced hepatic and kidney injury and caused anemia during three weeks of the exposure. Treatment with honey prevented hepato-renal lead toxicity and ameliorated lead-induced anemia when honey was given to animals during lead exposure. Conclusion: It might be concluded that honey has a protective effect against lead-induced blood, hepatic and renal toxic effects. |
| first_indexed | 2024-12-11T06:10:26Z |
| format | Article |
| id | doaj.art-3a523a6218d1477cb71c4ab7a3bfa36f |
| institution | Directory Open Access Journal |
| issn | 1015-8987 1421-9778 |
| language | English |
| last_indexed | 2024-12-11T06:10:26Z |
| publishDate | 2016-06-01 |
| publisher | Cell Physiol Biochem Press GmbH & Co KG |
| record_format | Article |
| series | Cellular Physiology and Biochemistry |
| spelling | doaj.art-3a523a6218d1477cb71c4ab7a3bfa36f2022-12-22T01:18:09ZengCell Physiol Biochem Press GmbH & Co KGCellular Physiology and Biochemistry1015-89871421-97782016-06-0139111512210.1159/000445610445610Protective Effect of Morocco Carob Honey Against Lead-Induced Anemia and Hepato-Renal ToxicityAicha Fassi FihriNoori S. Al-WailiRedouan El-HaskouryMeryem BakourAfaf AmartiMohammad J. AnsariBadiaa LyoussiBackground/Aims: Natural honey has many biological activities including protective effect against toxic materials. The aim of this study was to evaluate the protective effect of carob honey against lead-induced hepato-renal toxicity and lead-induced anemia in rabbits. Methods: Twenty four male rabbits were allocated into four groups six rabbits each; group 1: control group, received distilled water (0.1 ml / kg.b.wt /daily); group 2: received oral lead acetate (2 g/kg.b.wt/daily); group 3: treated with oral honey (1g /kg.b.wt/daily) and oral lead (2 g/kg.b.wt/daily), and group 4: received oral honey (1 g/kg.b.wt/daily). Honey and lead were given daily during 24 days of experimentation. Laboratory tests and histopathological evaluations of kidneys were done. Results: Oral administration of lead induced hepatic and kidney injury and caused anemia during three weeks of the exposure. Treatment with honey prevented hepato-renal lead toxicity and ameliorated lead-induced anemia when honey was given to animals during lead exposure. Conclusion: It might be concluded that honey has a protective effect against lead-induced blood, hepatic and renal toxic effects.http://www.karger.com/Article/FullText/445610LeadHoneyKidneyLiverAntioxidantHemoglobin |
| spellingShingle | Aicha Fassi Fihri Noori S. Al-Waili Redouan El-Haskoury Meryem Bakour Afaf Amarti Mohammad J. Ansari Badiaa Lyoussi Protective Effect of Morocco Carob Honey Against Lead-Induced Anemia and Hepato-Renal Toxicity Cellular Physiology and Biochemistry Lead Honey Kidney Liver Antioxidant Hemoglobin |
| title | Protective Effect of Morocco Carob Honey Against Lead-Induced Anemia and Hepato-Renal Toxicity |
| title_full | Protective Effect of Morocco Carob Honey Against Lead-Induced Anemia and Hepato-Renal Toxicity |
| title_fullStr | Protective Effect of Morocco Carob Honey Against Lead-Induced Anemia and Hepato-Renal Toxicity |
| title_full_unstemmed | Protective Effect of Morocco Carob Honey Against Lead-Induced Anemia and Hepato-Renal Toxicity |
| title_short | Protective Effect of Morocco Carob Honey Against Lead-Induced Anemia and Hepato-Renal Toxicity |
| title_sort | protective effect of morocco carob honey against lead induced anemia and hepato renal toxicity |
| topic | Lead Honey Kidney Liver Antioxidant Hemoglobin |
| url | http://www.karger.com/Article/FullText/445610 |
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