An exploratory study of cell stiffness as a mechanical label-free biomarker across multiple musculoskeletal sarcoma cells

An exploratory study of cell stiffness as a mechanical label-free biomarker across multiple musculoskeletal sarcoma cells

Abstract Background Cancer cells are characterized by changes in cell cytoskeletal architecture and stiffness. Despite advances in understanding the molecular mechanisms of musculoskeletal cancers, the corresponding cellular mechanical properties remain largely unexplored. The aim of this study was...

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Bibliographic Details
Main Authors: Cyril Daniel, Frank Traub, Saskia Sachsenmaier, Rosa Riester, Moritz Mederake, Christian Konrads, Marina Danalache
Format: Article
Language:English
Published: BMC 2023-09-01
Series:BMC Cancer
Subjects:
Cancer
Musculoskeletal sarcomas
Atomic force microscopy
Stiffness
Biomarker
Cytoskeleton
Online Access:https://doi.org/10.1186/s12885-023-11375-3

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