Lactobacillus casei Strain Shirota Ameliorates Dextran Sulfate Sodium-Induced Colitis in Mice by Increasing Taurine-Conjugated Bile Acids and Inhibiting NF-κB Signaling via Stabilization of IκBα

Lactobacillus casei Strain Shirota Ameliorates Dextran Sulfate Sodium-Induced Colitis in Mice by Increasing Taurine-Conjugated Bile Acids and Inhibiting NF-κB Signaling via Stabilization of IκBα

Inflammatory bowel disease (IBD) is a chronic progressive intestinal inflammatory disease, characterized by an altered gut microbiota composition and accompanying alterations in circulatory bile acids. Increasing evidence supports the beneficial effect of probiotics intake on health. Introduction of...

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Bibliographic Details
Main Authors: Wing-Yan Wong, Brandon Dow Chan, Tung-Ting Sham, Magnolia Muk-Lan Lee, Chi-On Chan, Chung-Ting Chau, Daniel Kam-Wah Mok, Yiu-Wa Kwan, William Chi-Shing Tai
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-04-01
Series:Frontiers in Nutrition
Subjects:
probiotics
inflammatory bowel disease
Lactobacillus casei strain Shirota
gut microbiota
bile acids
DSS-induced acute colitis
Online Access:https://www.frontiersin.org/articles/10.3389/fnut.2022.816836/full

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