Psychometric Properties of the HADS Measure of Anxiety and Depression Among Multiple Sclerosis Patients in Croatia

Depression and anxiety are common complaints in patients with multiple sclerosis (MS). The study objective was to investigate the factor structure, internal consistency, and correlates of the Croatian version of the Hospital Anxiety and Depression Scale (HADS) in patients with MS. A total of 179 pat...

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Main Authors: Ana Jerković, Ana Proroković, Meri Matijaca, Jelena Vuko, Ana Poljičanin, Angela Mastelić, Ana Ćurković Katić, Vana Košta, Lea Kustura, Krešimir Dolić, Zoran Ðogaš, Maja Rogić Vidaković
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-11-01
Series:Frontiers in Psychology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fpsyg.2021.794353/full
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author Ana Jerković
Ana Proroković
Meri Matijaca
Jelena Vuko
Ana Poljičanin
Ana Poljičanin
Angela Mastelić
Ana Ćurković Katić
Vana Košta
Lea Kustura
Krešimir Dolić
Zoran Ðogaš
Zoran Ðogaš
Maja Rogić Vidaković
author_facet Ana Jerković
Ana Proroković
Meri Matijaca
Jelena Vuko
Ana Poljičanin
Ana Poljičanin
Angela Mastelić
Ana Ćurković Katić
Vana Košta
Lea Kustura
Krešimir Dolić
Zoran Ðogaš
Zoran Ðogaš
Maja Rogić Vidaković
author_sort Ana Jerković
collection DOAJ
description Depression and anxiety are common complaints in patients with multiple sclerosis (MS). The study objective was to investigate the factor structure, internal consistency, and correlates of the Croatian version of the Hospital Anxiety and Depression Scale (HADS) in patients with MS. A total of 179 patients with MS and 999 controls were included in the online survey. All subjects completed the HADS and self-administered questionnaires capturing information of demographic, education level, disease-related variables, and the Multiple Sclerosis Impact Scale-29 (MSIS-29). Psychometric properties were examined by estimating the validity, reliability, and factor structure of the HADS in patients with MS. The two HADS subscales (anxiety and depression) had excellent internal consistencies (Cronbach’s α value 0.82–0.83), and factor analysis confirmed a two-factor structure. The convergent validity of the HADS subscales appeared to be good due to the significant correlations between HADS and MSIS-29. Receiver operating characteristic (ROC) analysis indicates that the HADS subscales have a significant diagnostic validity for group differentiation. Hierarchical regression analysis using MSIS-29 subscales as criterion variables showed consistent evidence for the incremental validity of the HADS. The HADS is a reliable and valid self-assessment scale in patients with MS and is suggested to be used in clinical monitoring of the psychiatric and psychological status of patients with MS.
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spelling doaj.art-3a53a085eac44fe6a273bf9b24fc61b82022-12-21T20:34:06ZengFrontiers Media S.A.Frontiers in Psychology1664-10782021-11-011210.3389/fpsyg.2021.794353794353Psychometric Properties of the HADS Measure of Anxiety and Depression Among Multiple Sclerosis Patients in CroatiaAna Jerković0Ana Proroković1Meri Matijaca2Jelena Vuko3Ana Poljičanin4Ana Poljičanin5Angela Mastelić6Ana Ćurković Katić7Vana Košta8Lea Kustura9Krešimir Dolić10Zoran Ðogaš11Zoran Ðogaš12Maja Rogić Vidaković13Laboratory for Human and Experimental Neurophysiology, Department of Neuroscience, School of Medicine, University of Split, Split, CroatiaDepartment of Psychology, University of Zadar, Zadar, CroatiaDepartment of Neurology, University Hospital of Split, Split, CroatiaDepartment of Psychology, University of Zadar, Zadar, CroatiaInstitute of Physical Medicine and Rehabilitation with Rheumatology, University Hospital of Split, Split, CroatiaDepartment for Health Studies, University of Split, Split, CroatiaDepartment of Medical Chemistry and Biochemistry, University of Split School of Medicine, Split, CroatiaDepartment of Neurology, University Hospital of Split, Split, CroatiaDepartment of Neurology, University Hospital of Split, Split, CroatiaDepartment Psychiatry, University Hospital of Split, Split, CroatiaDepartment of Radiology, University Hospital of Split, Split, CroatiaLaboratory for Human and Experimental Neurophysiology, Department of Neuroscience, School of Medicine, University of Split, Split, CroatiaSleep Medical Center, University of Split, Split, CroatiaLaboratory for Human and Experimental Neurophysiology, Department of Neuroscience, School of Medicine, University of Split, Split, CroatiaDepression and anxiety are common complaints in patients with multiple sclerosis (MS). The study objective was to investigate the factor structure, internal consistency, and correlates of the Croatian version of the Hospital Anxiety and Depression Scale (HADS) in patients with MS. A total of 179 patients with MS and 999 controls were included in the online survey. All subjects completed the HADS and self-administered questionnaires capturing information of demographic, education level, disease-related variables, and the Multiple Sclerosis Impact Scale-29 (MSIS-29). Psychometric properties were examined by estimating the validity, reliability, and factor structure of the HADS in patients with MS. The two HADS subscales (anxiety and depression) had excellent internal consistencies (Cronbach’s α value 0.82–0.83), and factor analysis confirmed a two-factor structure. The convergent validity of the HADS subscales appeared to be good due to the significant correlations between HADS and MSIS-29. Receiver operating characteristic (ROC) analysis indicates that the HADS subscales have a significant diagnostic validity for group differentiation. Hierarchical regression analysis using MSIS-29 subscales as criterion variables showed consistent evidence for the incremental validity of the HADS. The HADS is a reliable and valid self-assessment scale in patients with MS and is suggested to be used in clinical monitoring of the psychiatric and psychological status of patients with MS.https://www.frontiersin.org/articles/10.3389/fpsyg.2021.794353/fullHospital Anxiety and Depression Scale (HADS)psychometricsdepressionmultiple sclerosisanxiety
spellingShingle Ana Jerković
Ana Proroković
Meri Matijaca
Jelena Vuko
Ana Poljičanin
Ana Poljičanin
Angela Mastelić
Ana Ćurković Katić
Vana Košta
Lea Kustura
Krešimir Dolić
Zoran Ðogaš
Zoran Ðogaš
Maja Rogić Vidaković
Psychometric Properties of the HADS Measure of Anxiety and Depression Among Multiple Sclerosis Patients in Croatia
Frontiers in Psychology
Hospital Anxiety and Depression Scale (HADS)
psychometrics
depression
multiple sclerosis
anxiety
title Psychometric Properties of the HADS Measure of Anxiety and Depression Among Multiple Sclerosis Patients in Croatia
title_full Psychometric Properties of the HADS Measure of Anxiety and Depression Among Multiple Sclerosis Patients in Croatia
title_fullStr Psychometric Properties of the HADS Measure of Anxiety and Depression Among Multiple Sclerosis Patients in Croatia
title_full_unstemmed Psychometric Properties of the HADS Measure of Anxiety and Depression Among Multiple Sclerosis Patients in Croatia
title_short Psychometric Properties of the HADS Measure of Anxiety and Depression Among Multiple Sclerosis Patients in Croatia
title_sort psychometric properties of the hads measure of anxiety and depression among multiple sclerosis patients in croatia
topic Hospital Anxiety and Depression Scale (HADS)
psychometrics
depression
multiple sclerosis
anxiety
url https://www.frontiersin.org/articles/10.3389/fpsyg.2021.794353/full
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