A study of morbidity and mortality pattern of pre-term neonates in neonatal intensive care unit of a tertiary care hospital of North East India
Background: Pre-maturity is one of the major health problems and associated with high morbidities and mortality. According to the WHO every year, an estimated 15 million babies are born pre-term and this number is rising. Aims and Objectives: The objectives of the study were to know the various m...
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| Format: | Article |
| Language: | English |
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Manipal College of Medical Sciences, Pokhara
2023-12-01
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| Series: | Asian Journal of Medical Sciences |
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| Online Access: | https://www.nepjol.info/index.php/AJMS/article/view/57113 |
| _version_ | 1827617629787914240 |
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| author | Dulal Kalita Mahibur Rahman Diganta Barman |
| author_facet | Dulal Kalita Mahibur Rahman Diganta Barman |
| author_sort | Dulal Kalita |
| collection | DOAJ |
| description | Background: Pre-maturity is one of the major health problems and associated with high morbidities and mortality. According to the WHO every year, an estimated 15 million babies are born pre-term and this number is rising.
Aims and Objectives: The objectives of the study were to know the various morbidity pattern developed during the clinical course and to identify the cause of mortality of pre-term babies admitted in neonatal intensive care unit (NICU).
Materials and Methods: This prospective, observational study was conducted in the Neonatal Intensive Care Unit of Gauhati Medical College and Hospital, Assam, over a period of 1 year. A sample size of 150 pre-term babies selected randomly as per inclusion and exclusion criteria.
Results: The total number of cases studied in the present study were 150 pre-term babies admitted in NICU. Male pre-term babies were 82 (54.6%) and female pre-term babies were 68 (45.3%). The various morbidities observed among the pre-term babies during the study period were neonatal hyperbilirubinemia (48%) followed by respiratory distress syndrome (RDS) (30%), neonatal sepsis (22%), hypocalcemia (16%), hypothermia (14.7%), necrotizing enterocolitis (NEC) (5.3%), and intraventricular hemorrhage (4.7%). The overall mortality among the studied cases was 12.6%. Out of 150 cases, 19 cases were expired (12.6%). The present study shows that RDS (36.8%), neonatal sepsis (26.3%), birth asphyxia (21.1%), and NEC (15.7%) were the major causes of mortality among pre-term babies.
Conclusion: The survival rate increases significantly with increase in birth weight and gestational age. RDS, birth asphyxia, and neonatal sepsis were the leading causes of death. |
| first_indexed | 2024-03-09T09:50:46Z |
| format | Article |
| id | doaj.art-3a53a8dfd60544edbbb5dc260c41e7b2 |
| institution | Directory Open Access Journal |
| issn | 2467-9100 2091-0576 |
| language | English |
| last_indexed | 2024-03-09T09:50:46Z |
| publishDate | 2023-12-01 |
| publisher | Manipal College of Medical Sciences, Pokhara |
| record_format | Article |
| series | Asian Journal of Medical Sciences |
| spelling | doaj.art-3a53a8dfd60544edbbb5dc260c41e7b22023-12-02T00:07:16ZengManipal College of Medical Sciences, PokharaAsian Journal of Medical Sciences2467-91002091-05762023-12-011412205210https://doi.org/10.3126/ajms.v14i12.57113A study of morbidity and mortality pattern of pre-term neonates in neonatal intensive care unit of a tertiary care hospital of North East IndiaDulal Kalita 0https://orcid.org/0009-0003-0465-276XMahibur Rahman1https://orcid.org/0000-0003-4002-7972Diganta Barman 2https://orcid.org/0009-0007-1460-0866Associate Professor, Department of Pediatrics, Gauhati Medical College and Hospital, Guwahati, Assam, India Assistant Professor, Department of Pediatrics, Gauhati Medical College and Hospital, Guwahati, Assam, India Assistant Professor, Department of Pediatrics, Gauhati Medical College and Hospital, Guwahati, Assam, India Background: Pre-maturity is one of the major health problems and associated with high morbidities and mortality. According to the WHO every year, an estimated 15 million babies are born pre-term and this number is rising. Aims and Objectives: The objectives of the study were to know the various morbidity pattern developed during the clinical course and to identify the cause of mortality of pre-term babies admitted in neonatal intensive care unit (NICU). Materials and Methods: This prospective, observational study was conducted in the Neonatal Intensive Care Unit of Gauhati Medical College and Hospital, Assam, over a period of 1 year. A sample size of 150 pre-term babies selected randomly as per inclusion and exclusion criteria. Results: The total number of cases studied in the present study were 150 pre-term babies admitted in NICU. Male pre-term babies were 82 (54.6%) and female pre-term babies were 68 (45.3%). The various morbidities observed among the pre-term babies during the study period were neonatal hyperbilirubinemia (48%) followed by respiratory distress syndrome (RDS) (30%), neonatal sepsis (22%), hypocalcemia (16%), hypothermia (14.7%), necrotizing enterocolitis (NEC) (5.3%), and intraventricular hemorrhage (4.7%). The overall mortality among the studied cases was 12.6%. Out of 150 cases, 19 cases were expired (12.6%). The present study shows that RDS (36.8%), neonatal sepsis (26.3%), birth asphyxia (21.1%), and NEC (15.7%) were the major causes of mortality among pre-term babies. Conclusion: The survival rate increases significantly with increase in birth weight and gestational age. RDS, birth asphyxia, and neonatal sepsis were the leading causes of death.https://www.nepjol.info/index.php/AJMS/article/view/57113pre-term babies; low birth weight; respiratory distress syndrome; sepsis; morbidity; mortality |
| spellingShingle | Dulal Kalita Mahibur Rahman Diganta Barman A study of morbidity and mortality pattern of pre-term neonates in neonatal intensive care unit of a tertiary care hospital of North East India Asian Journal of Medical Sciences pre-term babies; low birth weight; respiratory distress syndrome; sepsis; morbidity; mortality |
| title | A study of morbidity and mortality pattern of pre-term neonates in neonatal intensive care unit of a tertiary care hospital of North East India |
| title_full | A study of morbidity and mortality pattern of pre-term neonates in neonatal intensive care unit of a tertiary care hospital of North East India |
| title_fullStr | A study of morbidity and mortality pattern of pre-term neonates in neonatal intensive care unit of a tertiary care hospital of North East India |
| title_full_unstemmed | A study of morbidity and mortality pattern of pre-term neonates in neonatal intensive care unit of a tertiary care hospital of North East India |
| title_short | A study of morbidity and mortality pattern of pre-term neonates in neonatal intensive care unit of a tertiary care hospital of North East India |
| title_sort | study of morbidity and mortality pattern of pre term neonates in neonatal intensive care unit of a tertiary care hospital of north east india |
| topic | pre-term babies; low birth weight; respiratory distress syndrome; sepsis; morbidity; mortality |
| url | https://www.nepjol.info/index.php/AJMS/article/view/57113 |
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