An Interesting Similarity of Bacillus Calmette-Guerin and Chimeric Antigen Receptor T Cells
Intravesical Bacillus Calmette-Guerin (BCG) is approved for non-muscle invasive bladder cancer treatment a long time ago. Chimeric antigen receptor T cells (CAR-Tcell), are T cells are genetically engineered T cells that produce an artificial T-cell receptor for use in immunotherapy. Chimeric antige...
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| Format: | Article |
| Language: | English |
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Urology Research Center
2020-08-01
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| Series: | Translational Research in Urology |
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| Online Access: | https://www.transresurology.com/article_124781.html |
| _version_ | 1819200091276181504 |
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| author | Seyed Saeed Tamehri Zadeh AhmadReza Rezaeian |
| author_facet | Seyed Saeed Tamehri Zadeh AhmadReza Rezaeian |
| author_sort | Seyed Saeed Tamehri Zadeh |
| collection | DOAJ |
| description | Intravesical Bacillus Calmette-Guerin (BCG) is approved for non-muscle invasive bladder cancer treatment a long time ago. Chimeric antigen receptor T cells (CAR-Tcell), are T cells are genetically engineered T cells that produce an artificial T-cell receptor for use in immunotherapy. Chimeric antigen receptors are receptor proteins that have been engineered to give T cells the new ability to target a specific protein Its effect is mostly achieved using activating the immune system; the same mechanism proposed likely for chimeric antigen receptor (CAR) T cells. Hence CAR-T cell therapy could be considered for bladder cancer treatment. |
| first_indexed | 2024-12-23T03:26:43Z |
| format | Article |
| id | doaj.art-3a53ef52572b4e01b9c5a4e99fb990af |
| institution | Directory Open Access Journal |
| issn | 2717-042X |
| language | English |
| last_indexed | 2024-12-23T03:26:43Z |
| publishDate | 2020-08-01 |
| publisher | Urology Research Center |
| record_format | Article |
| series | Translational Research in Urology |
| spelling | doaj.art-3a53ef52572b4e01b9c5a4e99fb990af2022-12-21T18:01:50ZengUrology Research CenterTranslational Research in Urology2717-042X2020-08-012310710910.22034/TRU.2021.266267.1057An Interesting Similarity of Bacillus Calmette-Guerin and Chimeric Antigen Receptor T CellsSeyed Saeed Tamehri Zadeh0AhmadReza Rezaeian1Urology Research Center, Tehran University of Medical Sciences, Tehran, IranFaculty of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, IranIntravesical Bacillus Calmette-Guerin (BCG) is approved for non-muscle invasive bladder cancer treatment a long time ago. Chimeric antigen receptor T cells (CAR-Tcell), are T cells are genetically engineered T cells that produce an artificial T-cell receptor for use in immunotherapy. Chimeric antigen receptors are receptor proteins that have been engineered to give T cells the new ability to target a specific protein Its effect is mostly achieved using activating the immune system; the same mechanism proposed likely for chimeric antigen receptor (CAR) T cells. Hence CAR-T cell therapy could be considered for bladder cancer treatment.https://www.transresurology.com/article_124781.htmlcar-t cellbacillus calmette-guerinbladder cancer treatment |
| spellingShingle | Seyed Saeed Tamehri Zadeh AhmadReza Rezaeian An Interesting Similarity of Bacillus Calmette-Guerin and Chimeric Antigen Receptor T Cells Translational Research in Urology car-t cell bacillus calmette-guerin bladder cancer treatment |
| title | An Interesting Similarity of Bacillus Calmette-Guerin and Chimeric Antigen Receptor T Cells |
| title_full | An Interesting Similarity of Bacillus Calmette-Guerin and Chimeric Antigen Receptor T Cells |
| title_fullStr | An Interesting Similarity of Bacillus Calmette-Guerin and Chimeric Antigen Receptor T Cells |
| title_full_unstemmed | An Interesting Similarity of Bacillus Calmette-Guerin and Chimeric Antigen Receptor T Cells |
| title_short | An Interesting Similarity of Bacillus Calmette-Guerin and Chimeric Antigen Receptor T Cells |
| title_sort | interesting similarity of bacillus calmette guerin and chimeric antigen receptor t cells |
| topic | car-t cell bacillus calmette-guerin bladder cancer treatment |
| url | https://www.transresurology.com/article_124781.html |
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