Intraoperative fluorescence diagnosis for removal of cervical and thoracic ependymoma

The case of successful intraoperative fluorescence diagnosis (IOFD) for removal of cervical and thoracic ependymoma performed in P.A. Herzen MCRI is reported. For FD we used the Alasens (Research Institute of Organic Semi-Finished Products and Dyes). The drug solution was given per os at a dose of 2...

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Main Authors: A. M. Zaytcev, M. I. Kurzhupov, Ju. V. Kushelj, E. V. Filonenko, V. I. Ivanova-Radkevich
Format: Article
Language:Russian
Published: Non-profit partnership for development of domestic photodynamic therapy and photodiagnosis "Russian Photodynamic Association" 2014-06-01
Series:Biomedical Photonics
Subjects:
Online Access:https://www.pdt-journal.com/jour/article/view/35
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author A. M. Zaytcev
M. I. Kurzhupov
Ju. V. Kushelj
E. V. Filonenko
V. I. Ivanova-Radkevich
author_facet A. M. Zaytcev
M. I. Kurzhupov
Ju. V. Kushelj
E. V. Filonenko
V. I. Ivanova-Radkevich
author_sort A. M. Zaytcev
collection DOAJ
description The case of successful intraoperative fluorescence diagnosis (IOFD) for removal of cervical and thoracic ependymoma performed in P.A. Herzen MCRI is reported. For FD we used the Alasens (Research Institute of Organic Semi-Finished Products and Dyes). The drug solution was given per os at a dose of 20 mg/kg body weight 2.5 h before surgery. IOFD was per-formed 3 h after intake of photosensitizer. For fluorescence diagnosis there was average in-tensity of fluorescence in tumor and no fluorescence in normal spinal tissues. The extent of surgery was determined according to results of IOFD. The control MRI of cervical and supeior thoracic spine with contrast enhancement and follow-up confirmed definitive removal of tumor and showed no postoperative complications.
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spelling doaj.art-3a58b3c9e4154313953384d60386c1812025-03-02T12:41:32ZrusNon-profit partnership for development of domestic photodynamic therapy and photodiagnosis "Russian Photodynamic Association"Biomedical Photonics2413-94322014-06-0132242735Intraoperative fluorescence diagnosis for removal of cervical and thoracic ependymomaA. M. Zaytcev0M. I. Kurzhupov1Ju. V. Kushelj2E. V. Filonenko3V. I. Ivanova-Radkevich4P.A.Herzen Moscow Cancer Research Institute, MoscowP.A.Herzen Moscow Cancer Research Institute, MoscowN.N. Burdenko Research Institute of Neurosurgery, MoscowP.A.Herzen Moscow Cancer Research Institute, MoscowPeoples Friendship University of Russia, MoscowThe case of successful intraoperative fluorescence diagnosis (IOFD) for removal of cervical and thoracic ependymoma performed in P.A. Herzen MCRI is reported. For FD we used the Alasens (Research Institute of Organic Semi-Finished Products and Dyes). The drug solution was given per os at a dose of 20 mg/kg body weight 2.5 h before surgery. IOFD was per-formed 3 h after intake of photosensitizer. For fluorescence diagnosis there was average in-tensity of fluorescence in tumor and no fluorescence in normal spinal tissues. The extent of surgery was determined according to results of IOFD. The control MRI of cervical and supeior thoracic spine with contrast enhancement and follow-up confirmed definitive removal of tumor and showed no postoperative complications.https://www.pdt-journal.com/jour/article/view/35ependymomaalasensintraoperative fluorescence diagnosis
spellingShingle A. M. Zaytcev
M. I. Kurzhupov
Ju. V. Kushelj
E. V. Filonenko
V. I. Ivanova-Radkevich
Intraoperative fluorescence diagnosis for removal of cervical and thoracic ependymoma
Biomedical Photonics
ependymoma
alasens
intraoperative fluorescence diagnosis
title Intraoperative fluorescence diagnosis for removal of cervical and thoracic ependymoma
title_full Intraoperative fluorescence diagnosis for removal of cervical and thoracic ependymoma
title_fullStr Intraoperative fluorescence diagnosis for removal of cervical and thoracic ependymoma
title_full_unstemmed Intraoperative fluorescence diagnosis for removal of cervical and thoracic ependymoma
title_short Intraoperative fluorescence diagnosis for removal of cervical and thoracic ependymoma
title_sort intraoperative fluorescence diagnosis for removal of cervical and thoracic ependymoma
topic ependymoma
alasens
intraoperative fluorescence diagnosis
url https://www.pdt-journal.com/jour/article/view/35
work_keys_str_mv AT amzaytcev intraoperativefluorescencediagnosisforremovalofcervicalandthoracicependymoma
AT mikurzhupov intraoperativefluorescencediagnosisforremovalofcervicalandthoracicependymoma
AT juvkushelj intraoperativefluorescencediagnosisforremovalofcervicalandthoracicependymoma
AT evfilonenko intraoperativefluorescencediagnosisforremovalofcervicalandthoracicependymoma
AT viivanovaradkevich intraoperativefluorescencediagnosisforremovalofcervicalandthoracicependymoma