PROTEINS OF THE ERYTHROCYTE MEMBRANE AND METABOLIC SYNDROME

There is no literature data on the changes of structural and functional qualities of the erythrocyte membrane at the arterial hypertension (AH) complicated and non-complicated by the metabolic syndrome (MS). Although the changes of interrelation between the proteins of erythrocyte membrane at the AH...

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Main Authors: A. S. Sergeyeva, Y. I. Pivovarov, I. V. Babushkina, L. B. Koryakina, E. O. Andreeva
Format: Article
Language:Russian
Published: Scientific Сentre for Family Health and Human Reproduction Problems 2015-07-01
Series:Acta Biomedica Scientifica
Subjects:
Online Access:https://www.actabiomedica.ru/jour/article/view/83
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author A. S. Sergeyeva
Y. I. Pivovarov
I. V. Babushkina
L. B. Koryakina
E. O. Andreeva
author_facet A. S. Sergeyeva
Y. I. Pivovarov
I. V. Babushkina
L. B. Koryakina
E. O. Andreeva
author_sort A. S. Sergeyeva
collection DOAJ
description There is no literature data on the changes of structural and functional qualities of the erythrocyte membrane at the arterial hypertension (AH) complicated and non-complicated by the metabolic syndrome (MS). Although the changes of interrelation between the proteins of erythrocyte membrane at the AH can influence the deformability of the membrane itself. The aim of the work was to estimate the peculiarities of interrelation between the proteins of erythrocyte membrane in the patients with arterial hypertension complicated and non-complicated by the metabolic syndrome. The research included 51 men with AH and 29 clinically healthy men which were divided into 3 groups: group 1 - control; group 2 - men with AH complicated with MS (n = 29); group 3 - men with AH non-complicated with MS (n = 22). We studied blood lipids, biochemical and hemostasiological parameters, assessed 10 proteins of erythrocyte membrane. Patients of the 2nd and 3rd groups had different content of α- and β-spectrins, anion-transport protein (ATP), plates 4.1, glycerol-3-phosphatededehydrogenase (G-3-PDG), glutathione S-transferase (GST). The results of the research showed that metabolic syndrome at the AH can not only influence the state of vessel wall but also cause significant disorders of structural and functional qualities of the erythrocyte membrane.
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spelling doaj.art-3a5ecfdabfa941aa9618c30a815b1f7d2024-03-28T07:49:14ZrusScientific Сentre for Family Health and Human Reproduction ProblemsActa Biomedica Scientifica2541-94202587-95962015-07-0104121783PROTEINS OF THE ERYTHROCYTE MEMBRANE AND METABOLIC SYNDROMEA. S. Sergeyeva0Y. I. Pivovarov1I. V. Babushkina2L. B. Koryakina3E. O. Andreeva4Irkutsk Scientific Center of Surgery and TraumatologyIrkutsk Scientific Center of Surgery and TraumatologyIrkutsk Scientific Center of Surgery and TraumatologyIrkutsk Scientific Center of Surgery and TraumatologyIrkutsk Scientific Center of Surgery and TraumatologyThere is no literature data on the changes of structural and functional qualities of the erythrocyte membrane at the arterial hypertension (AH) complicated and non-complicated by the metabolic syndrome (MS). Although the changes of interrelation between the proteins of erythrocyte membrane at the AH can influence the deformability of the membrane itself. The aim of the work was to estimate the peculiarities of interrelation between the proteins of erythrocyte membrane in the patients with arterial hypertension complicated and non-complicated by the metabolic syndrome. The research included 51 men with AH and 29 clinically healthy men which were divided into 3 groups: group 1 - control; group 2 - men with AH complicated with MS (n = 29); group 3 - men with AH non-complicated with MS (n = 22). We studied blood lipids, biochemical and hemostasiological parameters, assessed 10 proteins of erythrocyte membrane. Patients of the 2nd and 3rd groups had different content of α- and β-spectrins, anion-transport protein (ATP), plates 4.1, glycerol-3-phosphatededehydrogenase (G-3-PDG), glutathione S-transferase (GST). The results of the research showed that metabolic syndrome at the AH can not only influence the state of vessel wall but also cause significant disorders of structural and functional qualities of the erythrocyte membrane.https://www.actabiomedica.ru/jour/article/view/83arterial hypertensionmetabolic syndromeerythrocyte membraneproteins
spellingShingle A. S. Sergeyeva
Y. I. Pivovarov
I. V. Babushkina
L. B. Koryakina
E. O. Andreeva
PROTEINS OF THE ERYTHROCYTE MEMBRANE AND METABOLIC SYNDROME
Acta Biomedica Scientifica
arterial hypertension
metabolic syndrome
erythrocyte membrane
proteins
title PROTEINS OF THE ERYTHROCYTE MEMBRANE AND METABOLIC SYNDROME
title_full PROTEINS OF THE ERYTHROCYTE MEMBRANE AND METABOLIC SYNDROME
title_fullStr PROTEINS OF THE ERYTHROCYTE MEMBRANE AND METABOLIC SYNDROME
title_full_unstemmed PROTEINS OF THE ERYTHROCYTE MEMBRANE AND METABOLIC SYNDROME
title_short PROTEINS OF THE ERYTHROCYTE MEMBRANE AND METABOLIC SYNDROME
title_sort proteins of the erythrocyte membrane and metabolic syndrome
topic arterial hypertension
metabolic syndrome
erythrocyte membrane
proteins
url https://www.actabiomedica.ru/jour/article/view/83
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AT yipivovarov proteinsoftheerythrocytemembraneandmetabolicsyndrome
AT ivbabushkina proteinsoftheerythrocytemembraneandmetabolicsyndrome
AT lbkoryakina proteinsoftheerythrocytemembraneandmetabolicsyndrome
AT eoandreeva proteinsoftheerythrocytemembraneandmetabolicsyndrome