Cell Membrane Coating Technology: A Promising Strategy for Biomedical Applications
Abstract Cell membrane coating technology is an approach to the biomimetic replication of cell membrane properties, and is an active area of ongoing research readily applicable to nanoscale biomedicine. Nanoparticles (NPs) coated with cell membranes offer an opportunity to unite natural cell membran...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
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SpringerOpen
2019-11-01
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Series: | Nano-Micro Letters |
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Online Access: | http://link.springer.com/article/10.1007/s40820-019-0330-9 |
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author | Yao Liu Jingshan Luo Xiaojia Chen Wei Liu Tongkai Chen |
author_facet | Yao Liu Jingshan Luo Xiaojia Chen Wei Liu Tongkai Chen |
author_sort | Yao Liu |
collection | DOAJ |
description | Abstract Cell membrane coating technology is an approach to the biomimetic replication of cell membrane properties, and is an active area of ongoing research readily applicable to nanoscale biomedicine. Nanoparticles (NPs) coated with cell membranes offer an opportunity to unite natural cell membrane properties with those of the artificial inner core material. The coated NPs not only increase their biocompatibility but also achieve effective and extended circulation in vivo, allowing for the execution of targeted functions. Although cell membrane-coated NPs offer clear advantages, much work remains before they can be applied in clinical practice. In this review, we first provide a comprehensive overview of the theory of cell membrane coating technology, followed by a summary of the existing preparation and characterization techniques. Next, we focus on the functions and applications of various cell membrane types. In addition, we collate model drugs used in cell membrane coating technology, and review the patent applications related to this technology from the past 10 years. Finally, we survey future challenges and trends pertaining to this technology in an effort to provide a comprehensive overview of the future development of cell membrane coating technology. |
first_indexed | 2024-12-12T10:04:06Z |
format | Article |
id | doaj.art-3a5f5df7d9cf495bbb711e4a033f9f40 |
institution | Directory Open Access Journal |
issn | 2311-6706 2150-5551 |
language | English |
last_indexed | 2024-12-12T10:04:06Z |
publishDate | 2019-11-01 |
publisher | SpringerOpen |
record_format | Article |
series | Nano-Micro Letters |
spelling | doaj.art-3a5f5df7d9cf495bbb711e4a033f9f402022-12-22T00:27:56ZengSpringerOpenNano-Micro Letters2311-67062150-55512019-11-0111114610.1007/s40820-019-0330-9Cell Membrane Coating Technology: A Promising Strategy for Biomedical ApplicationsYao Liu0Jingshan Luo1Xiaojia Chen2Wei Liu3Tongkai Chen4Science and Technology Innovation Center, Guangzhou University of Chinese MedicineScience and Technology Innovation Center, Guangzhou University of Chinese MedicineState Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of MacauKey Laboratory of Artificial Micro- and Nano-Structures of Ministry of Education, School of Physics and Technology, Wuhan UniversityScience and Technology Innovation Center, Guangzhou University of Chinese MedicineAbstract Cell membrane coating technology is an approach to the biomimetic replication of cell membrane properties, and is an active area of ongoing research readily applicable to nanoscale biomedicine. Nanoparticles (NPs) coated with cell membranes offer an opportunity to unite natural cell membrane properties with those of the artificial inner core material. The coated NPs not only increase their biocompatibility but also achieve effective and extended circulation in vivo, allowing for the execution of targeted functions. Although cell membrane-coated NPs offer clear advantages, much work remains before they can be applied in clinical practice. In this review, we first provide a comprehensive overview of the theory of cell membrane coating technology, followed by a summary of the existing preparation and characterization techniques. Next, we focus on the functions and applications of various cell membrane types. In addition, we collate model drugs used in cell membrane coating technology, and review the patent applications related to this technology from the past 10 years. Finally, we survey future challenges and trends pertaining to this technology in an effort to provide a comprehensive overview of the future development of cell membrane coating technology.http://link.springer.com/article/10.1007/s40820-019-0330-9Cell membraneBiomimetic nanoparticlesCancer therapyImmune modulationDetoxification |
spellingShingle | Yao Liu Jingshan Luo Xiaojia Chen Wei Liu Tongkai Chen Cell Membrane Coating Technology: A Promising Strategy for Biomedical Applications Nano-Micro Letters Cell membrane Biomimetic nanoparticles Cancer therapy Immune modulation Detoxification |
title | Cell Membrane Coating Technology: A Promising Strategy for Biomedical Applications |
title_full | Cell Membrane Coating Technology: A Promising Strategy for Biomedical Applications |
title_fullStr | Cell Membrane Coating Technology: A Promising Strategy for Biomedical Applications |
title_full_unstemmed | Cell Membrane Coating Technology: A Promising Strategy for Biomedical Applications |
title_short | Cell Membrane Coating Technology: A Promising Strategy for Biomedical Applications |
title_sort | cell membrane coating technology a promising strategy for biomedical applications |
topic | Cell membrane Biomimetic nanoparticles Cancer therapy Immune modulation Detoxification |
url | http://link.springer.com/article/10.1007/s40820-019-0330-9 |
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