Maternal and fetal outcomes in pregnant females with rheumatic heart disease
Background: Cardiac diseases are seen in 1–3% of pregnancies. In developing countries rheumatic heart disease (RHD) contributes a major cause of cardiac disorders. Objective: To study the maternal and fetal outcome in women with valvular heart disease or prosthetic heart valve replacement secondary...
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| Format: | Article |
| Language: | English |
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Elsevier
2021-03-01
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| Series: | Indian Heart Journal |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S0019483221000122 |
| _version_ | 1819283525662146560 |
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| author | Roopali Khanna Deepti Chandra Sangeeta Yadav Ankit Sahu Neeta Singh Sudeep Kumar Naveen Garg Satyendra Tewari Aditya Kapoor Mandakini Pradhan Pravin K. Goel |
| author_facet | Roopali Khanna Deepti Chandra Sangeeta Yadav Ankit Sahu Neeta Singh Sudeep Kumar Naveen Garg Satyendra Tewari Aditya Kapoor Mandakini Pradhan Pravin K. Goel |
| author_sort | Roopali Khanna |
| collection | DOAJ |
| description | Background: Cardiac diseases are seen in 1–3% of pregnancies. In developing countries rheumatic heart disease (RHD) contributes a major cause of cardiac disorders. Objective: To study the maternal and fetal outcome in women with valvular heart disease or prosthetic heart valve replacement secondary to RHD in a tertiary care center. Method: The consecutive pregnant women with RHD attending our institute from May 2018 to August 2019 were included. A maternal adverse outcome was defined as cardiac death, new onset arrhythmia, heart failure, thromboembolic event, hospitalization for other cardiac reasons or cardiac intervention, aortic dissection, infective endocarditis and acute coronary syndrome. Fetal adverse outcome defined as fetal death, preterm birth, and low birth weight. Result: Total 80 patients were included in this study, native RHD in 60(75%) and 20(25%) had mechanical prosthetic valve replacement. Maternal adverse event occurred in 34(42.5%), comprising of death in 1(1.2%), new onset AF 2(2.5%), 20(25%) underwent balloon mitral valvotomy, 3(3.7%) underwent mitral valve replacement, heart failure hospitalization in 7(8.7%). 1(1.2%) patient developed mitral valve infective endocarditis. Preterm delivery occurred in 19(23.7%), 7(8.7%) abortions and 1(1.2%) intrauterine death. Fetuses with low birth weight were 43(53.7%). Pregnancy with live birth occurred in 57(95%) women with valvular heart disease but no prosthesis and 16(80%) women with prosthetic valve disease. Conclusion: Women with rheumatic heart disease carry a high risk both for mother and fetus. Early diagnosis, close follow-up during pregnancy, early recognition of deterioration in symptoms and timely cardiac intervention can lead to good maternal or fetal outcome. |
| first_indexed | 2024-12-24T01:32:52Z |
| format | Article |
| id | doaj.art-3a5fbb8ae9064009b6ba14686077b5c3 |
| institution | Directory Open Access Journal |
| issn | 0019-4832 |
| language | English |
| last_indexed | 2024-12-24T01:32:52Z |
| publishDate | 2021-03-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Indian Heart Journal |
| spelling | doaj.art-3a5fbb8ae9064009b6ba14686077b5c32022-12-21T17:22:17ZengElsevierIndian Heart Journal0019-48322021-03-01732185189Maternal and fetal outcomes in pregnant females with rheumatic heart diseaseRoopali Khanna0Deepti Chandra1Sangeeta Yadav2Ankit Sahu3Neeta Singh4Sudeep Kumar5Naveen Garg6Satyendra Tewari7Aditya Kapoor8Mandakini Pradhan9Pravin K. Goel10Department of Cardiology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India; Corresponding author. Department of Cardiology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Raebareli Road, Lucknow, 226014, India.Department of Cardiology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, IndiaDepartment of Cardiology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, IndiaDepartment of Cardiology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, IndiaDepartment of Maternal and Reproductive Health, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, IndiaDepartment of Cardiology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, IndiaDepartment of Cardiology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, IndiaDepartment of Cardiology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, IndiaDepartment of Cardiology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, IndiaDepartment of Maternal and Reproductive Health, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, IndiaDepartment of Cardiology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, IndiaBackground: Cardiac diseases are seen in 1–3% of pregnancies. In developing countries rheumatic heart disease (RHD) contributes a major cause of cardiac disorders. Objective: To study the maternal and fetal outcome in women with valvular heart disease or prosthetic heart valve replacement secondary to RHD in a tertiary care center. Method: The consecutive pregnant women with RHD attending our institute from May 2018 to August 2019 were included. A maternal adverse outcome was defined as cardiac death, new onset arrhythmia, heart failure, thromboembolic event, hospitalization for other cardiac reasons or cardiac intervention, aortic dissection, infective endocarditis and acute coronary syndrome. Fetal adverse outcome defined as fetal death, preterm birth, and low birth weight. Result: Total 80 patients were included in this study, native RHD in 60(75%) and 20(25%) had mechanical prosthetic valve replacement. Maternal adverse event occurred in 34(42.5%), comprising of death in 1(1.2%), new onset AF 2(2.5%), 20(25%) underwent balloon mitral valvotomy, 3(3.7%) underwent mitral valve replacement, heart failure hospitalization in 7(8.7%). 1(1.2%) patient developed mitral valve infective endocarditis. Preterm delivery occurred in 19(23.7%), 7(8.7%) abortions and 1(1.2%) intrauterine death. Fetuses with low birth weight were 43(53.7%). Pregnancy with live birth occurred in 57(95%) women with valvular heart disease but no prosthesis and 16(80%) women with prosthetic valve disease. Conclusion: Women with rheumatic heart disease carry a high risk both for mother and fetus. Early diagnosis, close follow-up during pregnancy, early recognition of deterioration in symptoms and timely cardiac intervention can lead to good maternal or fetal outcome.http://www.sciencedirect.com/science/article/pii/S0019483221000122Rheumatic heart diseasePregnancyBalloon mitral valvotomy |
| spellingShingle | Roopali Khanna Deepti Chandra Sangeeta Yadav Ankit Sahu Neeta Singh Sudeep Kumar Naveen Garg Satyendra Tewari Aditya Kapoor Mandakini Pradhan Pravin K. Goel Maternal and fetal outcomes in pregnant females with rheumatic heart disease Indian Heart Journal Rheumatic heart disease Pregnancy Balloon mitral valvotomy |
| title | Maternal and fetal outcomes in pregnant females with rheumatic heart disease |
| title_full | Maternal and fetal outcomes in pregnant females with rheumatic heart disease |
| title_fullStr | Maternal and fetal outcomes in pregnant females with rheumatic heart disease |
| title_full_unstemmed | Maternal and fetal outcomes in pregnant females with rheumatic heart disease |
| title_short | Maternal and fetal outcomes in pregnant females with rheumatic heart disease |
| title_sort | maternal and fetal outcomes in pregnant females with rheumatic heart disease |
| topic | Rheumatic heart disease Pregnancy Balloon mitral valvotomy |
| url | http://www.sciencedirect.com/science/article/pii/S0019483221000122 |
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