Carbon nanotubes as a novel drug delivery system for anticancer therapy: a review
Carbon nanotubes (CNTs) were discovered in 1991 and shown to have certain unique physicochemical properties, attracting considerable interest in their application in various fields including drug delivery. The unique properties of CNTs such as ease of cellular uptake, high drug loading, thermal abla...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Universidade de São Paulo
2013-12-01
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| Series: | Brazilian Journal of Pharmaceutical Sciences |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502013000400002&lng=en&tlng=en |
| _version_ | 1819047997041803264 |
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| author | Swatantra Kumar Singh Kushwaha Saurav Ghoshal Awani Kumar Rai Satyawan Singh |
| author_facet | Swatantra Kumar Singh Kushwaha Saurav Ghoshal Awani Kumar Rai Satyawan Singh |
| author_sort | Swatantra Kumar Singh Kushwaha |
| collection | DOAJ |
| description | Carbon nanotubes (CNTs) were discovered in 1991 and shown to have certain unique physicochemical properties, attracting considerable interest in their application in various fields including drug delivery. The unique properties of CNTs such as ease of cellular uptake, high drug loading, thermal ablation, among others, render them useful for cancer therapy. Cancer is one of the most challenging diseases of modern times because its therapy involves distinguishing normal healthy cells from affected cells. Here, CNTs play a major role because phenomena such as EPR, allow CNTs to distinguish normal cells from affected ones, the Holy Grail in cancer therapy. Considerable work has been done on CNTs as drug delivery systems over the last two decades. However, concerns over certain issues such as biocompatibility and toxicity have been raised and warrant extensive research in this field. |
| first_indexed | 2024-12-21T11:09:15Z |
| format | Article |
| id | doaj.art-3a653a43e5174a71a64ec620dde05c7a |
| institution | Directory Open Access Journal |
| issn | 2175-9790 |
| language | English |
| last_indexed | 2024-12-21T11:09:15Z |
| publishDate | 2013-12-01 |
| publisher | Universidade de São Paulo |
| record_format | Article |
| series | Brazilian Journal of Pharmaceutical Sciences |
| spelling | doaj.art-3a653a43e5174a71a64ec620dde05c7a2022-12-21T19:06:08ZengUniversidade de São PauloBrazilian Journal of Pharmaceutical Sciences2175-97902013-12-0149462964310.1590/S1984-82502013000400002S1984-82502013000400002Carbon nanotubes as a novel drug delivery system for anticancer therapy: a reviewSwatantra Kumar Singh Kushwaha0Saurav Ghoshal1Awani Kumar Rai2Satyawan Singh3Pranveer Singh Institute of TechnologyPranveer Singh Institute of TechnologyPranveer Singh Institute of TechnologySaroj Institute of Technology & ManagementCarbon nanotubes (CNTs) were discovered in 1991 and shown to have certain unique physicochemical properties, attracting considerable interest in their application in various fields including drug delivery. The unique properties of CNTs such as ease of cellular uptake, high drug loading, thermal ablation, among others, render them useful for cancer therapy. Cancer is one of the most challenging diseases of modern times because its therapy involves distinguishing normal healthy cells from affected cells. Here, CNTs play a major role because phenomena such as EPR, allow CNTs to distinguish normal cells from affected ones, the Holy Grail in cancer therapy. Considerable work has been done on CNTs as drug delivery systems over the last two decades. However, concerns over certain issues such as biocompatibility and toxicity have been raised and warrant extensive research in this field.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502013000400002&lng=en&tlng=enNanotubos de carbonoNanotubos de carbonoNanotubos de carbonoNanotubo de carbono de parede únicaNanotubo de parede múltiplaFármacos anticancerCancerFármacos |
| spellingShingle | Swatantra Kumar Singh Kushwaha Saurav Ghoshal Awani Kumar Rai Satyawan Singh Carbon nanotubes as a novel drug delivery system for anticancer therapy: a review Brazilian Journal of Pharmaceutical Sciences Nanotubos de carbono Nanotubos de carbono Nanotubos de carbono Nanotubo de carbono de parede única Nanotubo de parede múltipla Fármacos anticancer Cancer Fármacos |
| title | Carbon nanotubes as a novel drug delivery system for anticancer therapy: a review |
| title_full | Carbon nanotubes as a novel drug delivery system for anticancer therapy: a review |
| title_fullStr | Carbon nanotubes as a novel drug delivery system for anticancer therapy: a review |
| title_full_unstemmed | Carbon nanotubes as a novel drug delivery system for anticancer therapy: a review |
| title_short | Carbon nanotubes as a novel drug delivery system for anticancer therapy: a review |
| title_sort | carbon nanotubes as a novel drug delivery system for anticancer therapy a review |
| topic | Nanotubos de carbono Nanotubos de carbono Nanotubos de carbono Nanotubo de carbono de parede única Nanotubo de parede múltipla Fármacos anticancer Cancer Fármacos |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502013000400002&lng=en&tlng=en |
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