The effects of TRX suspension training on sarcopenic biomarkers and functional abilities in elderlies with sarcopenia: a controlled clinical trial
Abstract Background Sarcopenia is an age-related progressive loss of muscle mass and strength that can be modulated by resistance training. This study aimed to investigate the effects of TRX Suspension Training (TST) on serum levels of neuromuscular and growth factors and functional indices in elder...
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| Format: | Article |
| Language: | English |
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BMC
2024-02-01
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| Series: | BMC Sports Science, Medicine and Rehabilitation |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s13102-024-00849-x |
| _version_ | 1797273583182938112 |
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| author | Sohrab Rezaei Rasoul Eslami Bakhtyar Tartibian |
| author_facet | Sohrab Rezaei Rasoul Eslami Bakhtyar Tartibian |
| author_sort | Sohrab Rezaei |
| collection | DOAJ |
| description | Abstract Background Sarcopenia is an age-related progressive loss of muscle mass and strength that can be modulated by resistance training. This study aimed to investigate the effects of TRX Suspension Training (TST) on serum levels of neuromuscular and growth factors and functional indices in elderly men with sarcopenia, an age-related condition characterized by progressive muscle mass and strength loss. Methods Nineteen sarcopenic elderly men (age = 74.87 ± 4.58 years) were randomly assigned into two groups, the TST group (n = 10) and the control group (n = 9). Serum concentrations of regulatory muscle markers, anthropometric and body composition indices, and functional tests were evaluated at baseline and after 8 weeks. The training protocol consisted of eight weeks of TRX exercises, with three weekly sessions. Results After 8 weeks of training, growth factors such as Follistatin (FST) (P = 0.001), 22 kDa C-terminal agrin fragment (CAF) (P = 0.031), and growth differentiation factor 15 (GDF15) (P = 0.049) increased significantly in the training group in comparison to the control group and Myostatin (MSTN) (P = 0.002) had a significant decrease. However, there was no significant difference in ASMM/m2 (P = 0.527), SMM/m2 (P = 0.621), or Body fat mass (P = 0.433) within or between groups. In addition, the TRX Suspension Training had a significant effect on the functional tests and improved gait speed (P = 0.037), chair stand (P = 0.016), and TUG (P = 0.016) as well as Handgrip strength (P = 0.035). Conclusion Our findings highlight the efficacy of TRX Suspension Training in enhancing the serum levels of muscle growth factors and functional capacities among elderly individuals with sarcopenia. Therefore, considering the ongoing COVID-19 pandemic, this protocol can prove beneficial for this demographic group. Trial registry Iranian Registry of Clinical Trials identifier: IRCT20230727058944N1, prospectively registered 20-09-2023, https://en.irct.ir/trial/71635 |
| first_indexed | 2024-03-07T14:46:29Z |
| format | Article |
| id | doaj.art-3a6582a5cbe845c8b097319fa20206ba |
| institution | Directory Open Access Journal |
| issn | 2052-1847 |
| language | English |
| last_indexed | 2024-03-07T14:46:29Z |
| publishDate | 2024-02-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Sports Science, Medicine and Rehabilitation |
| spelling | doaj.art-3a6582a5cbe845c8b097319fa20206ba2024-03-05T19:55:19ZengBMCBMC Sports Science, Medicine and Rehabilitation2052-18472024-02-0116111310.1186/s13102-024-00849-xThe effects of TRX suspension training on sarcopenic biomarkers and functional abilities in elderlies with sarcopenia: a controlled clinical trialSohrab Rezaei0Rasoul Eslami1Bakhtyar Tartibian2Exercise Physiology Department, Faculty of Sport Science, Allameh Tabataba’i UniversityExercise Physiology Department, Faculty of Sport Science, Allameh Tabataba’i UniversityExercise Physiology Department, Faculty of Sport Science, Allameh Tabataba’i UniversityAbstract Background Sarcopenia is an age-related progressive loss of muscle mass and strength that can be modulated by resistance training. This study aimed to investigate the effects of TRX Suspension Training (TST) on serum levels of neuromuscular and growth factors and functional indices in elderly men with sarcopenia, an age-related condition characterized by progressive muscle mass and strength loss. Methods Nineteen sarcopenic elderly men (age = 74.87 ± 4.58 years) were randomly assigned into two groups, the TST group (n = 10) and the control group (n = 9). Serum concentrations of regulatory muscle markers, anthropometric and body composition indices, and functional tests were evaluated at baseline and after 8 weeks. The training protocol consisted of eight weeks of TRX exercises, with three weekly sessions. Results After 8 weeks of training, growth factors such as Follistatin (FST) (P = 0.001), 22 kDa C-terminal agrin fragment (CAF) (P = 0.031), and growth differentiation factor 15 (GDF15) (P = 0.049) increased significantly in the training group in comparison to the control group and Myostatin (MSTN) (P = 0.002) had a significant decrease. However, there was no significant difference in ASMM/m2 (P = 0.527), SMM/m2 (P = 0.621), or Body fat mass (P = 0.433) within or between groups. In addition, the TRX Suspension Training had a significant effect on the functional tests and improved gait speed (P = 0.037), chair stand (P = 0.016), and TUG (P = 0.016) as well as Handgrip strength (P = 0.035). Conclusion Our findings highlight the efficacy of TRX Suspension Training in enhancing the serum levels of muscle growth factors and functional capacities among elderly individuals with sarcopenia. Therefore, considering the ongoing COVID-19 pandemic, this protocol can prove beneficial for this demographic group. Trial registry Iranian Registry of Clinical Trials identifier: IRCT20230727058944N1, prospectively registered 20-09-2023, https://en.irct.ir/trial/71635https://doi.org/10.1186/s13102-024-00849-xSarcopeniaTRX suspension trainingNeuromuscular factorGrowth factorsFunctional abilities |
| spellingShingle | Sohrab Rezaei Rasoul Eslami Bakhtyar Tartibian The effects of TRX suspension training on sarcopenic biomarkers and functional abilities in elderlies with sarcopenia: a controlled clinical trial BMC Sports Science, Medicine and Rehabilitation Sarcopenia TRX suspension training Neuromuscular factor Growth factors Functional abilities |
| title | The effects of TRX suspension training on sarcopenic biomarkers and functional abilities in elderlies with sarcopenia: a controlled clinical trial |
| title_full | The effects of TRX suspension training on sarcopenic biomarkers and functional abilities in elderlies with sarcopenia: a controlled clinical trial |
| title_fullStr | The effects of TRX suspension training on sarcopenic biomarkers and functional abilities in elderlies with sarcopenia: a controlled clinical trial |
| title_full_unstemmed | The effects of TRX suspension training on sarcopenic biomarkers and functional abilities in elderlies with sarcopenia: a controlled clinical trial |
| title_short | The effects of TRX suspension training on sarcopenic biomarkers and functional abilities in elderlies with sarcopenia: a controlled clinical trial |
| title_sort | effects of trx suspension training on sarcopenic biomarkers and functional abilities in elderlies with sarcopenia a controlled clinical trial |
| topic | Sarcopenia TRX suspension training Neuromuscular factor Growth factors Functional abilities |
| url | https://doi.org/10.1186/s13102-024-00849-x |
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