Relationship between Serum Selenium Levels and Hypertension: Findings from the National Health and Nutrition Examination Survey, 2009–2018
Objective: This study was aimed at evaluating the association between serum selenium (Se) levels and hypertension in United States (US) adults. Methods: Data were extracted from the United States National Health and Nutrition Examination Survey (NHANES, 2009–2018). Multivariate logistic regression...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Compuscript Ltd
2024-01-01
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| Series: | Cardiovascular Innovations and Applications |
| Online Access: | https://www.scienceopen.com/hosted-document?doi=10.15212/CVIA.2023.0096 |
| _version_ | 1797343400936079360 |
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| author | Wang Lili Guo Liwei |
| author_facet | Wang Lili Guo Liwei |
| author_sort | Wang Lili |
| collection | DOAJ |
| description | Objective: This study was aimed at evaluating the association between serum selenium (Se) levels and hypertension in United States (US) adults. Methods: Data were extracted from the United States National Health and Nutrition Examination Survey (NHANES, 2009–2018). Multivariate logistic regression and subgroup analysis were conducted to examine associations between Se and hypertension. Results: Patients with hypertension had higher serum Se levels than healthy participants (P = 0.01017). After adjustment for demographic and health behaviors, serum Se levels were significantly associated with systolic blood pressure in women (OR = 0.014; 95% CI: 0.001–0.027; P = 0.04174). Serum Se levels were significantly associated with diastolic blood pressure (DBP) in both women and men. In subgroup analysis, serum Se levels were significantly associated with higher diastolic blood pressure (P for trend <0.001). Conclusion: In summary, this analysis supports a nonlinear association between serum Se levels and the prevalence of hypertension, and higher serum Se levels were associated with higher DBP. |
| first_indexed | 2024-03-08T10:47:03Z |
| format | Article |
| id | doaj.art-3a68112929d7432096ef3ef9651ada4f |
| institution | Directory Open Access Journal |
| issn | 2009-8618 2009-8782 |
| language | English |
| last_indexed | 2024-03-08T10:47:03Z |
| publishDate | 2024-01-01 |
| publisher | Compuscript Ltd |
| record_format | Article |
| series | Cardiovascular Innovations and Applications |
| spelling | doaj.art-3a68112929d7432096ef3ef9651ada4f2024-01-26T17:01:16ZengCompuscript LtdCardiovascular Innovations and Applications2009-86182009-87822024-01-019198910.15212/CVIA.2023.0096Relationship between Serum Selenium Levels and Hypertension: Findings from the National Health and Nutrition Examination Survey, 2009–2018Wang LiliGuo LiweiObjective: This study was aimed at evaluating the association between serum selenium (Se) levels and hypertension in United States (US) adults. Methods: Data were extracted from the United States National Health and Nutrition Examination Survey (NHANES, 2009–2018). Multivariate logistic regression and subgroup analysis were conducted to examine associations between Se and hypertension. Results: Patients with hypertension had higher serum Se levels than healthy participants (P = 0.01017). After adjustment for demographic and health behaviors, serum Se levels were significantly associated with systolic blood pressure in women (OR = 0.014; 95% CI: 0.001–0.027; P = 0.04174). Serum Se levels were significantly associated with diastolic blood pressure (DBP) in both women and men. In subgroup analysis, serum Se levels were significantly associated with higher diastolic blood pressure (P for trend <0.001). Conclusion: In summary, this analysis supports a nonlinear association between serum Se levels and the prevalence of hypertension, and higher serum Se levels were associated with higher DBP.https://www.scienceopen.com/hosted-document?doi=10.15212/CVIA.2023.0096 |
| spellingShingle | Wang Lili Guo Liwei Relationship between Serum Selenium Levels and Hypertension: Findings from the National Health and Nutrition Examination Survey, 2009–2018 Cardiovascular Innovations and Applications |
| title | Relationship between Serum Selenium Levels and Hypertension: Findings from the National Health and Nutrition Examination Survey, 2009–2018 |
| title_full | Relationship between Serum Selenium Levels and Hypertension: Findings from the National Health and Nutrition Examination Survey, 2009–2018 |
| title_fullStr | Relationship between Serum Selenium Levels and Hypertension: Findings from the National Health and Nutrition Examination Survey, 2009–2018 |
| title_full_unstemmed | Relationship between Serum Selenium Levels and Hypertension: Findings from the National Health and Nutrition Examination Survey, 2009–2018 |
| title_short | Relationship between Serum Selenium Levels and Hypertension: Findings from the National Health and Nutrition Examination Survey, 2009–2018 |
| title_sort | relationship between serum selenium levels and hypertension findings from the national health and nutrition examination survey 2009 2018 |
| url | https://www.scienceopen.com/hosted-document?doi=10.15212/CVIA.2023.0096 |
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