Atypical presentation of Sjogren’s syndrome with MALT lymphoma mimicking chronic venous ulcers

Abstract Chronic ulcerations of the lower extremities are quite a common condition amongst adults, most often caused by chronic venous insufficiency. Irrespective of the main underlying cause, chronic limb ulcerations are usually associated with significant symptoms, impairing daily functioning. Imp...

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Main Author: Marta Wasilewska
Format: Article
Language:English
Published: Sociedade Brasileira de Angiologia e de Cirurgia Vascular (SBACV) 2021-07-01
Series:Jornal Vascular Brasileiro
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1677-54492021000100624&tlng=en
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author Marta Wasilewska
author_facet Marta Wasilewska
author_sort Marta Wasilewska
collection DOAJ
description Abstract Chronic ulcerations of the lower extremities are quite a common condition amongst adults, most often caused by chronic venous insufficiency. Irrespective of the main underlying cause, chronic limb ulcerations are usually associated with significant symptoms, impairing daily functioning. Improper or delayed diagnosis and inadequate treatment increase the risk of serious complications, including limb amputations. Malignancies can develop secondary to chronic leg ulcers. About 2.4% of ulcers arising from chronic venous stasis undergo malignant transformation. Squamous cell carcinoma is the most common type of malignancy found in chronic leg ulceration biopsies. Basal cell carcinoma, sarcoma, and melanoma have all been documented infrequently. In the case described here, we found lymphoma of the marginal zone of mucosa-associated lymphoid tissue (MALT), which is an extremely rare cutaneous neoplasm of the lower extremities, but one that may have an association with autoimmune diseases.
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spelling doaj.art-3a6b57a883da4987a7c5b1f726f025472022-12-22T04:13:37ZengSociedade Brasileira de Angiologia e de Cirurgia Vascular (SBACV)Jornal Vascular Brasileiro1677-73012021-07-012010.1590/1677-5449.210003Atypical presentation of Sjogren’s syndrome with MALT lymphoma mimicking chronic venous ulcersMarta Wasilewskahttps://orcid.org/0000-0002-0220-4336Abstract Chronic ulcerations of the lower extremities are quite a common condition amongst adults, most often caused by chronic venous insufficiency. Irrespective of the main underlying cause, chronic limb ulcerations are usually associated with significant symptoms, impairing daily functioning. Improper or delayed diagnosis and inadequate treatment increase the risk of serious complications, including limb amputations. Malignancies can develop secondary to chronic leg ulcers. About 2.4% of ulcers arising from chronic venous stasis undergo malignant transformation. Squamous cell carcinoma is the most common type of malignancy found in chronic leg ulceration biopsies. Basal cell carcinoma, sarcoma, and melanoma have all been documented infrequently. In the case described here, we found lymphoma of the marginal zone of mucosa-associated lymphoid tissue (MALT), which is an extremely rare cutaneous neoplasm of the lower extremities, but one that may have an association with autoimmune diseases.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1677-54492021000100624&tlng=enleg ulcervenous insufficiencyskin neoplasmsSjogren’s syndromelymphoma
spellingShingle Marta Wasilewska
Atypical presentation of Sjogren’s syndrome with MALT lymphoma mimicking chronic venous ulcers
Jornal Vascular Brasileiro
leg ulcer
venous insufficiency
skin neoplasms
Sjogren’s syndrome
lymphoma
title Atypical presentation of Sjogren’s syndrome with MALT lymphoma mimicking chronic venous ulcers
title_full Atypical presentation of Sjogren’s syndrome with MALT lymphoma mimicking chronic venous ulcers
title_fullStr Atypical presentation of Sjogren’s syndrome with MALT lymphoma mimicking chronic venous ulcers
title_full_unstemmed Atypical presentation of Sjogren’s syndrome with MALT lymphoma mimicking chronic venous ulcers
title_short Atypical presentation of Sjogren’s syndrome with MALT lymphoma mimicking chronic venous ulcers
title_sort atypical presentation of sjogren s syndrome with malt lymphoma mimicking chronic venous ulcers
topic leg ulcer
venous insufficiency
skin neoplasms
Sjogren’s syndrome
lymphoma
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1677-54492021000100624&tlng=en
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