Biomarker identification and pathway analysis of Astragalus membranaceus and Curcuma zedoaria couplet medicines on adenine-induced chronic kidney disease in rats based on metabolomics

Biomarker identification and pathway analysis of Astragalus membranaceus and Curcuma zedoaria couplet medicines on adenine-induced chronic kidney disease in rats based on metabolomics

Background: Chronic kidney disease (CKD) is usually insidious, and most affected individuals are asymptomatic until the disease becomes advanced. The effective treatment of CKD would rely on the incorporation of multidisciplinary approaches. Astragalus membranaceus (AM) and Curcuma zedoaria (CZ) hav...

Full description

Bibliographic Details
Main Authors:	Lingfei Lu, Jiandong Lu, Jiwei Chen, Bing Wang, Hongcheng Peng, Jinting Peng, Xinhui Liu, Feng Lin, Guoliang Xiong
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2023-04-01
Series:	Frontiers in Pharmacology
Subjects:	Astragalus membranaceus Curcuma zedoaria chronic kidney disease metabolomic SIRT1/JNK signaling pathway
Online Access:	https://www.frontiersin.org/articles/10.3389/fphar.2023.1103527/full

Similar Items

Propagação "in vitro" de Curcuma zedoaria.
by: Fabrício Luiz Rezende, et al.
Published: (2007-06-01)

THE ANTiHYPOXIC PROPERTIES OF THE DRY EXTRACT OF ASTRAGALUS MEMBRANACEUS (FISH.) BUNGE
by: E. T. Batotsyrenova, et al.
Published: (2012-07-01)

Astragalus membranaceus (Huangqi) and Rhizoma curcumae (Ezhu) decoction suppresses colorectal cancer via downregulation of Wnt5/β-Catenin signal
by: Yong Bian, et al.
Published: (2022-01-01)

IDENTIFICATION OF ENDOPHYTIC BACTERIA FROM Curcuma zedoaria BASED ON PROTEIN PROFILE USING MALDI-TOF MASS SPECTROMETRY
by: Tri Ratna Sulistiyani, et al.
Published: (2018-09-01)

Characterization and phylogenetic analysis of the complete chloroplast genome of Curcuma zedoaria (Zingiberaceae)
by: Dong-Mei Li, et al.
Published: (2020-04-01)

Systematic Pharmacology and Experimental Validation to Reveal the Alleviation of Astragalus membranaceus Regulating Ferroptosis in Osteoarthritis
by: Chen K, et al.
Published: (2024-02-01)

The use of Astragalus membranaceus as an eco-friendly alternative for antibiotics in diets of Japanese quail breeders
by: Mahmoud Alagawany, et al.
Published: (2023-10-01)

Acute Toxicity of Ethanol Extract of Curcuma zedoaria Rosc (Zingiberaceae) Rhizomes on Brine Shrimp Larvae and Zebrafish Embryos
by: Gustini Syahbirin, et al.
Published: (2024-04-01)

Clinical effect of Astragalus membranaceus Injection on viral myocarditis in children: An overview of systematic reviews and evidence mapping
by: Xiaoshan Hui, et al.
Published: (2023-09-01)

A Network Pharmacology Prediction and Molecular Docking-Based Strategy to Explore the Potential Pharmacological Mechanism of <i>Astragalus membranaceus</i> for Glioma
by: Yu Feng, et al.
Published: (2023-11-01)

The modulatory properties of Astragalus membranaceus treatment on endometrial cancer: an integrated pharmacological method
by: Qianqian Zhang, et al.
Published: (2021-08-01)

Advances in Biotechnological Production and Metabolic Regulation of <i>Astragalus membranaceus</i>
by: Baoyu Ji, et al.
Published: (2023-04-01)

The Effects of Paeonia lactiflora Pall. and Astragalus Membranaceus Single Extracts on Bone Metabolic Profile in Ovariectomized Mice
by: Min Jung Park, et al.
Published: (2024-01-01)

<i>Astragalus membranaceus</i> (Huangqi) Supplementation in Sports Training: A Systematic Review
by: Michele Antonelli, et al.
Published: (2024-01-01)

Mechanism of Astragalus membranaceus in treatment for vascular dementia based on network pharmacology and molecular docking
by: XIONG Rui, et al.
Published: (2023-05-01)

Deciphering the Chemical Fingerprint of <i>Astragalus membranaceus</i>: Volatile Components Attractive to <i>Bruchophagus huonchili</i> Wasps
by: Chaoran Zhang, et al.
Published: (2023-10-01)

Beneficial Effects of <i>Astragalus membranaceus</i> (Fisch.) Bunge Extract in Controlling Inflammatory Response and Preventing Asthma Features
by: Danilo D’Avino, et al.
Published: (2023-06-01)

Biosynthesis and Pharmacological Activities of Flavonoids, Triterpene Saponins and Polysaccharides Derived from <i>Astragalus membranaceus</i>
by: Miaoyin Dong, et al.
Published: (2023-06-01)

Chemical constituents of Curcuma Zedoaria /
by: Rohaya Yatim, 1987-, et al.
Published: (2009)

Fermented Astragalus membranaceus could promote the liver and intestinal health of juvenile tiger grouper (Epinephelus fuscoguttatus)
by: Jingru Yang, et al.
Published: (2023-09-01)

Heterologous Expression of Three Transcription Factors Differently Regulated Astragalosides Metabolic Biosynthesis in <i>Astragalus membranaceus</i> Hairy Roots
by: Xiao Hua Li, et al.
Published: (2022-07-01)

Identification of oxidosqualene cyclases associated with saponin biosynthesis from Astragalus membranaceus reveals a conserved motif important for catalytic function
by: Kuan Chen, et al.
Published: (2023-01-01)

The ileal microbiome and mucosal immune profiles in response to dietary supplementation of ultra-grinded Astragalus membranaceus in weaned goats
by: Guowang Luo, et al.
Published: (2023-12-01)

Effect of <i>Astragalus membranaceus</i> Root on the Serum Metabolome of Preweaning Dairy Calves
by: Li Ma, et al.
Published: (2022-05-01)

Research on the interaction of astragaloside IV and calycosin in Astragalus membranaceus with HMGB1
by: Junyi Ye, et al.
Published: (2023-07-01)

Study on the Optimal Harvest Time of Stems and Leaves of Astragalus membranaceus Based on HPLC and Chemometrics
by: Xiaolan LI, et al.
Published: (2024-02-01)

Deciphering the Efficacy and Mechanism of <i>Astragalus membranaceus</i> on High Altitude Polycythemia by Integrating Network Pharmacology and In Vivo Experiments
by: Xiru Liu, et al.
Published: (2022-11-01)

Standardized astragalus extract for attenuation of the immunosuppression induced by strenuous physical exercise: randomized controlled trial
by: Ewa Latour, et al.
Published: (2021-07-01)

<i>Astragalus membranaceus</i> Extract Induces Apoptosis via Generation of Reactive Oxygen Species and Inhibition of Heat Shock Protein 27 and Androgen Receptor in Prostate Cancers
by: Seok-Young Kim, et al.
Published: (2024-02-01)

Effects of dietary Astragalus membranaceus and Codonopsis pilosula extracts on growth performance, antioxidant capacity, immune status, and intestinal health in broilers
by: Shun Liu, et al.
Published: (2023-12-01)

A Protective Role of Phenylalanine Ammonia-Lyase from <i>Astragalus membranaceus</i> against Saline-Alkali Stress
by: Lijuan Fan, et al.
Published: (2022-12-01)

Effects of Astragalus membranaceus extract and Eucommia ulmoides leaf extract on growth performance, blood biochemistry, and antioxidant capacity of gibel carp juveniles (Carassius auratus gibelio var. CAS V)
by: Yan Lin, et al.
Published: (2023-04-01)

High-Throughput Phytochemical Unscrambling of Flowers Originating from <i>Astragalus membranaceus</i> (Fisch.) Bge. var. <i>mongholicus</i> (Bge.) P. K. Hsiao and <i>Astragalus membranaceus</i> (Fisch.) Bug. by Applying the Intagretive Plant Metabolomics Method Using UHPLC−Q−TOF−MS/MS
by: Qi Liu, et al.
Published: (2023-08-01)

The Extract of <i>Astragalus membranaceus</i> Inhibits Lipid Oxidation in Fish Feed and Enhances Growth Performance and Antioxidant Capacity in Jian Carp (<i>Cyprinus carpio</i> var. Jian)
by: Jing Xu, et al.
Published: (2023-12-01)

Structure of a guaiane from curcuma zedoaria /
by: 245665 Isao Kouno, et al.

Anti-Oxidative and Anti-Inflammatory Activities of <i>Astragalus</i> <i>membranaceus</i> Fermented by <i>Lactiplantibacillus plantarum</i> on LPS-Induced RAW 264.7 Cells
by: Hye Min Park, et al.
Published: (2021-11-01)

Chemical constituents of Curcuma Heyneana and Curcuma Zedoaria /
by: Nurul Zulaikha Mohd. Yusoff, 1991-, author, et al.
Published: (2017)

Chemical constituents of Curcuma Heyneana and Curcuma Zedoaria /
by: Nurul Zulaikha Mohd. Yusoff, 1991-, author, et al.
Published: (2017)

Mechanism of <i>Astragalus membranaceus</i> Alleviating Acquired Hyperlipidemia Induced by High-Fat Diet through Regulating Lipid Metabolism
by: Ling Wang, et al.
Published: (2022-02-01)

Effect of Astragalus membranaceus on left ventricular remodeling in HFrEF: a systematic review and meta-analysis
by: Xu Han, et al.
Published: (2024-01-01)