Cellular and molecular mechanisms involved in the neuroprotective effects of VEGF on motoneurons

Cellular and molecular mechanisms involved in the neuroprotective effects of VEGF on motoneurons

Vascular endothelial growth factor (VEGF), originally described as a factor with a regulatory role in vascular growth and development, it is also known for its direct effects on neuronal cells. The discovery in the past decade that transgenic mice expressing reduced levels of VEGF developed late-ons...

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Bibliographic Details
Main Authors: Jerònia eLladó, Laia eTolosa, Gabriel eOlmos
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-10-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Akt
AMPA receptors
motoneuron
VEGF
ALS
excitotoxicity
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncel.2013.00181/full

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