Mortality Risk Factors in Patients with COVID-19 Infection: A Case-Control Study in Northeast of Iran

Background and Objectives: COVID-19 is a new disease and little information is available on its risk factors. The aim of this study was to determine the mortality risk factors in patients with COVID-19 in the northeast of Iran.     Materials and Methods: A case-control study was conducted. Patients...

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Main Authors: SA Hashemi, K Holakoui-Naeini, MA Mansournia, R Akrami, M Nomali, T Valadbeigi, V Mennati, HA Adineh, MR Taghavi, M Ghafouri, S Poorbarat, A Hoseinzadeh, M Farahdel, MR Armat, M Haresabadi
Format: Article
Language:fas
Published: Tehran University of Medical Sciences 2021-12-01
Series:مجله اپیدمیولوژی ایران
Subjects:
Online Access:http://irje.tums.ac.ir/article-1-7032-en.html
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author SA Hashemi
K Holakoui-Naeini
MA Mansournia
R Akrami
M Nomali
T Valadbeigi
V Mennati
HA Adineh
MR Taghavi
M Ghafouri
S Poorbarat
A Hoseinzadeh
M Farahdel
MR Armat
M Haresabadi
author_facet SA Hashemi
K Holakoui-Naeini
MA Mansournia
R Akrami
M Nomali
T Valadbeigi
V Mennati
HA Adineh
MR Taghavi
M Ghafouri
S Poorbarat
A Hoseinzadeh
M Farahdel
MR Armat
M Haresabadi
author_sort SA Hashemi
collection DOAJ
description Background and Objectives: COVID-19 is a new disease and little information is available on its risk factors. The aim of this study was to determine the mortality risk factors in patients with COVID-19 in the northeast of Iran.     Materials and Methods: A case-control study was conducted. Patients of both sexes with a confirmed diagnosis of Covid-19 infection who died during the study were studied as the case group and patients who were in good general health and ready for discharge were studied as the control group. Data analysis was performed with the STATA software version 14 using descriptive statistics and univariate and multiple logistic regression tests.   Results: Six hundred and eleven patients were studied (27% cases and 73% controls). Multiple logistic regression analysis showed that the odds of death were 2.8 times higher in patients over 80 years compared to patients aged 50-60 years. In addition, age under 40 years reduced the odds of mortality by 85% and living in rural areas increased odds of death by 2.2 times. Cough, general fatigue, pain, nausea and vomiting increased the odds of COVID19 survival.   Conclusion: The odds of mortality were higher in elder patients with COVID-19. In addition, living in rural areas increased the odds of mortality in patients. Cough and fatigue reduced mortality; however, it is needed to address other hidden factors for sound judgment.
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spelling doaj.art-3a7900df274444c6a4282974dcf382e72022-12-22T03:10:23ZfasTehran University of Medical Sciencesمجله اپیدمیولوژی ایران1735-74892228-75072021-12-01173224235Mortality Risk Factors in Patients with COVID-19 Infection: A Case-Control Study in Northeast of IranSA Hashemi0K Holakoui-Naeini1MA Mansournia2R Akrami3M Nomali4T Valadbeigi5V Mennati6HA Adineh7MR Taghavi8M Ghafouri9S Poorbarat10A Hoseinzadeh11M Farahdel12MR Armat13M Haresabadi14 Assistant Professor of Infectious Disease, Department of Infectious Diseases, School of Medicine, North KhorasanUniversity of Medical Sciences, Bojnurd, Iran PhD Professor, Department of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran Assistant Professor of Epidemilology, Department of Epidemiology, School of Public Health, Tehran University of Medical Sciences,Tehran, Iran - MSc of Epidemiology, Department of Epidemiology & Biostatistics, School of Public Health, Sabzevar University of Medical Sciences, Sabzevar, Iran;PhD Student of Epidemiology, Department of Epidemiology and Biostatistics, Tehran University of Medical Sciences, Tehran, Iran PhD Student of Epidemiology, Department of Epidemiology and Biostatistics, Tehran University of Medical Sciences, Tehran, Iran PhD Student of Epidemiology, Department of Epidemiology and Biostatistics, Tehran University of Medical Sciences, Tehran, Iran PhD Student of Epidemiology, Department of Epidemiology and Biostatistics, Tehran University of Medical Sciences, Tehran, Iran Epidemiologist, Iranshhar University of Medical Sciences, Iranshahr, Iran;PhD Student of Epidemiology, Department of Epidemiology and Biostatistics, Tehran University of Medical Sciences, Tehran, Iran Assistant Professor of Infectious Disease, Department of Infectious Diseases, School of Medicine, North KhorasanUniversity of Medical Sciences, Bojnurd, Iran Assistant Professor of Infectious Disease, Department of Infectious Diseases, School of Medicine, North KhorasanUniversity of Medical Sciences, Bojnurd, Iran Student Research Committee, North Khorasan University of Medical Sciences, Bojnurd, Iran Student Research Committee, North Khorasan University of Medical Sciences, Bojnurd, Iran MSc in Critical Care nursing, Imam Hassan Hospital, North Khorasan University of Medical Sciences, Bojnurd, Iran Assistant Professor of Nursing, School of Nursing, North Khorasan University of Medical Sciences, Bojnurd, Iran Instructor of Community Health Nursing, Department of Nursing, School of Nursing and, North Khorasan University of Medical Sciences, Bojnurd, Iran; PhD Student of Epidemiology, Department of Epidemiology and Biostatistics, Tehran University of Medical Sciences, Tehran, Iran Background and Objectives: COVID-19 is a new disease and little information is available on its risk factors. The aim of this study was to determine the mortality risk factors in patients with COVID-19 in the northeast of Iran.     Materials and Methods: A case-control study was conducted. Patients of both sexes with a confirmed diagnosis of Covid-19 infection who died during the study were studied as the case group and patients who were in good general health and ready for discharge were studied as the control group. Data analysis was performed with the STATA software version 14 using descriptive statistics and univariate and multiple logistic regression tests.   Results: Six hundred and eleven patients were studied (27% cases and 73% controls). Multiple logistic regression analysis showed that the odds of death were 2.8 times higher in patients over 80 years compared to patients aged 50-60 years. In addition, age under 40 years reduced the odds of mortality by 85% and living in rural areas increased odds of death by 2.2 times. Cough, general fatigue, pain, nausea and vomiting increased the odds of COVID19 survival.   Conclusion: The odds of mortality were higher in elder patients with COVID-19. In addition, living in rural areas increased the odds of mortality in patients. Cough and fatigue reduced mortality; however, it is needed to address other hidden factors for sound judgment.http://irje.tums.ac.ir/article-1-7032-en.htmlrisk factorsmortalitycovid-19case-control studyiran
spellingShingle SA Hashemi
K Holakoui-Naeini
MA Mansournia
R Akrami
M Nomali
T Valadbeigi
V Mennati
HA Adineh
MR Taghavi
M Ghafouri
S Poorbarat
A Hoseinzadeh
M Farahdel
MR Armat
M Haresabadi
Mortality Risk Factors in Patients with COVID-19 Infection: A Case-Control Study in Northeast of Iran
مجله اپیدمیولوژی ایران
risk factors
mortality
covid-19
case-control study
iran
title Mortality Risk Factors in Patients with COVID-19 Infection: A Case-Control Study in Northeast of Iran
title_full Mortality Risk Factors in Patients with COVID-19 Infection: A Case-Control Study in Northeast of Iran
title_fullStr Mortality Risk Factors in Patients with COVID-19 Infection: A Case-Control Study in Northeast of Iran
title_full_unstemmed Mortality Risk Factors in Patients with COVID-19 Infection: A Case-Control Study in Northeast of Iran
title_short Mortality Risk Factors in Patients with COVID-19 Infection: A Case-Control Study in Northeast of Iran
title_sort mortality risk factors in patients with covid 19 infection a case control study in northeast of iran
topic risk factors
mortality
covid-19
case-control study
iran
url http://irje.tums.ac.ir/article-1-7032-en.html
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