Evaluation of 55 Cases with Spondylodiscitis Due to Brucellosis
Introduction: The aim of this study was to evaluate the demographic, clinical, and laboratory findings of 55 cases diagnosed as spondylodiscitis due to brucellosis. Materials and Methods: This study was performed between 1 January 2010 and 31 December 2011. It included patients over 18 years of age...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | Turkish |
| Published: |
Galenos Yayinevi
2013-12-01
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| Series: | Mediterranean Journal of Infection, Microbes and Antimicrobials |
| Subjects: | |
| Online Access: | http://www.mjima.org/pdf.php?&id=17 |
| _version_ | 1797913249863172096 |
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| author | Servet KÖLGELİER Nazlım AKTUĞ DEMİR Aykut AKPINAR Serap ÖZÇİMEN Lütfi Saltuk DEMİR Adem YILDIRIM Şua SÜMER |
| author_facet | Servet KÖLGELİER Nazlım AKTUĞ DEMİR Aykut AKPINAR Serap ÖZÇİMEN Lütfi Saltuk DEMİR Adem YILDIRIM Şua SÜMER |
| author_sort | Servet KÖLGELİER |
| collection | DOAJ |
| description | Introduction: The aim of this study was to evaluate the demographic, clinical, and laboratory findings of 55 cases diagnosed as spondylodiscitis due to brucellosis.
Materials and Methods: This study was performed between 1 January 2010 and 31 December 2011. It included patients over 18 years of age who were diagnosed as spondylodiscitis by neurosurgery and physical medicine and rehabilitation specialists in the presence of clinical findings (a titer ≥1/160 in standard tube agglutination (STA) and/or growth of Brucella spp. in appropriately obtained cultures) in addition to magnetic resonance imaging (MRI) findings. Patient charts, which included age, sex, laboratory culture results, treatment protocols, and radiographic findings, were evaluated retrospectively. Data were recorded to the SPSS 16.0 package program, and descriptive statistics and Mann-Whitney U tests were used. A p value <0.05 was considered statistically significant.
Results: Thirty-two (58.2%) patients were male and 23 (41.8%) were female. The most common three findings were lower back pain (100%), fever (83.6%) and night sweats (81.8%). Lumbar vertebra involvement was detected in 50 patients, thoracal vertebra involvement in 4 and cervical vertebra involvement in 1. Multiple discs were involved in 17 patients. When we evaluated patients according to gender, fatigue was more frequent in females (p=0.046), the mean age of males was higher (p=0.018), and multiple disc involvement was more frequent in males (p=0.04). The most frequently involved vertebrae were L4-5. Follow-up MRIs of 36 patients could be obtained at the 12th week of treatment. Inflammation and edema in the disc space had increased in 6 (16.6%), decreased in 20 (55.6%), and were unchanged in 10 (27.8%) patients.
Conclusion: Spondylodiscitis can be observed as a result of musculoskeletal involvement, which is the most common complication of brucellosis, and the lumbar region is the most frequently affected. In spinal brucellosis, first the vertebra corpus is involved, then spread to the neighboring disc space and vertebra corpus is observed, and with disc involvement, spondylitis evolves into spondylodiscitis. Brucellosis should be considered in the differential diagnosis in the presence of fever and lower back symptoms, especially in patients living in endemic regions. |
| first_indexed | 2024-04-10T12:08:57Z |
| format | Article |
| id | doaj.art-3a79723ca3b44bcb8ea0130b0f3db997 |
| institution | Directory Open Access Journal |
| issn | 2147-673X |
| language | Turkish |
| last_indexed | 2024-04-10T12:08:57Z |
| publishDate | 2013-12-01 |
| publisher | Galenos Yayinevi |
| record_format | Article |
| series | Mediterranean Journal of Infection, Microbes and Antimicrobials |
| spelling | doaj.art-3a79723ca3b44bcb8ea0130b0f3db9972023-02-15T16:16:04ZturGalenos YayineviMediterranean Journal of Infection, Microbes and Antimicrobials2147-673X2013-12-012Evaluation of 55 Cases with Spondylodiscitis Due to BrucellosisServet KÖLGELİER0Nazlım AKTUĞ DEMİR1Aykut AKPINAR2Serap ÖZÇİMEN3Lütfi Saltuk DEMİR4Adem YILDIRIM5Şua SÜMER6Adıyaman 82. Yıl Devlet Hastanesi, Enfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Kliniği, Adıyaman, TürkiyeKonya Eğitim ve Araştırma Hastanesi, Enfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Kliniği, Konya, TürkiyeAdıyaman Devlet Hastanesi, Beyin Cerrahisi Kliniği, Adıyaman, TürkiyeKonya Numune Hastanesi, Enfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Kliniği, Konya, TürkiyeKonya Halk Sağlığı Müdürlüğü, Halk Sağlığı Bölümü, Konya,TürkiyeAdıyaman Devlet Hastanesi, Fizik Tedavi ve Rehabilitasyon Kliniği, Adıyaman, TürkiyeSelçuk Üniversitesi Selçuklu Tıp Fakültesi, Enfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Anabilim Dalı, Konya, TürkiyeIntroduction: The aim of this study was to evaluate the demographic, clinical, and laboratory findings of 55 cases diagnosed as spondylodiscitis due to brucellosis. Materials and Methods: This study was performed between 1 January 2010 and 31 December 2011. It included patients over 18 years of age who were diagnosed as spondylodiscitis by neurosurgery and physical medicine and rehabilitation specialists in the presence of clinical findings (a titer ≥1/160 in standard tube agglutination (STA) and/or growth of Brucella spp. in appropriately obtained cultures) in addition to magnetic resonance imaging (MRI) findings. Patient charts, which included age, sex, laboratory culture results, treatment protocols, and radiographic findings, were evaluated retrospectively. Data were recorded to the SPSS 16.0 package program, and descriptive statistics and Mann-Whitney U tests were used. A p value <0.05 was considered statistically significant. Results: Thirty-two (58.2%) patients were male and 23 (41.8%) were female. The most common three findings were lower back pain (100%), fever (83.6%) and night sweats (81.8%). Lumbar vertebra involvement was detected in 50 patients, thoracal vertebra involvement in 4 and cervical vertebra involvement in 1. Multiple discs were involved in 17 patients. When we evaluated patients according to gender, fatigue was more frequent in females (p=0.046), the mean age of males was higher (p=0.018), and multiple disc involvement was more frequent in males (p=0.04). The most frequently involved vertebrae were L4-5. Follow-up MRIs of 36 patients could be obtained at the 12th week of treatment. Inflammation and edema in the disc space had increased in 6 (16.6%), decreased in 20 (55.6%), and were unchanged in 10 (27.8%) patients. Conclusion: Spondylodiscitis can be observed as a result of musculoskeletal involvement, which is the most common complication of brucellosis, and the lumbar region is the most frequently affected. In spinal brucellosis, first the vertebra corpus is involved, then spread to the neighboring disc space and vertebra corpus is observed, and with disc involvement, spondylitis evolves into spondylodiscitis. Brucellosis should be considered in the differential diagnosis in the presence of fever and lower back symptoms, especially in patients living in endemic regions.http://www.mjima.org/pdf.php?&id=17Brucellosisspondylodiscitiszoonotic diseases |
| spellingShingle | Servet KÖLGELİER Nazlım AKTUĞ DEMİR Aykut AKPINAR Serap ÖZÇİMEN Lütfi Saltuk DEMİR Adem YILDIRIM Şua SÜMER Evaluation of 55 Cases with Spondylodiscitis Due to Brucellosis Mediterranean Journal of Infection, Microbes and Antimicrobials Brucellosis spondylodiscitis zoonotic diseases |
| title | Evaluation of 55 Cases with Spondylodiscitis Due to Brucellosis |
| title_full | Evaluation of 55 Cases with Spondylodiscitis Due to Brucellosis |
| title_fullStr | Evaluation of 55 Cases with Spondylodiscitis Due to Brucellosis |
| title_full_unstemmed | Evaluation of 55 Cases with Spondylodiscitis Due to Brucellosis |
| title_short | Evaluation of 55 Cases with Spondylodiscitis Due to Brucellosis |
| title_sort | evaluation of 55 cases with spondylodiscitis due to brucellosis |
| topic | Brucellosis spondylodiscitis zoonotic diseases |
| url | http://www.mjima.org/pdf.php?&id=17 |
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