СARDIOPROTECTION IN PATIENTS WITH HYPERTENSION – THE ROLE OF LOSARTAN
In patients with arterial hypertension (HT) heart is affected earlier and more often than other target organs, left ventricular hypertrophy (LVH) develops. Considering the proven link between the presence of LVH and increased cardiovascular risk, the deterioration of the clinical course and prognosi...
Main Authors: | , |
---|---|
Format: | Article |
Language: | English |
Published: |
Столичная издательская компания
2015-09-01
|
Series: | Рациональная фармакотерапия в кардиологии |
Subjects: | |
Online Access: | https://www.rpcardio.online/jour/article/view/277 |
_version_ | 1797232441741541376 |
---|---|
author | I. I. Chukaeva Ya. G. Spiryakina |
author_facet | I. I. Chukaeva Ya. G. Spiryakina |
author_sort | I. I. Chukaeva |
collection | DOAJ |
description | In patients with arterial hypertension (HT) heart is affected earlier and more often than other target organs, left ventricular hypertrophy (LVH) develops. Considering the proven link between the presence of LVH and increased cardiovascular risk, the deterioration of the clinical course and prognosis in HT patients, as well as a significant prognosis improvement in patients with LVH decrease, correction of modifiable risk factors (including uncontrolled HT) is getting extremely important. Organoprotective properties of drugs should be taken into account as one of the important parameters in the consideration of antihypertensive therapy. Major studies conducted in recent years have proven cardioprotective and angioprotective properties of angiotensin receptor blocker losartan, so it can be used as first-line therapy in patients with HT and LVH. |
first_indexed | 2024-03-08T14:05:48Z |
format | Article |
id | doaj.art-3a7fe54f13474b9e83cabe3163181c97 |
institution | Directory Open Access Journal |
issn | 1819-6446 2225-3653 |
language | English |
last_indexed | 2024-04-24T16:00:20Z |
publishDate | 2015-09-01 |
publisher | Столичная издательская компания |
record_format | Article |
series | Рациональная фармакотерапия в кардиологии |
spelling | doaj.art-3a7fe54f13474b9e83cabe3163181c972024-04-01T07:43:23ZengСтоличная издательская компанияРациональная фармакотерапия в кардиологии1819-64462225-36532015-09-019666066310.20996/1819-6446-2013-9-6-660-663277СARDIOPROTECTION IN PATIENTS WITH HYPERTENSION – THE ROLE OF LOSARTANI. I. Chukaeva0Ya. G. Spiryakina1Russian National Research Medical University named after N.I. Pirogov, MoscowRussian National Research Medical University named after N.I. Pirogov, MoscowIn patients with arterial hypertension (HT) heart is affected earlier and more often than other target organs, left ventricular hypertrophy (LVH) develops. Considering the proven link between the presence of LVH and increased cardiovascular risk, the deterioration of the clinical course and prognosis in HT patients, as well as a significant prognosis improvement in patients with LVH decrease, correction of modifiable risk factors (including uncontrolled HT) is getting extremely important. Organoprotective properties of drugs should be taken into account as one of the important parameters in the consideration of antihypertensive therapy. Major studies conducted in recent years have proven cardioprotective and angioprotective properties of angiotensin receptor blocker losartan, so it can be used as first-line therapy in patients with HT and LVH.https://www.rpcardio.online/jour/article/view/277arterial hypertensionleft ventricular hypertrophyantihypertensive therapycardioprotectionlosartan |
spellingShingle | I. I. Chukaeva Ya. G. Spiryakina СARDIOPROTECTION IN PATIENTS WITH HYPERTENSION – THE ROLE OF LOSARTAN Рациональная фармакотерапия в кардиологии arterial hypertension left ventricular hypertrophy antihypertensive therapy cardioprotection losartan |
title | СARDIOPROTECTION IN PATIENTS WITH HYPERTENSION – THE ROLE OF LOSARTAN |
title_full | СARDIOPROTECTION IN PATIENTS WITH HYPERTENSION – THE ROLE OF LOSARTAN |
title_fullStr | СARDIOPROTECTION IN PATIENTS WITH HYPERTENSION – THE ROLE OF LOSARTAN |
title_full_unstemmed | СARDIOPROTECTION IN PATIENTS WITH HYPERTENSION – THE ROLE OF LOSARTAN |
title_short | СARDIOPROTECTION IN PATIENTS WITH HYPERTENSION – THE ROLE OF LOSARTAN |
title_sort | сardioprotection in patients with hypertension the role of losartan |
topic | arterial hypertension left ventricular hypertrophy antihypertensive therapy cardioprotection losartan |
url | https://www.rpcardio.online/jour/article/view/277 |
work_keys_str_mv | AT iichukaeva sardioprotectioninpatientswithhypertensiontheroleoflosartan AT yagspiryakina sardioprotectioninpatientswithhypertensiontheroleoflosartan |