Mood Disorders and Severity of Addiction in Alcohol-Dependent Patients Could Be Mediated by Sex Differences

Background: Alcohol dependence is highly prevalent in the general population; some differences in alcohol use and dependence between women and men have been described, including outcomes and ranging from biological to social variables. This study aims to compare the severity of alcohol dependence wi...

Full description

Bibliographic Details
Main Authors: Raul F. Palma-Álvarez, Laia Rodríguez-Cintas, Alfonso C. Abad, Marta Sorribes, Elena Ros-Cucurull, María Robles-Martínez, Lara Grau-López, Lourdes Aguilar, Carlos Roncero
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-05-01
Series:Frontiers in Psychiatry
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fpsyt.2019.00343/full
_version_ 1819097861378277376
author Raul F. Palma-Álvarez
Raul F. Palma-Álvarez
Laia Rodríguez-Cintas
Laia Rodríguez-Cintas
Alfonso C. Abad
Marta Sorribes
Elena Ros-Cucurull
Elena Ros-Cucurull
María Robles-Martínez
Lara Grau-López
Lara Grau-López
Lourdes Aguilar
Carlos Roncero
author_facet Raul F. Palma-Álvarez
Raul F. Palma-Álvarez
Laia Rodríguez-Cintas
Laia Rodríguez-Cintas
Alfonso C. Abad
Marta Sorribes
Elena Ros-Cucurull
Elena Ros-Cucurull
María Robles-Martínez
Lara Grau-López
Lara Grau-López
Lourdes Aguilar
Carlos Roncero
author_sort Raul F. Palma-Álvarez
collection DOAJ
description Background: Alcohol dependence is highly prevalent in the general population; some differences in alcohol use and dependence between women and men have been described, including outcomes and ranging from biological to social variables. This study aims to compare the severity of alcohol dependence with clinical and psychopathological characteristics between sexes.Methods: A cross-sectional descriptive study was conducted in alcohol-dependent outpatients; the recruitment period was 7 years. The assessment of these patients was carried out by obtaining sociodemographic characteristics and using the Semi-structured Clinical Interview for Axis I and II (SCID-I and SCID-II), European version of the Addiction Severity Index (EuropASI), Beck Depression Inventory (BDI), and State–Trait Anxiety Inventory (STAI) scales. Variables were compared and analyzed.Results: The sample was composed of 178 patients (74.2% males and 25.8% females) with a mean age of 46.52 ± 9.86. No sociodemographic differences were found between men and women. Females had a higher rate of suicide attempts and depression symptoms at the treatment onset. When results of EuropASI were compared, females had worse psychological and employment results than males. According to consumption variables, males had an earlier onset of alcohol use, had more regular alcohol use, and develop alcohol dependence earlier than females.Conclusions: According to results, there are sex-dependent differences (severity and other variables such as mood or suicide) in alcohol dependence. Thus, this may implicate the need of future specific research and treatment programs based on the specific necessities of each sex.
first_indexed 2024-12-22T00:21:49Z
format Article
id doaj.art-3a81e322b72147859e6a9eacd68d3c61
institution Directory Open Access Journal
issn 1664-0640
language English
last_indexed 2024-12-22T00:21:49Z
publishDate 2019-05-01
publisher Frontiers Media S.A.
record_format Article
series Frontiers in Psychiatry
spelling doaj.art-3a81e322b72147859e6a9eacd68d3c612022-12-21T18:45:08ZengFrontiers Media S.A.Frontiers in Psychiatry1664-06402019-05-011010.3389/fpsyt.2019.00343425478Mood Disorders and Severity of Addiction in Alcohol-Dependent Patients Could Be Mediated by Sex DifferencesRaul F. Palma-Álvarez0Raul F. Palma-Álvarez1Laia Rodríguez-Cintas2Laia Rodríguez-Cintas3Alfonso C. Abad4Marta Sorribes5Elena Ros-Cucurull6Elena Ros-Cucurull7María Robles-Martínez8Lara Grau-López9Lara Grau-López10Lourdes Aguilar11Carlos Roncero12Addiction and Dual Diagnosis Unit, Department of Psychiatry, Vall d’Hebron University Hospital–Public Health Agency, Barcelona (ASPB), CIBERSAM, Barcelona, SpainDepartment of Psychiatry and Legal Medicine, Universitat Autònomade Barcelona, Barcelona, SpainAddiction and Dual Diagnosis Unit, Department of Psychiatry, Vall d’Hebron University Hospital–Public Health Agency, Barcelona (ASPB), CIBERSAM, Barcelona, SpainDepartment of Psychiatry and Legal Medicine, Universitat Autònomade Barcelona, Barcelona, SpainAddiction and Dual Diagnosis Unit, Department of Psychiatry, Vall d’Hebron University Hospital–Public Health Agency, Barcelona (ASPB), CIBERSAM, Barcelona, SpainAddiction and Dual Diagnosis Unit, Department of Psychiatry, Vall d’Hebron University Hospital–Public Health Agency, Barcelona (ASPB), CIBERSAM, Barcelona, SpainAddiction and Dual Diagnosis Unit, Department of Psychiatry, Vall d’Hebron University Hospital–Public Health Agency, Barcelona (ASPB), CIBERSAM, Barcelona, SpainDepartment of Psychiatry and Legal Medicine, Universitat Autònomade Barcelona, Barcelona, SpainInstitutde Neuropsiquiatria i Addiccions, Hospital del Mar, Barcelona, SpainAddiction and Dual Diagnosis Unit, Department of Psychiatry, Vall d’Hebron University Hospital–Public Health Agency, Barcelona (ASPB), CIBERSAM, Barcelona, SpainDepartment of Psychiatry and Legal Medicine, Universitat Autònomade Barcelona, Barcelona, SpainPsychiatry Service, Salamanca University Health Care Complex, Institute of Biomedicine, University of Salamanca, Salamanca, SpainPsychiatry Service, Salamanca University Health Care Complex, Institute of Biomedicine, University of Salamanca, Salamanca, SpainBackground: Alcohol dependence is highly prevalent in the general population; some differences in alcohol use and dependence between women and men have been described, including outcomes and ranging from biological to social variables. This study aims to compare the severity of alcohol dependence with clinical and psychopathological characteristics between sexes.Methods: A cross-sectional descriptive study was conducted in alcohol-dependent outpatients; the recruitment period was 7 years. The assessment of these patients was carried out by obtaining sociodemographic characteristics and using the Semi-structured Clinical Interview for Axis I and II (SCID-I and SCID-II), European version of the Addiction Severity Index (EuropASI), Beck Depression Inventory (BDI), and State–Trait Anxiety Inventory (STAI) scales. Variables were compared and analyzed.Results: The sample was composed of 178 patients (74.2% males and 25.8% females) with a mean age of 46.52 ± 9.86. No sociodemographic differences were found between men and women. Females had a higher rate of suicide attempts and depression symptoms at the treatment onset. When results of EuropASI were compared, females had worse psychological and employment results than males. According to consumption variables, males had an earlier onset of alcohol use, had more regular alcohol use, and develop alcohol dependence earlier than females.Conclusions: According to results, there are sex-dependent differences (severity and other variables such as mood or suicide) in alcohol dependence. Thus, this may implicate the need of future specific research and treatment programs based on the specific necessities of each sex.https://www.frontiersin.org/article/10.3389/fpsyt.2019.00343/fullalcoholdependencedepressionsuicide attemptsseveritysex differences
spellingShingle Raul F. Palma-Álvarez
Raul F. Palma-Álvarez
Laia Rodríguez-Cintas
Laia Rodríguez-Cintas
Alfonso C. Abad
Marta Sorribes
Elena Ros-Cucurull
Elena Ros-Cucurull
María Robles-Martínez
Lara Grau-López
Lara Grau-López
Lourdes Aguilar
Carlos Roncero
Mood Disorders and Severity of Addiction in Alcohol-Dependent Patients Could Be Mediated by Sex Differences
Frontiers in Psychiatry
alcohol
dependence
depression
suicide attempts
severity
sex differences
title Mood Disorders and Severity of Addiction in Alcohol-Dependent Patients Could Be Mediated by Sex Differences
title_full Mood Disorders and Severity of Addiction in Alcohol-Dependent Patients Could Be Mediated by Sex Differences
title_fullStr Mood Disorders and Severity of Addiction in Alcohol-Dependent Patients Could Be Mediated by Sex Differences
title_full_unstemmed Mood Disorders and Severity of Addiction in Alcohol-Dependent Patients Could Be Mediated by Sex Differences
title_short Mood Disorders and Severity of Addiction in Alcohol-Dependent Patients Could Be Mediated by Sex Differences
title_sort mood disorders and severity of addiction in alcohol dependent patients could be mediated by sex differences
topic alcohol
dependence
depression
suicide attempts
severity
sex differences
url https://www.frontiersin.org/article/10.3389/fpsyt.2019.00343/full
work_keys_str_mv AT raulfpalmaalvarez mooddisordersandseverityofaddictioninalcoholdependentpatientscouldbemediatedbysexdifferences
AT raulfpalmaalvarez mooddisordersandseverityofaddictioninalcoholdependentpatientscouldbemediatedbysexdifferences
AT laiarodriguezcintas mooddisordersandseverityofaddictioninalcoholdependentpatientscouldbemediatedbysexdifferences
AT laiarodriguezcintas mooddisordersandseverityofaddictioninalcoholdependentpatientscouldbemediatedbysexdifferences
AT alfonsocabad mooddisordersandseverityofaddictioninalcoholdependentpatientscouldbemediatedbysexdifferences
AT martasorribes mooddisordersandseverityofaddictioninalcoholdependentpatientscouldbemediatedbysexdifferences
AT elenaroscucurull mooddisordersandseverityofaddictioninalcoholdependentpatientscouldbemediatedbysexdifferences
AT elenaroscucurull mooddisordersandseverityofaddictioninalcoholdependentpatientscouldbemediatedbysexdifferences
AT mariaroblesmartinez mooddisordersandseverityofaddictioninalcoholdependentpatientscouldbemediatedbysexdifferences
AT laragraulopez mooddisordersandseverityofaddictioninalcoholdependentpatientscouldbemediatedbysexdifferences
AT laragraulopez mooddisordersandseverityofaddictioninalcoholdependentpatientscouldbemediatedbysexdifferences
AT lourdesaguilar mooddisordersandseverityofaddictioninalcoholdependentpatientscouldbemediatedbysexdifferences
AT carlosroncero mooddisordersandseverityofaddictioninalcoholdependentpatientscouldbemediatedbysexdifferences