Contact hypersensitivity to nickel in patients with atopic dermatitis
Atopic dermatitis is a chronic, recurrent inflammatory dermatosis with a complex and not fully explained pathogenesis. Recent years’ research points to a significant percentage of patients with atopic eczema in whom hapten patch test results are positive, especially with respect to nickel. These obs...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Termedia Publishing House
2017-04-01
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| Series: | Przegląd Dermatologiczny |
| Subjects: | |
| Online Access: | https://www.termedia.pl/Contact-hypersensitivity-to-nickel-in-patients-with-atopic-dermatitis,56,29865,1,1.html |
| _version_ | 1818519331103834112 |
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| author | Michał Rożalski Leszek Blicharz Zbigniew Samochocki |
| author_facet | Michał Rożalski Leszek Blicharz Zbigniew Samochocki |
| author_sort | Michał Rożalski |
| collection | DOAJ |
| description | Atopic dermatitis is a chronic, recurrent inflammatory dermatosis with a complex and not fully explained pathogenesis. Recent years’ research points to a significant percentage of patients with atopic eczema in whom hapten patch test results are positive, especially with respect to nickel. These observations undermine suggestions that contact allergy (type IV hypersensitivity) is rare in this group due to the dominance of the Th2-type cellular response characteristic for type I allergic reactions. In this review we aimed to systematize current knowledge regarding the pathomechanisms of contact hypersensitivity to nickel in patients with atopic dermatitis and the potential influence of this hapten on the clinical course of the disease. |
| first_indexed | 2024-12-11T01:22:52Z |
| format | Article |
| id | doaj.art-3a832073f605439eb8fb6abec11c97da |
| institution | Directory Open Access Journal |
| issn | 0033-2526 2084-9893 |
| language | English |
| last_indexed | 2024-12-11T01:22:52Z |
| publishDate | 2017-04-01 |
| publisher | Termedia Publishing House |
| record_format | Article |
| series | Przegląd Dermatologiczny |
| spelling | doaj.art-3a832073f605439eb8fb6abec11c97da2022-12-22T01:25:40ZengTermedia Publishing HousePrzegląd Dermatologiczny0033-25262084-98932017-04-01104213314110.5114/dr.2017.6738829865Contact hypersensitivity to nickel in patients with atopic dermatitisMichał RożalskiLeszek BlicharzZbigniew SamochockiAtopic dermatitis is a chronic, recurrent inflammatory dermatosis with a complex and not fully explained pathogenesis. Recent years’ research points to a significant percentage of patients with atopic eczema in whom hapten patch test results are positive, especially with respect to nickel. These observations undermine suggestions that contact allergy (type IV hypersensitivity) is rare in this group due to the dominance of the Th2-type cellular response characteristic for type I allergic reactions. In this review we aimed to systematize current knowledge regarding the pathomechanisms of contact hypersensitivity to nickel in patients with atopic dermatitis and the potential influence of this hapten on the clinical course of the disease.https://www.termedia.pl/Contact-hypersensitivity-to-nickel-in-patients-with-atopic-dermatitis,56,29865,1,1.htmlatopic dermatitis allergic contact dermatitis nickel |
| spellingShingle | Michał Rożalski Leszek Blicharz Zbigniew Samochocki Contact hypersensitivity to nickel in patients with atopic dermatitis Przegląd Dermatologiczny atopic dermatitis allergic contact dermatitis nickel |
| title | Contact hypersensitivity to nickel in patients with atopic dermatitis |
| title_full | Contact hypersensitivity to nickel in patients with atopic dermatitis |
| title_fullStr | Contact hypersensitivity to nickel in patients with atopic dermatitis |
| title_full_unstemmed | Contact hypersensitivity to nickel in patients with atopic dermatitis |
| title_short | Contact hypersensitivity to nickel in patients with atopic dermatitis |
| title_sort | contact hypersensitivity to nickel in patients with atopic dermatitis |
| topic | atopic dermatitis allergic contact dermatitis nickel |
| url | https://www.termedia.pl/Contact-hypersensitivity-to-nickel-in-patients-with-atopic-dermatitis,56,29865,1,1.html |
| work_keys_str_mv | AT michałrozalski contacthypersensitivitytonickelinpatientswithatopicdermatitis AT leszekblicharz contacthypersensitivitytonickelinpatientswithatopicdermatitis AT zbigniewsamochocki contacthypersensitivitytonickelinpatientswithatopicdermatitis |