Preoperative Evaluation through Dermoscopy and Reflectance Confocal Microscopy of the Lateral Excision Margins for Primary Basal Cell Carcinoma
Complete removal of malignant skin lesions with minimal impact on the aesthetic and functional aspects is the ideal of every dermatologic surgeon. Incomplete surgical excisions and tumor recurrences of basal cell carcinomas (BCC) commonly occur due to the subclinical extension of tumor lateral margi...
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-01-01
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| Series: | Diagnostics |
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| Online Access: | https://www.mdpi.com/2075-4418/11/1/120 |
| _version_ | 1797411886844608512 |
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| author | Mihai Lupu Vlad Mihai Voiculescu Ana Caruntu Tiberiu Tebeica Constantin Caruntu |
| author_facet | Mihai Lupu Vlad Mihai Voiculescu Ana Caruntu Tiberiu Tebeica Constantin Caruntu |
| author_sort | Mihai Lupu |
| collection | DOAJ |
| description | Complete removal of malignant skin lesions with minimal impact on the aesthetic and functional aspects is the ideal of every dermatologic surgeon. Incomplete surgical excisions and tumor recurrences of basal cell carcinomas (BCC) commonly occur due to the subclinical extension of tumor lateral margins. Presently, the lateral excision margins for BCC cannot be objectively assessed preoperatively, dermoscopy proving to be relatively inefficient in this respect. The question is whether BCC lateral excision margins can be precisely determined preoperatively through the use of complementary non-invasive imaging techniques such as dermoscopy and reflectance confocal microscopy (RCM), thus permitting the complete removal of the lesion in a single stage, estimation of the post-excisional defect, and planning an appropriate reconstruction, especially in medical centers where Mohs micrographic surgery is not available. We present the results of a prospective, histopathologically controlled study designed to determine the feasibility of preoperative, non-invasive, in vivo evaluation of the lateral excision margins for primary basal cell carcinoma, through dermoscopy and RCM. |
| first_indexed | 2024-03-09T04:52:44Z |
| format | Article |
| id | doaj.art-3a838771da8840809840fd8d507a22a4 |
| institution | Directory Open Access Journal |
| issn | 2075-4418 |
| language | English |
| last_indexed | 2024-03-09T04:52:44Z |
| publishDate | 2021-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Diagnostics |
| spelling | doaj.art-3a838771da8840809840fd8d507a22a42023-12-03T13:08:53ZengMDPI AGDiagnostics2075-44182021-01-0111112010.3390/diagnostics11010120Preoperative Evaluation through Dermoscopy and Reflectance Confocal Microscopy of the Lateral Excision Margins for Primary Basal Cell CarcinomaMihai Lupu0Vlad Mihai Voiculescu1Ana Caruntu2Tiberiu Tebeica3Constantin Caruntu4Dermatology Research Laboratory, “Carol Davila” University of Medicine and Pharmacy, 050474 Bucharest, RomaniaDermatology Research Laboratory, “Carol Davila” University of Medicine and Pharmacy, 050474 Bucharest, RomaniaDepartment of Oral and Maxillofacial Surgery, “Carol Davila” Central Military Emergency Hospital, 010825 Bucharest, RomaniaDepartment of Histopathology, “Dr. Leventer Centre”, 011216 Bucharest, RomaniaDepartment of Dermatology, “Prof. N.C. Paulescu” National Institute of Diabetes, Nutrition and Metabolic Diseases, 011233 Bucharest, RomaniaComplete removal of malignant skin lesions with minimal impact on the aesthetic and functional aspects is the ideal of every dermatologic surgeon. Incomplete surgical excisions and tumor recurrences of basal cell carcinomas (BCC) commonly occur due to the subclinical extension of tumor lateral margins. Presently, the lateral excision margins for BCC cannot be objectively assessed preoperatively, dermoscopy proving to be relatively inefficient in this respect. The question is whether BCC lateral excision margins can be precisely determined preoperatively through the use of complementary non-invasive imaging techniques such as dermoscopy and reflectance confocal microscopy (RCM), thus permitting the complete removal of the lesion in a single stage, estimation of the post-excisional defect, and planning an appropriate reconstruction, especially in medical centers where Mohs micrographic surgery is not available. We present the results of a prospective, histopathologically controlled study designed to determine the feasibility of preoperative, non-invasive, in vivo evaluation of the lateral excision margins for primary basal cell carcinoma, through dermoscopy and RCM.https://www.mdpi.com/2075-4418/11/1/120carcinomabasal cellmicroscopyconfocaldermoscopyprospective studies |
| spellingShingle | Mihai Lupu Vlad Mihai Voiculescu Ana Caruntu Tiberiu Tebeica Constantin Caruntu Preoperative Evaluation through Dermoscopy and Reflectance Confocal Microscopy of the Lateral Excision Margins for Primary Basal Cell Carcinoma Diagnostics carcinoma basal cell microscopy confocal dermoscopy prospective studies |
| title | Preoperative Evaluation through Dermoscopy and Reflectance Confocal Microscopy of the Lateral Excision Margins for Primary Basal Cell Carcinoma |
| title_full | Preoperative Evaluation through Dermoscopy and Reflectance Confocal Microscopy of the Lateral Excision Margins for Primary Basal Cell Carcinoma |
| title_fullStr | Preoperative Evaluation through Dermoscopy and Reflectance Confocal Microscopy of the Lateral Excision Margins for Primary Basal Cell Carcinoma |
| title_full_unstemmed | Preoperative Evaluation through Dermoscopy and Reflectance Confocal Microscopy of the Lateral Excision Margins for Primary Basal Cell Carcinoma |
| title_short | Preoperative Evaluation through Dermoscopy and Reflectance Confocal Microscopy of the Lateral Excision Margins for Primary Basal Cell Carcinoma |
| title_sort | preoperative evaluation through dermoscopy and reflectance confocal microscopy of the lateral excision margins for primary basal cell carcinoma |
| topic | carcinoma basal cell microscopy confocal dermoscopy prospective studies |
| url | https://www.mdpi.com/2075-4418/11/1/120 |
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