TLR-mediated albuminuria needs TNFα-mediated cooperativity between TLRs present in hematopoietic tissues and CD80 present on non-hematopoietic tissues in mice
Transient albuminuria induced by pathogen-associated molecular patterns (PAMPs) in mice through engagement of Toll-like receptors (TLRs) is widely studied as a partial model for some forms of human nephrotic syndrome (NS). In addition to TLRs, CD80 has been shown to be essential for PAMP-mediated al...
Автори: | , , , , , , , , , , , |
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Формат: | Стаття |
Мова: | English |
Опубліковано: |
The Company of Biologists
2016-06-01
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Серія: | Disease Models & Mechanisms |
Предмети: | |
Онлайн доступ: | http://dmm.biologists.org/content/9/6/707 |