Establishing a core outcome set for blunt cerebrovascular injury: an EAST modified Delphi method consensus study
Objectives Our understanding of blunt cerebrovascular injury (BCVI) has changed significantly in recent decades, resulting in a heterogeneous description of diagnosis, treatment, and outcomes in the literature which is not suitable for data pooling. Therefore, we endeavored to develop a core outcome...
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| Format: | Article |
| Language: | English |
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BMJ Publishing Group
2023-08-01
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| Series: | Trauma Surgery & Acute Care Open |
| Online Access: | https://tsaco.bmj.com/content/8/1/e001017.full |
| _version_ | 1827139838706450432 |
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| author | Deborah M Stein Elliott R Haut Jeffry Nahmias Jason W Smith Timothy Fabian Ernest E Moore Ben L Zarzaur Kelly Vogt Walter L Biffl Saskya Byerly Rondi Gelbard Markus Ziesmann Melissa Boltz Margaret Lauerman Daniel Dante Yeh Denis D Bensard April Boyd Tor Brommeland Clay Cothren Burlew Stefan Leichtle Shelly Timmons |
| author_facet | Deborah M Stein Elliott R Haut Jeffry Nahmias Jason W Smith Timothy Fabian Ernest E Moore Ben L Zarzaur Kelly Vogt Walter L Biffl Saskya Byerly Rondi Gelbard Markus Ziesmann Melissa Boltz Margaret Lauerman Daniel Dante Yeh Denis D Bensard April Boyd Tor Brommeland Clay Cothren Burlew Stefan Leichtle Shelly Timmons |
| author_sort | Deborah M Stein |
| collection | DOAJ |
| description | Objectives Our understanding of blunt cerebrovascular injury (BCVI) has changed significantly in recent decades, resulting in a heterogeneous description of diagnosis, treatment, and outcomes in the literature which is not suitable for data pooling. Therefore, we endeavored to develop a core outcome set (COS) to help guide future BCVI research and overcome the challenge of heterogeneous outcomes reporting.Methods After a review of landmark BCVI publications, content experts were invited to participate in a modified Delphi study. For round 1, participants submitted a list of proposed core outcomes. In subsequent rounds, panelists used a 9-point Likert scale to score the proposed outcomes for importance. Core outcomes consensus was defined as >70% of scores receiving 7 to 9 and <15% of scores receiving 1 to 3. Feedback and aggregate data were shared between rounds, and four rounds of deliberation were performed to re-evaluate the variables not achieving predefined consensus criteria.Results From an initial panel of 15 experts, 12 (80%) completed all rounds. A total of 22 items were considered, with 9 items achieving consensus for inclusion as core outcomes: incidence of postadmission symptom onset, overall stroke incidence, stroke incidence stratified by type and by treatment category, stroke incidence prior to treatment initiation, time to stroke, overall mortality, bleeding complications, and injury progression on radiographic follow-up. The panel further identified four non-outcome items of high importance for reporting: time to BCVI diagnosis, use of standardized screening tool, duration of treatment, and type of therapy used.Conclusion Through a well-accepted iterative survey consensus process, content experts have defined a COS to guide future research on BCVI. This COS will be a valuable tool for researchers seeking to perform new BCVI research and will allow future projects to generate data suitable for pooled statistical analysis with enhanced statistical power.Level of evidence Level IV. |
| first_indexed | 2024-03-08T17:16:39Z |
| format | Article |
| id | doaj.art-3a8e4570e53b43c69bbd40558bd1a886 |
| institution | Directory Open Access Journal |
| issn | 2397-5776 |
| language | English |
| last_indexed | 2025-03-20T18:45:36Z |
| publishDate | 2023-08-01 |
| publisher | BMJ Publishing Group |
| record_format | Article |
| series | Trauma Surgery & Acute Care Open |
| spelling | doaj.art-3a8e4570e53b43c69bbd40558bd1a8862024-08-24T15:45:10ZengBMJ Publishing GroupTrauma Surgery & Acute Care Open2397-57762023-08-018110.1136/tsaco-2022-001017Establishing a core outcome set for blunt cerebrovascular injury: an EAST modified Delphi method consensus studyDeborah M Stein0Elliott R Haut1Jeffry Nahmias2Jason W Smith3Timothy Fabian4Ernest E Moore5Ben L Zarzaur6Kelly Vogt7Walter L Biffl8Saskya Byerly9Rondi Gelbard10Markus Ziesmann11Melissa Boltz12Margaret Lauerman13Daniel Dante Yeh14Denis D Bensard15April Boyd16Tor Brommeland17Clay Cothren Burlew18Stefan Leichtle19Shelly Timmons20University of Maryland Baltimore, Baltimore, Maryland, USADepartment of Surgery, Johns Hopkins Univ, Baltimore, Maryland, USATexas Health Presbyterian Hospital, Dallas, Texas, USASurgery, University of Louisville, Louisville, Kentucky, USASurgery, University of Tennessee Health Science Center College of Medicine, Memphis, Tennessee, USADenver Health Medical Center, Denver, Colorado, USA4 Department of Surgery, University of Wisconsin-Madison School of Medicine and Public Health, Madison, Wisconsin, USASurgery, Western University Schulich School of Medicine & Dentistry, London, Ontario, CanadaSurgery, Scripps Health, La Jolla, California, USASurgery, UTHSC COM, Memphis, Tennessee, USADepartment of Surgery, University of Alabama at Birmingham Center for Health Promotion, Birmingham, Alabama, USASurgery, University of Manitoba Max Rady College of Medicine, Winnipeg, Manitoba, CanadaDepartment of Surgery, Penn State Health Milton S Hershey Medical Center, Hershey, Pennsylvania, USASurgery, University of Maryland Baltimore, Baltimore, Maryland, USADepartment of Surgery, Ernest E Moore Shock Trauma Center, University of Colorado Denver, Denver, Colorado, USAAnschutz Medical Campus, Denver Health Medical Center, Denver, Colorado, USASurgery, University of Manitoba Max Rady College of Medicine, Winnipeg, Manitoba, CanadaNeurosurgery, Oslo University Hospital Ullevaal, Oslo, NorwaySurgery, University of Colorado Denver, Denver, Colorado, USASurgery, Virginia Commonwealth University School of Medicine, Richmond, Virginia, USANeurosurgery, Indiana University School of Medicine, Indianapolis, Indiana, USAObjectives Our understanding of blunt cerebrovascular injury (BCVI) has changed significantly in recent decades, resulting in a heterogeneous description of diagnosis, treatment, and outcomes in the literature which is not suitable for data pooling. Therefore, we endeavored to develop a core outcome set (COS) to help guide future BCVI research and overcome the challenge of heterogeneous outcomes reporting.Methods After a review of landmark BCVI publications, content experts were invited to participate in a modified Delphi study. For round 1, participants submitted a list of proposed core outcomes. In subsequent rounds, panelists used a 9-point Likert scale to score the proposed outcomes for importance. Core outcomes consensus was defined as >70% of scores receiving 7 to 9 and <15% of scores receiving 1 to 3. Feedback and aggregate data were shared between rounds, and four rounds of deliberation were performed to re-evaluate the variables not achieving predefined consensus criteria.Results From an initial panel of 15 experts, 12 (80%) completed all rounds. A total of 22 items were considered, with 9 items achieving consensus for inclusion as core outcomes: incidence of postadmission symptom onset, overall stroke incidence, stroke incidence stratified by type and by treatment category, stroke incidence prior to treatment initiation, time to stroke, overall mortality, bleeding complications, and injury progression on radiographic follow-up. The panel further identified four non-outcome items of high importance for reporting: time to BCVI diagnosis, use of standardized screening tool, duration of treatment, and type of therapy used.Conclusion Through a well-accepted iterative survey consensus process, content experts have defined a COS to guide future research on BCVI. This COS will be a valuable tool for researchers seeking to perform new BCVI research and will allow future projects to generate data suitable for pooled statistical analysis with enhanced statistical power.Level of evidence Level IV.https://tsaco.bmj.com/content/8/1/e001017.full |
| spellingShingle | Deborah M Stein Elliott R Haut Jeffry Nahmias Jason W Smith Timothy Fabian Ernest E Moore Ben L Zarzaur Kelly Vogt Walter L Biffl Saskya Byerly Rondi Gelbard Markus Ziesmann Melissa Boltz Margaret Lauerman Daniel Dante Yeh Denis D Bensard April Boyd Tor Brommeland Clay Cothren Burlew Stefan Leichtle Shelly Timmons Establishing a core outcome set for blunt cerebrovascular injury: an EAST modified Delphi method consensus study Trauma Surgery & Acute Care Open |
| title | Establishing a core outcome set for blunt cerebrovascular injury: an EAST modified Delphi method consensus study |
| title_full | Establishing a core outcome set for blunt cerebrovascular injury: an EAST modified Delphi method consensus study |
| title_fullStr | Establishing a core outcome set for blunt cerebrovascular injury: an EAST modified Delphi method consensus study |
| title_full_unstemmed | Establishing a core outcome set for blunt cerebrovascular injury: an EAST modified Delphi method consensus study |
| title_short | Establishing a core outcome set for blunt cerebrovascular injury: an EAST modified Delphi method consensus study |
| title_sort | establishing a core outcome set for blunt cerebrovascular injury an east modified delphi method consensus study |
| url | https://tsaco.bmj.com/content/8/1/e001017.full |
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