Our Cases of Secondary Narcolepsy with Three Different Etiology: Review of the Literature
Narcolepsy is neurological disorder classified among central hypersomnolences group and characterized by excessive daytime sleepiness, cataplexy, associated symptoms like hypnogogic/hypnopompic hallucinations and sleep paralysis. It is divided into two types on the basis of accompanying cataplexy. I...
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| Format: | Article |
| Language: | English |
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Galenos Yayinevi
2015-09-01
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| Series: | Türk Uyku Tıbbı Dergisi |
| Subjects: | |
| Online Access: | http://jtsm.org/archives/archive-detail/article-preview/our-cases-of-secondary-narcolepsy-with-three-diffe/11211 |
| _version_ | 1797916489636904960 |
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| author | Yusuf Savrun Aylin Bican Demir Ali Özhan Sıvacı İbrahim Bora Mehmet Zarifoğlu |
| author_facet | Yusuf Savrun Aylin Bican Demir Ali Özhan Sıvacı İbrahim Bora Mehmet Zarifoğlu |
| author_sort | Yusuf Savrun |
| collection | DOAJ |
| description | Narcolepsy is neurological disorder classified among central hypersomnolences group and characterized by excessive daytime sleepiness, cataplexy, associated symptoms like hypnogogic/hypnopompic hallucinations and sleep paralysis. It is divided into two types on the basis of accompanying cataplexy. In the pathophysiology of this disorder, which is accused an autoimmune process, hypocretin deficiency in the hypothalamus was shown. Narcolepsy is often seen as a primary disease in young population but may also occur with other disorders like cerebrovascular diseases, intracranial tumors, encephalitis, sarcoidosis, multiple sclerosis or after head trauma, infections, and vaccines; in which the disease is accepted as secondary narcolepsy. In this case report, patients presenting with excessive daytime sleepiness and diagnosed as having secondary narcolepsy due to medical causes, and who have Parkinson’s disease (PD), history of interferon use and hypothalamic involvement associated with Langerhans cell histiocytosis (LCH) were reported. Daytime sleepiness complaints should be well questioned in organic pathologies related with hypothalamus-pituitary system such as PD and similar diseases or in patients with history of drug use and secondary narcolepsy should be beared in mind. |
| first_indexed | 2024-04-10T12:57:59Z |
| format | Article |
| id | doaj.art-3a8f5cecdf8f4ebb81160ada2859eb2b |
| institution | Directory Open Access Journal |
| issn | 2148-1504 |
| language | English |
| last_indexed | 2024-04-10T12:57:59Z |
| publishDate | 2015-09-01 |
| publisher | Galenos Yayinevi |
| record_format | Article |
| series | Türk Uyku Tıbbı Dergisi |
| spelling | doaj.art-3a8f5cecdf8f4ebb81160ada2859eb2b2023-02-15T16:13:20ZengGalenos YayineviTürk Uyku Tıbbı Dergisi2148-15042015-09-0123727610.4274/jtsm.108Our Cases of Secondary Narcolepsy with Three Different Etiology: Review of the LiteratureYusuf Savrun0Aylin Bican Demir1Ali Özhan Sıvacı2İbrahim Bora3Mehmet Zarifoğlu4Uludag Üniversitesi Tip Fakültesi, Nöroloji Anabilim Dali, Bursa, TürkiyeUludag Üniversitesi Tip Fakültesi, Nöroloji Anabilim Dali, Bursa, TürkiyeUludag Üniversitesi Tip Fakültesi, Nöroloji Anabilim Dali, Bursa, TürkiyeUludag Üniversitesi Tip Fakültesi, Nöroloji Anabilim Dali, Bursa, TürkiyeUludag Üniversitesi Tip Fakültesi, Nöroloji Anabilim Dali, Bursa, TürkiyeNarcolepsy is neurological disorder classified among central hypersomnolences group and characterized by excessive daytime sleepiness, cataplexy, associated symptoms like hypnogogic/hypnopompic hallucinations and sleep paralysis. It is divided into two types on the basis of accompanying cataplexy. In the pathophysiology of this disorder, which is accused an autoimmune process, hypocretin deficiency in the hypothalamus was shown. Narcolepsy is often seen as a primary disease in young population but may also occur with other disorders like cerebrovascular diseases, intracranial tumors, encephalitis, sarcoidosis, multiple sclerosis or after head trauma, infections, and vaccines; in which the disease is accepted as secondary narcolepsy. In this case report, patients presenting with excessive daytime sleepiness and diagnosed as having secondary narcolepsy due to medical causes, and who have Parkinson’s disease (PD), history of interferon use and hypothalamic involvement associated with Langerhans cell histiocytosis (LCH) were reported. Daytime sleepiness complaints should be well questioned in organic pathologies related with hypothalamus-pituitary system such as PD and similar diseases or in patients with history of drug use and secondary narcolepsy should be beared in mind.http://jtsm.org/archives/archive-detail/article-preview/our-cases-of-secondary-narcolepsy-with-three-diffe/11211Secondary narcolepsyParkinson’s diseaseinterferonhypothalamic-hypophyseal syistemLangerhans cell histiocytosis |
| spellingShingle | Yusuf Savrun Aylin Bican Demir Ali Özhan Sıvacı İbrahim Bora Mehmet Zarifoğlu Our Cases of Secondary Narcolepsy with Three Different Etiology: Review of the Literature Türk Uyku Tıbbı Dergisi Secondary narcolepsy Parkinson’s disease interferon hypothalamic-hypophyseal syistem Langerhans cell histiocytosis |
| title | Our Cases of Secondary Narcolepsy with Three Different Etiology: Review of the Literature |
| title_full | Our Cases of Secondary Narcolepsy with Three Different Etiology: Review of the Literature |
| title_fullStr | Our Cases of Secondary Narcolepsy with Three Different Etiology: Review of the Literature |
| title_full_unstemmed | Our Cases of Secondary Narcolepsy with Three Different Etiology: Review of the Literature |
| title_short | Our Cases of Secondary Narcolepsy with Three Different Etiology: Review of the Literature |
| title_sort | our cases of secondary narcolepsy with three different etiology review of the literature |
| topic | Secondary narcolepsy Parkinson’s disease interferon hypothalamic-hypophyseal syistem Langerhans cell histiocytosis |
| url | http://jtsm.org/archives/archive-detail/article-preview/our-cases-of-secondary-narcolepsy-with-three-diffe/11211 |
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