Specific AAV2/PHP.eB-mediated gene transduction of CA2 pyramidal cells via injection into the lateral ventricle
Abstract Given its limited accessibility, the CA2 area has been less investigated compared to other subregions of the hippocampus. While the development of transgenic mice expressing Cre recombinase in the CA2 has revealed unique features of this area, the use of mouse lines has several limitations,...
Main Authors: | Kazuki Okamoto, Yuji Kamikubo, Kenta Yamauchi, Shinichiro Okamoto, Megumu Takahashi, Yoko Ishida, Masato Koike, Yuji Ikegaya, Takashi Sakurai, Hiroyuki Hioki |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2023-01-01
|
Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-022-27372-8 |
Similar Items
-
Comparison of the Transduction Capacity of AAV5 and AAV PHP.eB Serotypes in Hippocampus Astroglia
by: Anastasia Borodinova, et al.
Published: (2023-11-01) -
Structural basis of receptor usage by the engineered capsid AAV-PHP.eB
by: Seongmin Jang, et al.
Published: (2022-09-01) -
Protocol for multi-scale light microscopy/electron microscopy neuronal imaging in mouse brain tissue
by: Kenta Yamauchi, et al.
Published: (2022-09-01) -
Deletion of <i>Gtf2i</i> via Systemic Administration of AAV-PHP.eB Virus Increases Social Behavior in a Mouse Model of a Neurodevelopmental Disorder
by: Omer Ophir, et al.
Published: (2023-08-01) -
Fluorochromized tyramide-glucose oxidase as a multiplex fluorescent tyramide signal amplification system for histochemical analysis
by: Kenta Yamauchi, et al.
Published: (2022-09-01)