lncRNA ZFAS1 promotes intervertebral disc degeneration by upregulating AAK1

lncRNA ZFAS1 promotes intervertebral disc degeneration by upregulating AAK1

We investigated the function of lncRNA zinc finger antisense 1 (ZFAS1) in intervertebral disc degeneration (IDD) progression in vitro and in vivo. Nucleus pulposus (NP) tissues were obtained from 20 patients with IDD. IL-1β was used to stimulate primary NP cells to establish the IDD models in vitro....

Full description

Bibliographic Details
Main Authors: Wang Zheng, Liu Bin, Ma Xiangyu, Wang Yu, Han Wenfeng, Xiang Liangbi
Format: Article
Language:English
Published: De Gruyter 2022-12-01
Series:Open Medicine
Subjects:
intervertebral disc degeneration
zfas1
apoptosis, ecm degradation
aak1
Online Access:https://doi.org/10.1515/med-2022-0530

Similar Items

Similar Items