Frequency modulation of a bacterial quorum sensing response
Quorum-sensing bacteria produce and secrete autoinducers that trigger a behavioral change in the population when reaching a certain threshold. Here, Bettenworth et al. show that autoinducer synthase gene expression in Sinorhizobium meliloti occurs in asynchronous stochastic pulses, and that physiolo...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2022-05-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-022-30307-6 |
| _version_ | 1811338861253492736 |
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| author | Vera Bettenworth Simon van Vliet Bartosz Turkowyd Annika Bamberger Heiko Wendt Matthew McIntosh Wieland Steinchen Ulrike Endesfelder Anke Becker |
| author_facet | Vera Bettenworth Simon van Vliet Bartosz Turkowyd Annika Bamberger Heiko Wendt Matthew McIntosh Wieland Steinchen Ulrike Endesfelder Anke Becker |
| author_sort | Vera Bettenworth |
| collection | DOAJ |
| description | Quorum-sensing bacteria produce and secrete autoinducers that trigger a behavioral change in the population when reaching a certain threshold. Here, Bettenworth et al. show that autoinducer synthase gene expression in Sinorhizobium meliloti occurs in asynchronous stochastic pulses, and that physiological cues modulate pulse frequency and, consequently, response behavior dynamics. Frequency-modulated pulsing in autoinducer synthase gene expression thus represents a time-based mechanism for information integration and collective decision-making. |
| first_indexed | 2024-04-13T18:16:53Z |
| format | Article |
| id | doaj.art-3a908f0888db4e71b78959ca0f5b5f14 |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-04-13T18:16:53Z |
| publishDate | 2022-05-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-3a908f0888db4e71b78959ca0f5b5f142022-12-22T02:35:38ZengNature PortfolioNature Communications2041-17232022-05-0113111210.1038/s41467-022-30307-6Frequency modulation of a bacterial quorum sensing responseVera Bettenworth0Simon van Vliet1Bartosz Turkowyd2Annika Bamberger3Heiko Wendt4Matthew McIntosh5Wieland Steinchen6Ulrike Endesfelder7Anke Becker8Center for Synthetic Microbiology (SYNMIKRO), Philipps-Universität MarburgBiozentrum, University of BaselCenter for Synthetic Microbiology (SYNMIKRO), Philipps-Universität MarburgCenter for Synthetic Microbiology (SYNMIKRO), Philipps-Universität MarburgCenter for Synthetic Microbiology (SYNMIKRO), Philipps-Universität MarburgCenter for Synthetic Microbiology (SYNMIKRO), Philipps-Universität MarburgCenter for Synthetic Microbiology (SYNMIKRO), Philipps-Universität MarburgCenter for Synthetic Microbiology (SYNMIKRO), Philipps-Universität MarburgCenter for Synthetic Microbiology (SYNMIKRO), Philipps-Universität MarburgQuorum-sensing bacteria produce and secrete autoinducers that trigger a behavioral change in the population when reaching a certain threshold. Here, Bettenworth et al. show that autoinducer synthase gene expression in Sinorhizobium meliloti occurs in asynchronous stochastic pulses, and that physiological cues modulate pulse frequency and, consequently, response behavior dynamics. Frequency-modulated pulsing in autoinducer synthase gene expression thus represents a time-based mechanism for information integration and collective decision-making.https://doi.org/10.1038/s41467-022-30307-6 |
| spellingShingle | Vera Bettenworth Simon van Vliet Bartosz Turkowyd Annika Bamberger Heiko Wendt Matthew McIntosh Wieland Steinchen Ulrike Endesfelder Anke Becker Frequency modulation of a bacterial quorum sensing response Nature Communications |
| title | Frequency modulation of a bacterial quorum sensing response |
| title_full | Frequency modulation of a bacterial quorum sensing response |
| title_fullStr | Frequency modulation of a bacterial quorum sensing response |
| title_full_unstemmed | Frequency modulation of a bacterial quorum sensing response |
| title_short | Frequency modulation of a bacterial quorum sensing response |
| title_sort | frequency modulation of a bacterial quorum sensing response |
| url | https://doi.org/10.1038/s41467-022-30307-6 |
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