he Effects of Ovulation Documentation before Insemination on Intrauterine Insemination Cycle Outcomes: A Retrospective Analysis

Introduction: Ovulation is the key event in Intrauterine Insemination (IUI) cycles. Monitoring ovulation prior to insemination will help to alter insemination time to improve pregnancy rate. Aim: To compare pregnancy rates and live birth rates in presence and absence of ultrasonographic feature...

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Main Authors: Sujata Pradhan, Padmalaya Thakur
Format: Article
Language:English
Published: JCDR Research and Publications Private Limited 2021-03-01
Series:Journal of Clinical and Diagnostic Research
Subjects:
Online Access:https://www.jcdr.net/articles/PDF/14629/46802_CE[Ra1]_F(SHU)_PF1(AKA_SHU)_PFA(AKA_KM_SHU)_PN(SHU).pdf
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author Sujata Pradhan
Padmalaya Thakur
author_facet Sujata Pradhan
Padmalaya Thakur
author_sort Sujata Pradhan
collection DOAJ
description Introduction: Ovulation is the key event in Intrauterine Insemination (IUI) cycles. Monitoring ovulation prior to insemination will help to alter insemination time to improve pregnancy rate. Aim: To compare pregnancy rates and live birth rates in presence and absence of ultrasonographic features of ovulation before insemination in IUI cycles. Materials and Methods: This was a retrospective cohort study conducted in a Institute of Medical Sciences and SUM Hospital, Bhubaneswar. Three hundred eighty eight IUI cycles performed in the period of January 2017 to December 2018 were analysed. On the day of IUI prior to insemination, transvaginal ultrasonography was done 36-38 hours after ovulation trigger to document ovulation. Presumptive signs of ovulation were documented in 201 cycles (Group A) and there was no feature suggestive of ovulation in 187 cycles (Group B). In all the cycles, single insemination was performed at 38-40 hours after ovulation trigger. Baseline characteristics were compared. Mann-Whitney U test was used to compare continuous variables. Chi-square test and Fisher’s-exact test were applied to find out the differences in the categorical variables as well as the pregnancy outcomes among the groups. Pregnancy rate and live birth rate were considered as the primary outcomes. Results: Pregnancy rate (17.9% vs 18.2%, p-value=0.945) and live birth rate (17.9% vs 16.0%, p-value=0.625) were similar irrespective of ovulation status documented in ultrasonography performed before insemination. Conclusion: IUI cycle outcomes are independent of the ovulation status documented before insemination.
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spelling doaj.art-3a90bd422e7f4d0e8c2d22c1364741cf2022-12-21T21:24:47ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2021-03-01153QC06QC0810.7860/JCDR/2021/46802.14629he Effects of Ovulation Documentation before Insemination on Intrauterine Insemination Cycle Outcomes: A Retrospective AnalysisSujata Pradhan0 Padmalaya Thakur1Associate Professor, Department of Obstetrics and Gynaecology, Institute of Medical Sciences and SUM Hospital, SOA Deemed to be University, Bhubaneswar, Odisha, India.Assistant Professor, Department of Obstetrics and Gynaecology, Institute of Medical Sciences and SUM Hospital, SOA Deemed to be University, Bhubaneswar, Odisha, India.Introduction: Ovulation is the key event in Intrauterine Insemination (IUI) cycles. Monitoring ovulation prior to insemination will help to alter insemination time to improve pregnancy rate. Aim: To compare pregnancy rates and live birth rates in presence and absence of ultrasonographic features of ovulation before insemination in IUI cycles. Materials and Methods: This was a retrospective cohort study conducted in a Institute of Medical Sciences and SUM Hospital, Bhubaneswar. Three hundred eighty eight IUI cycles performed in the period of January 2017 to December 2018 were analysed. On the day of IUI prior to insemination, transvaginal ultrasonography was done 36-38 hours after ovulation trigger to document ovulation. Presumptive signs of ovulation were documented in 201 cycles (Group A) and there was no feature suggestive of ovulation in 187 cycles (Group B). In all the cycles, single insemination was performed at 38-40 hours after ovulation trigger. Baseline characteristics were compared. Mann-Whitney U test was used to compare continuous variables. Chi-square test and Fisher’s-exact test were applied to find out the differences in the categorical variables as well as the pregnancy outcomes among the groups. Pregnancy rate and live birth rate were considered as the primary outcomes. Results: Pregnancy rate (17.9% vs 18.2%, p-value=0.945) and live birth rate (17.9% vs 16.0%, p-value=0.625) were similar irrespective of ovulation status documented in ultrasonography performed before insemination. Conclusion: IUI cycle outcomes are independent of the ovulation status documented before insemination.https://www.jcdr.net/articles/PDF/14629/46802_CE[Ra1]_F(SHU)_PF1(AKA_SHU)_PFA(AKA_KM_SHU)_PN(SHU).pdfbirthpregnancyultrasonography
spellingShingle Sujata Pradhan
Padmalaya Thakur
he Effects of Ovulation Documentation before Insemination on Intrauterine Insemination Cycle Outcomes: A Retrospective Analysis
Journal of Clinical and Diagnostic Research
birth
pregnancy
ultrasonography
title he Effects of Ovulation Documentation before Insemination on Intrauterine Insemination Cycle Outcomes: A Retrospective Analysis
title_full he Effects of Ovulation Documentation before Insemination on Intrauterine Insemination Cycle Outcomes: A Retrospective Analysis
title_fullStr he Effects of Ovulation Documentation before Insemination on Intrauterine Insemination Cycle Outcomes: A Retrospective Analysis
title_full_unstemmed he Effects of Ovulation Documentation before Insemination on Intrauterine Insemination Cycle Outcomes: A Retrospective Analysis
title_short he Effects of Ovulation Documentation before Insemination on Intrauterine Insemination Cycle Outcomes: A Retrospective Analysis
title_sort he effects of ovulation documentation before insemination on intrauterine insemination cycle outcomes a retrospective analysis
topic birth
pregnancy
ultrasonography
url https://www.jcdr.net/articles/PDF/14629/46802_CE[Ra1]_F(SHU)_PF1(AKA_SHU)_PFA(AKA_KM_SHU)_PN(SHU).pdf
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